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J Gastroen Hepatol：5-氨基水杨酸类药物对结肠憩室炎复发预防无效

2017-12-29 zhangfan MedSci原创

5-氨基水杨酸类药物结肠憩室炎复发
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根据现有的研究表明，5-氨基水杨酸类药物不能预防结肠憩室炎复发

世界范围内结肠憩室病的患病率随着人口年龄的增长不断增加，预计全球25%的人群经历过憩室炎。确切的复发性憩室炎预防方法尚不清楚。5-氨基水杨酸类(5-ASA)主要用于抗炎，同时也是复发性憩室炎的主要预防手段。近日研究人员对5-ASA预防憩室炎复发的效果和安全性进行了评估。

本次研究是系统综述以及荟萃分析研究，对 MEDLINE， EMBASE， Web of Science以及the Cochrane library数据库的相关研究资料进行考察。数据合并采用随机效应模型，计算比值比(RR)以及95%置信区间(CI)。科克伦Q和I平方统计用于异质性评估。

研究考察了329篇相关研究文章，其中7篇纳入本次荟萃分析。研究发现，5-ASA 相对于安慰剂，对憩室炎复发的预防效果不显著(RR 0.86， 95% CI 0.63-1.17， I2 = 60%)；不良事件率与安慰剂相比未见显著差异(RR 0.97， 95% CI 0.84-1.11， I2 = 45%)，但本次研究样本数量较少，结果具有很大的偏倚风险。

根据现有的研究表明，5-氨基水杨酸类药物不能预防结肠憩室炎复发。

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    2018-03-18 许安

    #GAS#

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    2018-01-04 ms24272190615788285182

    #AST#

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    2018-01-24 limedical1974

    #水杨酸#

    0

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time=2017-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1585282, encodeId=6816158528252, content=<a href='/topic/show?id=aadf139959' target=_blank style='color:#2F92EE;'>#5-氨基水杨酸类药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1399, encryptionId=aadf139959, topicName=5-氨基水杨酸类药物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f21317152169, createdName=neurowu, createdTime=Sat Dec 30 23:50:00 CST 2017, time=2017-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=273498, encodeId=e60d2e3498e9, content=学习了.涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Fri Dec 29 12:00:14 CST 2017, time=2017-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=273475, encodeId=9ca92e347589, content=了解了解.学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Fri Dec 29 10:17:55 CST 2017, time=2017-12-29, status=1, ipAttribution=)]
    2017-12-30 1249883fm12暂无昵称

    #憩室炎#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2072022, encodeId=d1e220e202287, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Sun Mar 18 18:50:00 CST 2018, time=2018-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1711319, encodeId=3f901e11319cc, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, 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href='/topic/show?id=14d853e8918' target=_blank style='color:#2F92EE;'>#憩室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53789, encryptionId=14d853e8918, topicName=憩室)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=33b211483971, createdName=zutt, createdTime=Sat Dec 30 23:50:00 CST 2017, time=2017-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1523805, encodeId=31db152380557, content=<a href='/topic/show?id=7170e87563e' target=_blank style='color:#2F92EE;'>#结肠憩室炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78756, encryptionId=7170e87563e, topicName=结肠憩室炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4e5311558208, createdName=guojianrong, createdTime=Sat Dec 30 23:50:00 CST 2017, time=2017-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1585282, encodeId=6816158528252, content=<a href='/topic/show?id=aadf139959' target=_blank style='color:#2F92EE;'>#5-氨基水杨酸类药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1399, encryptionId=aadf139959, topicName=5-氨基水杨酸类药物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f21317152169, createdName=neurowu, createdTime=Sat Dec 30 23:50:00 CST 2017, time=2017-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=273498, encodeId=e60d2e3498e9, content=学习了.涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Fri Dec 29 12:00:14 CST 2017, time=2017-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=273475, encodeId=9ca92e347589, content=了解了解.学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Fri Dec 29 10:17:55 CST 2017, time=2017-12-29, status=1, ipAttribution=)]
    2017-12-30 gwc384

