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Am J Clin Nutr:多吃水果可降低男性这些心血管风险

2016-08-06 Mechront 译 MedSci原创

目的:虽然增加水果摄入量可减少心血管疾病(CVD)风险,但是水果中最有益的关键成分是什么?习惯性摄入黄酮类化合物,特别是花青素和黄酮类(> 90%习惯性摄入来自水果),与妇女心血管疾病的风险降低有关,但这种联系对于男性而言是未知的。我们探究了卫生专业人员习惯性的花青素和黄酮的摄入量与冠心病和脑卒中关系。方法:我们随访了43880名没有被诊断为心血管疾病或癌症的健康人。使用验证的食物频率问卷调

目的:虽然增加水果摄入量可减少心血管疾病(CVD)风险,但是水果中最有益的关键成分是什么?习惯性摄入黄酮类化合物,特别是花青素和黄酮类(> 90%习惯性摄入来自水果),与妇女心血管疾病的风险降低有关,但这种联系对于男性而言是未知的。我们探究了卫生专业人员习惯性的花青素和黄酮的摄入量与冠心病和脑卒中关系。

方法:我们随访了43880名没有被诊断为心血管疾病或癌症的健康人。使用验证的食物频率问卷调查评估参与者黄酮类摄入量。

结果:在24年随访期间,发生了4046例心肌梗死和1572例脑卒中。虽然较高的花青素摄入量与总或致命性心肌梗死的风险无关,但是校正多因素后,观察到花青素摄入量与非致死性心肌梗死呈负相关(HR: 0.87; 95% CI: 0.75, 1.00; P = 0.04; P-趋势= 0.098);在正常血压者中这种相关性更强(HR: 0.81; 95% CI: 0.69, 0.96; P-交互作用 = 0.03)。

花青素摄入量与卒中风险无关。虽然黄酮的摄入量与心肌梗死或总卒中风险无关,但是更高的摄入量与更低的缺血性卒中风险有关(HR: 0.78; 95% CI: 0.62, 0.97; P = 0.03, P-趋势 = 0.059);尤其是≥65岁的人群中,这种联系最强(P-交互作用 = 0.04)。

结论:基于水果的更高的黄酮摄入量与男性较低的非致死性心肌梗死、缺血性卒中风险有关。背后具体的机制还需要进一步的研究。

原始出处:

Cassidy A.et al.Habitual intake of anthocyanins and flavanones and risk of cardiovascular disease in men.Am J Clin Nutr. 2016 Aug 3. pii: ajcn133132. [Epub ahead of print]

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  1. 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    2016-09-20 1e10c84am36(暂无匿称)

    文章很好,非常有益

    0

  3. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c09d1605573, createdName=aa6081, createdTime=Sun Aug 07 09:39:00 CST 2016, time=2016-08-07, status=1, ipAttribution=)]
    2016-09-12 舒心和人

    分析的很有道理,要是机制搞明白了就更好了

    0

  4. 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level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzTetibytbqFDmFITWHyBWbxU7S9MYibgPSqvu0sYteH0N6zXqbU0Kf3Mbdb7yWM1Kud3zPgYBibE2SZ/0, createdBy=da7696924, createdName=qingfengqishi5, createdTime=Tue Aug 09 16:58:00 CST 2016, time=2016-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96772, encodeId=668b96e72d9, content=科学饮食促进健康!, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sun Aug 07 17:57:00 CST 2016, time=2016-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96679, encodeId=340c966e995, content=以后多吃水果了, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c09d1605573, createdName=aa6081, createdTime=Sun Aug 07 09:39:00 CST 2016, time=2016-08-07, status=1, ipAttribution=)]
    2016-09-11 1e10c84am36(暂无匿称)

    己拜读,受益匪浅

    0

  5. 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level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzTetibytbqFDmFITWHyBWbxU7S9MYibgPSqvu0sYteH0N6zXqbU0Kf3Mbdb7yWM1Kud3zPgYBibE2SZ/0, createdBy=da7696924, createdName=qingfengqishi5, createdTime=Tue Aug 09 16:58:00 CST 2016, time=2016-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96772, encodeId=668b96e72d9, content=科学饮食促进健康!, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sun Aug 07 17:57:00 CST 2016, time=2016-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96679, encodeId=340c966e995, content=以后多吃水果了, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c09d1605573, createdName=aa6081, createdTime=Sun Aug 07 09:39:00 CST 2016, time=2016-08-07, status=1, ipAttribution=)]
    2016-09-06 李东泽

