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Lancet子刊:新疆民众肺结核发病率仍然不容乐观

2016-06-07 MedSci MedSci原创

背景中国西部地区的结核病控制工作进展最慢,结核患病率在国内最高。该研究的目的在于评估引入结核病控制规划后新疆地区肺结核的患病率。方法 在这个以人群为基础的横断面研究中,研究人员采用多级、分层、随机的方式抽取样本,统计痰检阳性和(或)细菌学测试阳性的肺结核成人(≥15岁、在新疆居住时长超过6个月)的人数。筛查策略和诊断指南符合WHO标准。研究人员结合逆概率加权和缺失数据的多重替代法估计肺结核患者的发

背景

中国西部地区的结核病控制工作进展最慢,结核患病率在国内最高。该研究的目的在于评估引入结核病控制规划后新疆地区肺结核的患病率。

方法

在这个以人群为基础的横断面研究中,研究人员采用多级、分层、随机的方式抽取样本,统计痰检阳性和(或)细菌学测试阳性的肺结核成人(≥15岁、在新疆居住时长超过6个月)的人数。筛查策略和诊断指南符合WHO标准。研究人员结合逆概率加权和缺失数据的多重替代法估计肺结核患者的发生率,并与2010年全国肺结核患者调查数据和2000年新疆肺结核患者发生率调查进行对比。

结果

2010年9月1日-2011年7月31日期间,共有31081名符合标准,其中29835人(96.0%)参与研究。其中50人(0.2%)痰检阳性,101人(0.3%)细菌学检查阳性。痰检阳性的加权发生率为170人/100000人(95%CI:103-233),细菌学检查阳性加权发生率为430人/10万人(249-611)。相比2000年新疆肺结核患者发生率调查结果,痰检阳性发生率下降26.4%(2000年:231/10万人[95%CI:148-314]),细菌学检查阳性发生率增加了17.8%(2000年:365人/10万人[237-493])。2010-2011年新疆肺结核发生率调查结果显示,无论哪种年龄段和性别,肺结核发生率都高于2010年全国肺结核调查。

结论

尽管中国其他地区肺结核发病率显著降低,但是新疆地区肺结核患者的发病率仍然很高,政府仍然需要加大结核病筛查的强度和力度,采取有效治疗方案。

原始出处:
Prevalence of pulmonary tuberculosis in western China in 2010–11: a population-based, cross-sectional survey,Peierdun Mijiti,et al,The Lancet Global Health 6,June,2016


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    2017-05-11 howi
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    2017-01-02 yaanren
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    2016-09-18 1e10c84am36(暂无匿称)

    不错哦继续关注

    0

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    2016-08-20 doctorJiangchao

    继续学习

    0

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    2016-08-20 doctorJiangchao

    继续关注

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