    #EPA#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2072022, encodeId=d1e220e202287, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Sun Mar 18 18:50:00 CST 2018, time=2018-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1711319, encodeId=3f901e11319cc, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, 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href='/topic/show?id=14d853e8918' target=_blank style='color:#2F92EE;'>#憩室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53789, encryptionId=14d853e8918, topicName=憩室)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=33b211483971, createdName=zutt, createdTime=Sat Dec 30 23:50:00 CST 2017, time=2017-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1523805, encodeId=31db152380557, content=<a href='/topic/show?id=7170e87563e' target=_blank style='color:#2F92EE;'>#结肠憩室炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78756, encryptionId=7170e87563e, topicName=结肠憩室炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4e5311558208, createdName=guojianrong, createdTime=Sat Dec 30 23:50:00 CST 2017, time=2017-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1585282, encodeId=6816158528252, content=<a href='/topic/show?id=aadf139959' target=_blank style='color:#2F92EE;'>#5-氨基水杨酸类药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1399, encryptionId=aadf139959, topicName=5-氨基水杨酸类药物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f21317152169, createdName=neurowu, createdTime=Sat Dec 30 23:50:00 CST 2017, time=2017-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=273498, encodeId=e60d2e3498e9, content=学习了.涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Fri Dec 29 12:00:14 CST 2017, time=2017-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=273475, encodeId=9ca92e347589, content=了解了解.学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Fri Dec 29 10:17:55 CST 2017, time=2017-12-29, status=1, ipAttribution=)]
    2017-12-30 zutt

    #憩室#

    0

  7. 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level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53791, encryptionId=b5be53e91fc, topicName=憩室炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d4902500082, createdName=1249883fm12暂无昵称, createdTime=Sat Dec 30 23:50:00 CST 2017, time=2017-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1426962, encodeId=ee47142696297, content=<a href='/topic/show?id=221d685172' target=_blank style='color:#2F92EE;'>#EPA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6851, encryptionId=221d685172, topicName=EPA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4a9b4077760, createdName=gwc384, createdTime=Sat Dec 30 23:50:00 CST 2017, time=2017-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1522721, encodeId=077a1522e2158, content=<a href='/topic/show?id=14d853e8918' target=_blank style='color:#2F92EE;'>#憩室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53789, encryptionId=14d853e8918, topicName=憩室)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=33b211483971, createdName=zutt, createdTime=Sat Dec 30 23:50:00 CST 2017, time=2017-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1523805, encodeId=31db152380557, content=<a href='/topic/show?id=7170e87563e' target=_blank style='color:#2F92EE;'>#结肠憩室炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78756, encryptionId=7170e87563e, topicName=结肠憩室炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4e5311558208, createdName=guojianrong, createdTime=Sat Dec 30 23:50:00 CST 2017, time=2017-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1585282, encodeId=6816158528252, content=<a href='/topic/show?id=aadf139959' target=_blank style='color:#2F92EE;'>#5-氨基水杨酸类药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1399, encryptionId=aadf139959, topicName=5-氨基水杨酸类药物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f21317152169, createdName=neurowu, createdTime=Sat Dec 30 23:50:00 CST 2017, time=2017-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=273498, encodeId=e60d2e3498e9, content=学习了.涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Fri Dec 29 12:00:14 CST 2017, time=2017-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=273475, encodeId=9ca92e347589, content=了解了解.学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Fri Dec 29 10:17:55 CST 2017, time=2017-12-29, status=1, ipAttribution=)]
    2017-12-30 guojianrong