    很好,不错,以后会多学习

    0

  6. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c09d1605573, createdName=aa6081, createdTime=Sun Aug 07 09:39:00 CST 2016, time=2016-08-07, status=1, ipAttribution=)]
    2016-08-27 ylzr123

    赞!文章有深度,值得收藏拜读。

    0

  7. 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level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzTetibytbqFDmFITWHyBWbxU7S9MYibgPSqvu0sYteH0N6zXqbU0Kf3Mbdb7yWM1Kud3zPgYBibE2SZ/0, createdBy=da7696924, createdName=qingfengqishi5, createdTime=Tue Aug 09 16:58:00 CST 2016, time=2016-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96772, encodeId=668b96e72d9, content=科学饮食促进健康!, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sun Aug 07 17:57:00 CST 2016, time=2016-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96679, encodeId=340c966e995, content=以后多吃水果了, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c09d1605573, createdName=aa6081, createdTime=Sun Aug 07 09:39:00 CST 2016, time=2016-08-07, status=1, ipAttribution=)]
    2016-08-14 忠诚向上

    好好学习

    0

  8. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sat Aug 27 12:52:00 CST 2016, time=2016-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=98603, encodeId=baf298603cc, content=好好学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Aug 14 18:03:00 CST 2016, time=2016-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=97036, encodeId=12069e036e5, content=健康饮食有利于身体健康!, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzTetibytbqFDmFITWHyBWbxU7S9MYibgPSqvu0sYteH0N6zXqbU0Kf3Mbdb7yWM1Kud3zPgYBibE2SZ/0, createdBy=da7696924, createdName=qingfengqishi5, createdTime=Tue Aug 09 16:58:00 CST 2016, time=2016-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96772, encodeId=668b96e72d9, content=科学饮食促进健康!, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sun Aug 07 17:57:00 CST 2016, time=2016-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96679, encodeId=340c966e995, content=以后多吃水果了, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c09d1605573, createdName=aa6081, createdTime=Sun Aug 07 09:39:00 CST 2016, time=2016-08-07, status=1, ipAttribution=)]
    2016-08-09 qingfengqishi5

    健康饮食有利于身体健康!

    0

  9. 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level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzTetibytbqFDmFITWHyBWbxU7S9MYibgPSqvu0sYteH0N6zXqbU0Kf3Mbdb7yWM1Kud3zPgYBibE2SZ/0, createdBy=da7696924, createdName=qingfengqishi5, createdTime=Tue Aug 09 16:58:00 CST 2016, time=2016-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96772, encodeId=668b96e72d9, content=科学饮食促进健康!, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sun Aug 07 17:57:00 CST 2016, time=2016-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96679, encodeId=340c966e995, content=以后多吃水果了, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c09d1605573, createdName=aa6081, createdTime=Sun Aug 07 09:39:00 CST 2016, time=2016-08-07, status=1, ipAttribution=)]
    2016-08-07 jyzxjiangqin

    科学饮食促进健康!

    0

  10. 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level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzTetibytbqFDmFITWHyBWbxU7S9MYibgPSqvu0sYteH0N6zXqbU0Kf3Mbdb7yWM1Kud3zPgYBibE2SZ/0, createdBy=da7696924, createdName=qingfengqishi5, createdTime=Tue Aug 09 16:58:00 CST 2016, time=2016-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96772, encodeId=668b96e72d9, content=科学饮食促进健康!, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sun Aug 07 17:57:00 CST 2016, time=2016-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96679, encodeId=340c966e995, content=以后多吃水果了, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c09d1605573, createdName=aa6081, createdTime=Sun Aug 07 09:39:00 CST 2016, time=2016-08-07, status=1, ipAttribution=)]
    2016-08-07 aa6081

    以后多吃水果了

    0

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英国格拉斯哥大学的一项最新研究发现,柑橘类水果尤其是柚子,含有可预防血管炎症的生物分子,未来有望据此开发出成本更低、副作用更小的心血管疾病防治药物。相关研究论文刊登在了近期出版的《生物化学杂志》上。【原文下载】 研究人员表示,许多心血管疾病都与血液中免疫细胞的过度反应有关,这些免疫细胞会黏附在血管内皮细胞上,引发炎症并阻塞血管,导致高血压、心脏病等疾病。研究人员发现,黄酮类小分子(f

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