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Diabetes Obes Metab:强化血压控制对2型糖尿病患者的影响!

2018-02-10 xing.T MedSci原创

由此可见,在这项事后分析中,对2型糖尿病患者进行持续强化血压控制的益处在随访的9年期间持续存在。

虽然指南推荐对2型糖尿病(T2DM)和心血管风险升高患者进行严格的血压控制,但这种方法的长期效果尚不清楚。近日,代谢内分泌疾病领域权威杂志Diabetes Obesity & Metabolism上发表了一篇研究文章。研究人员旨在明确强化血压控制随访9年以上对2型糖尿病患者临床结局的影响。

研究人员纳入了ACCORD BP研究中接受标准血糖控制的伴有心血管疾病、慢性肾脏疾病、年龄≥75年或10年冠心病风险≥15%的参与者队列。参与者被随机分为强化降压(收缩压<120mmHg)或标准(收缩压<140mmHg)血压控制组,平均治疗5年。随后的观察随访平均为4年。

在平均9年的随访期间,强化血压控制可以降低心血管死亡、非致死性心肌梗死和非致命性卒中的复合事件约25%(风险比为0.75;95%可信区间为0.60-0.95;P=0.02)。非致命性心肌梗死减少可驱动总体获益(P=0.01)。

由此可见,在这项事后分析中,对2型糖尿病患者进行持续强化血压控制的益处在随访的9年期间持续存在。

原始出处:

Leo F. Buckley,et al. Effect of Intensive Blood Pressure Control in Patients with Type 2 Diabetes Mellitus Over 9 Years of Follow-Up: A Subgroup Analysis of High-Risk ACCORDION Trial Participants. Diabetes Obesity & Metabolism.2018. http://onlinelibrary.wiley.com/doi/10.1111/dom.13248/full

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    2018-12-10 一闲
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  5. 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encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Mon Feb 12 01:34:00 CST 2018, time=2018-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=286827, encodeId=4a4328682e99, content=血压控制到正常范围对心血管有好处, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzcjoLTEEgkSSQ8pVIiaf4a4INaoMLBV16QEk3dvvBRpicwIwmDGv0jePErJ4aE9ibVBDPtkialQLT9Bs/0, createdBy=04811949400, createdName=邓启付, createdTime=Sat Feb 10 16:43:17 CST 2018, time=2018-02-10, status=1, ipAttribution=)]
  6. 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createdName=aids213, createdTime=Mon Feb 12 01:34:00 CST 2018, time=2018-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1446300, encodeId=79f2144630042, content=<a href='/topic/show?id=875e88946d1' target=_blank style='color:#2F92EE;'>#血压控制#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88946, encryptionId=875e88946d1, topicName=血压控制)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28a45200046, createdName=gj0733, createdTime=Mon Feb 12 01:34:00 CST 2018, time=2018-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474431, encodeId=2fb514e443198, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Mon Feb 12 01:34:00 CST 2018, time=2018-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=286827, encodeId=4a4328682e99, content=血压控制到正常范围对心血管有好处, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzcjoLTEEgkSSQ8pVIiaf4a4INaoMLBV16QEk3dvvBRpicwIwmDGv0jePErJ4aE9ibVBDPtkialQLT9Bs/0, createdBy=04811949400, createdName=邓启付, createdTime=Sat Feb 10 16:43:17 CST 2018, time=2018-02-10, status=1, ipAttribution=)]
    2018-07-07 guojianrong
  7. 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    2018-02-10 邓启付

    血压控制到正常范围对心血管有好处

    0

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