    #结肠憩室炎#

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=2072022, encodeId=d1e220e202287, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Sun Mar 18 18:50:00 CST 2018, time=2018-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1711319, encodeId=3f901e11319cc, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Thu Jan 04 20:50:00 CST 2018, time=2018-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1984048, encodeId=fab419840489e, content=<a href='/topic/show?id=e3f464183db' target=_blank style='color:#2F92EE;'>#水杨酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64183, encryptionId=e3f464183db, topicName=水杨酸)], attachment=null, authenticateStatus=null, createdAvatar=http://login.medsci.cn/upload/avatar/cc81592b507031e3cfd8d4c57911d98b/62c22832a9474aea1ca90ca058aebc03.jpg, createdBy=bed5446, createdName=limedical1974, createdTime=Wed Jan 24 00:50:00 CST 2018, time=2018-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1391441, encodeId=4d041391441e4, content=<a href='/topic/show?id=b5be53e91fc' target=_blank style='color:#2F92EE;'>#憩室炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53791, encryptionId=b5be53e91fc, topicName=憩室炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d4902500082, createdName=1249883fm12暂无昵称, createdTime=Sat Dec 30 23:50:00 CST 2017, time=2017-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1426962, encodeId=ee47142696297, content=<a href='/topic/show?id=221d685172' target=_blank style='color:#2F92EE;'>#EPA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6851, encryptionId=221d685172, topicName=EPA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4a9b4077760, createdName=gwc384, createdTime=Sat Dec 30 23:50:00 CST 2017, time=2017-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1522721, encodeId=077a1522e2158, content=<a href='/topic/show?id=14d853e8918' target=_blank style='color:#2F92EE;'>#憩室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53789, encryptionId=14d853e8918, topicName=憩室)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=33b211483971, createdName=zutt, createdTime=Sat Dec 30 23:50:00 CST 2017, time=2017-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1523805, encodeId=31db152380557, content=<a href='/topic/show?id=7170e87563e' target=_blank style='color:#2F92EE;'>#结肠憩室炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78756, encryptionId=7170e87563e, topicName=结肠憩室炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4e5311558208, createdName=guojianrong, createdTime=Sat Dec 30 23:50:00 CST 2017, time=2017-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1585282, encodeId=6816158528252, content=<a href='/topic/show?id=aadf139959' target=_blank style='color:#2F92EE;'>#5-氨基水杨酸类药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1399, encryptionId=aadf139959, topicName=5-氨基水杨酸类药物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f21317152169, createdName=neurowu, createdTime=Sat Dec 30 23:50:00 CST 2017, time=2017-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=273498, encodeId=e60d2e3498e9, content=学习了.涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Fri Dec 29 12:00:14 CST 2017, time=2017-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=273475, encodeId=9ca92e347589, content=了解了解.学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Fri Dec 29 10:17:55 CST 2017, time=2017-12-29, status=1, ipAttribution=)]
    2017-12-30 neurowu

    #5-氨基水杨酸类药物#

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=2072022, encodeId=d1e220e202287, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Sun Mar 18 18:50:00 CST 2018, time=2018-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1711319, encodeId=3f901e11319cc, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Thu Jan 04 20:50:00 CST 2018, time=2018-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1984048, encodeId=fab419840489e, content=<a href='/topic/show?id=e3f464183db' target=_blank style='color:#2F92EE;'>#水杨酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64183, encryptionId=e3f464183db, topicName=水杨酸)], attachment=null, authenticateStatus=null, createdAvatar=http://login.medsci.cn/upload/avatar/cc81592b507031e3cfd8d4c57911d98b/62c22832a9474aea1ca90ca058aebc03.jpg, createdBy=bed5446, createdName=limedical1974, createdTime=Wed Jan 24 00:50:00 CST 2018, time=2018-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1391441, encodeId=4d041391441e4, content=<a href='/topic/show?id=b5be53e91fc' target=_blank style='color:#2F92EE;'>#憩室炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53791, encryptionId=b5be53e91fc, topicName=憩室炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d4902500082, createdName=1249883fm12暂无昵称, createdTime=Sat Dec 30 23:50:00 CST 2017, time=2017-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1426962, encodeId=ee47142696297, content=<a href='/topic/show?id=221d685172' target=_blank style='color:#2F92EE;'>#EPA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6851, encryptionId=221d685172, topicName=EPA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4a9b4077760, createdName=gwc384, createdTime=Sat Dec 30 23:50:00 CST 2017, time=2017-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1522721, encodeId=077a1522e2158, content=<a href='/topic/show?id=14d853e8918' target=_blank style='color:#2F92EE;'>#憩室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53789, encryptionId=14d853e8918, topicName=憩室)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=33b211483971, createdName=zutt, createdTime=Sat Dec 30 23:50:00 CST 2017, time=2017-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1523805, encodeId=31db152380557, content=<a href='/topic/show?id=7170e87563e' target=_blank style='color:#2F92EE;'>#结肠憩室炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78756, encryptionId=7170e87563e, topicName=结肠憩室炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4e5311558208, createdName=guojianrong, createdTime=Sat Dec 30 23:50:00 CST 2017, time=2017-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1585282, encodeId=6816158528252, content=<a href='/topic/show?id=aadf139959' target=_blank style='color:#2F92EE;'>#5-氨基水杨酸类药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1399, encryptionId=aadf139959, topicName=5-氨基水杨酸类药物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f21317152169, createdName=neurowu, createdTime=Sat Dec 30 23:50:00 CST 2017, time=2017-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=273498, encodeId=e60d2e3498e9, content=学习了.涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Fri Dec 29 12:00:14 CST 2017, time=2017-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=273475, encodeId=9ca92e347589, content=了解了解.学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Fri Dec 29 10:17:55 CST 2017, time=2017-12-29, status=1, ipAttribution=)]
    2017-12-29 1ddf0692m34(暂无匿称)

    学习了.涨知识

    0

  10. [GetPortalCommentsPageByObjectIdResponse(id=2072022, encodeId=d1e220e202287, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Sun Mar 18 18:50:00 CST 2018, time=2018-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1711319, encodeId=3f901e11319cc, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Thu Jan 04 20:50:00 CST 2018, time=2018-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1984048, encodeId=fab419840489e, content=<a href='/topic/show?id=e3f464183db' target=_blank style='color:#2F92EE;'>#水杨酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64183, encryptionId=e3f464183db, topicName=水杨酸)], attachment=null, authenticateStatus=null, createdAvatar=http://login.medsci.cn/upload/avatar/cc81592b507031e3cfd8d4c57911d98b/62c22832a9474aea1ca90ca058aebc03.jpg, createdBy=bed5446, createdName=limedical1974, createdTime=Wed Jan 24 00:50:00 CST 2018, time=2018-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1391441, encodeId=4d041391441e4, content=<a href='/topic/show?id=b5be53e91fc' target=_blank style='color:#2F92EE;'>#憩室炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53791, encryptionId=b5be53e91fc, topicName=憩室炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d4902500082, createdName=1249883fm12暂无昵称, createdTime=Sat Dec 30 23:50:00 CST 2017, time=2017-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1426962, encodeId=ee47142696297, content=<a href='/topic/show?id=221d685172' target=_blank style='color:#2F92EE;'>#EPA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6851, encryptionId=221d685172, topicName=EPA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4a9b4077760, createdName=gwc384, createdTime=Sat Dec 30 23:50:00 CST 2017, time=2017-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1522721, encodeId=077a1522e2158, content=<a href='/topic/show?id=14d853e8918' target=_blank style='color:#2F92EE;'>#憩室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53789, encryptionId=14d853e8918, topicName=憩室)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=33b211483971, createdName=zutt, createdTime=Sat Dec 30 23:50:00 CST 2017, time=2017-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1523805, encodeId=31db152380557, content=<a href='/topic/show?id=7170e87563e' target=_blank style='color:#2F92EE;'>#结肠憩室炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78756, encryptionId=7170e87563e, topicName=结肠憩室炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4e5311558208, createdName=guojianrong, createdTime=Sat Dec 30 23:50:00 CST 2017, time=2017-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1585282, encodeId=6816158528252, content=<a href='/topic/show?id=aadf139959' target=_blank style='color:#2F92EE;'>#5-氨基水杨酸类药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1399, encryptionId=aadf139959, topicName=5-氨基水杨酸类药物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f21317152169, createdName=neurowu, createdTime=Sat Dec 30 23:50:00 CST 2017, time=2017-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=273498, encodeId=e60d2e3498e9, content=学习了.涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Fri Dec 29 12:00:14 CST 2017, time=2017-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=273475, encodeId=9ca92e347589, content=了解了解.学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Fri Dec 29 10:17:55 CST 2017, time=2017-12-29, status=1, ipAttribution=)]
    2017-12-29 1dd8c52fm63(暂无匿称)

    了解了解.学习学习

    0

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