Baidu
map

Mol Metabol:饮食多样性降低或影响机体肠道微生物群落的多样性

2016-03-16 佚名 生物谷

过去50年里人类耕种方式的改变导致了农作物多样性的降低,从而导致人类饮食多样性的降低,而饮食丰富度的改变对人类健康的明显影响就是如今科学家们非常热衷于研究的课题;近日一项刊登于Molecular Metabolism杂志上的报告中,来自路易斯安那州立大学潘宁顿生物医学研究中心(Pennington Biomedical Research Center)的研究人员就阐明了他们的最新研究成果。

过去50年里人类耕种方式的改变导致了农作物多样性的降低,从而导致人类饮食多样性的降低,而饮食丰富度的改变对人类健康的明显影响就是如今科学家们非常热衷于研究的课题;近日一项刊登于Molecular Metabolism杂志上的报告中,来自路易斯安那州立大学潘宁顿生物医学研究中心(Pennington Biomedical Research Center)的研究人员就阐明了他们的最新研究成果。

研究者Heiman及其同事在文章中揭示了饮食多样性的降低如何改变人类肠道菌群的丰富度,研究者指出,健康个体机体中拥有多样性的肠道微生物群落,21世纪很多常见的疾病,比如2型糖尿病、肥胖及炎性肠病都和机体肠道微生物群落多样性降低直接相关。

肠道微生物可以作为内分泌器官一样发挥作用,代谢掉饮食中的特殊营养物并且产生特殊的物质来作为宿主机体的代谢信号,而高度特异性的饮食会随着时间慢慢改变机体肠道微生物组的“蓝图”模式;实际上,持续改变饮食几天就会明显改变肠道微生物的组成,而且如果饮食改变中涉及消除一种或多种大量的营养物,那么人类从本质上来讲就需要选择一些特殊的微生物来维持健康。

肠道微生物多样性的重要性并没有被夸大,其可以产生大量的重要分子来帮助宿主维持健康,并且增加宿主机体的自适应性以及生理性的反应,而且信号的组成越多,当饮食摄入被干扰后宿主机体维持自我平衡的可能性就越大。此外,由于每一种特殊的营养素都可以被微生物代谢成为特殊的代谢信号,因此信号改变的程度越大,宿主机体反应的改变就越大。

最后研究者表示,后期我们还将进行更为深入的研究来解释特殊的营养素如何影响肠道微生物组,同时揭示如何通过增加肠道微生物群落的多样性来帮助开发新型的疾病个体化疗法,比如一份简单的粪便样品或许就可以帮助医生们制定出特殊的个体饮食改变来帮助治疗相关代谢性疾病。

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (7)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1895889, encodeId=4d161895889dd, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Fri Oct 28 08:11:00 CST 2016, time=2016-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1824633, encodeId=2c72182463339, content=<a href='/topic/show?id=702a5065860' target=_blank style='color:#2F92EE;'>#微生物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50658, encryptionId=702a5065860, topicName=微生物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Sun Jun 05 00:11:00 CST 2016, time=2016-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1887513, encodeId=63be188e51334, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Sat Jul 16 18:11:00 CST 2016, time=2016-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1298830, encodeId=2e1d1298830a4, content=<a href='/topic/show?id=2088816e487' target=_blank style='color:#2F92EE;'>#肠道微生物群#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81674, encryptionId=2088816e487, topicName=肠道微生物群)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6e43278, createdName=yangjxjc, createdTime=Fri Mar 18 02:11:00 CST 2016, time=2016-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1367726, encodeId=9045136e72671, content=<a href='/topic/show?id=2cee50e22c6' target=_blank style='color:#2F92EE;'>#微生物群#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50722, encryptionId=2cee50e22c6, topicName=微生物群)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3609256, createdName=zhu_jun9837, createdTime=Fri Mar 18 02:11:00 CST 2016, time=2016-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1470901, encodeId=239114e09014b, content=<a href='/topic/show?id=507043296fe' target=_blank style='color:#2F92EE;'>#多样性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43296, encryptionId=507043296fe, topicName=多样性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2b6a7095267, createdName=neurosurgeon, createdTime=Fri Mar 18 02:11:00 CST 2016, time=2016-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1597948, encodeId=6664159e948fb, content=<a href='/topic/show?id=6c6f1e62c5' target=_blank style='color:#2F92EE;'>#ABO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1762, encryptionId=6c6f1e62c5, topicName=ABO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6c918580135, createdName=闆锋旦, createdTime=Fri Mar 18 02:11:00 CST 2016, time=2016-03-18, status=1, ipAttribution=)]
    2016-10-28 一闲
  2. [GetPortalCommentsPageByObjectIdResponse(id=1895889, encodeId=4d161895889dd, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Fri Oct 28 08:11:00 CST 2016, time=2016-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1824633, encodeId=2c72182463339, content=<a href='/topic/show?id=702a5065860' target=_blank style='color:#2F92EE;'>#微生物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50658, encryptionId=702a5065860, topicName=微生物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Sun Jun 05 00:11:00 CST 2016, time=2016-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1887513, encodeId=63be188e51334, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Sat Jul 16 18:11:00 CST 2016, time=2016-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1298830, encodeId=2e1d1298830a4, content=<a href='/topic/show?id=2088816e487' target=_blank style='color:#2F92EE;'>#肠道微生物群#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81674, encryptionId=2088816e487, topicName=肠道微生物群)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6e43278, createdName=yangjxjc, createdTime=Fri Mar 18 02:11:00 CST 2016, time=2016-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1367726, encodeId=9045136e72671, content=<a href='/topic/show?id=2cee50e22c6' target=_blank style='color:#2F92EE;'>#微生物群#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50722, encryptionId=2cee50e22c6, topicName=微生物群)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3609256, createdName=zhu_jun9837, createdTime=Fri Mar 18 02:11:00 CST 2016, time=2016-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1470901, encodeId=239114e09014b, content=<a href='/topic/show?id=507043296fe' target=_blank style='color:#2F92EE;'>#多样性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43296, encryptionId=507043296fe, topicName=多样性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2b6a7095267, createdName=neurosurgeon, createdTime=Fri Mar 18 02:11:00 CST 2016, time=2016-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1597948, encodeId=6664159e948fb, content=<a href='/topic/show?id=6c6f1e62c5' target=_blank style='color:#2F92EE;'>#ABO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1762, encryptionId=6c6f1e62c5, topicName=ABO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6c918580135, createdName=闆锋旦, createdTime=Fri Mar 18 02:11:00 CST 2016, time=2016-03-18, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1895889, encodeId=4d161895889dd, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Fri Oct 28 08:11:00 CST 2016, time=2016-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1824633, encodeId=2c72182463339, content=<a href='/topic/show?id=702a5065860' target=_blank style='color:#2F92EE;'>#微生物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50658, encryptionId=702a5065860, topicName=微生物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Sun Jun 05 00:11:00 CST 2016, time=2016-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1887513, encodeId=63be188e51334, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Sat Jul 16 18:11:00 CST 2016, time=2016-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1298830, encodeId=2e1d1298830a4, content=<a href='/topic/show?id=2088816e487' target=_blank style='color:#2F92EE;'>#肠道微生物群#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81674, encryptionId=2088816e487, topicName=肠道微生物群)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6e43278, createdName=yangjxjc, createdTime=Fri Mar 18 02:11:00 CST 2016, time=2016-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1367726, encodeId=9045136e72671, content=<a href='/topic/show?id=2cee50e22c6' target=_blank style='color:#2F92EE;'>#微生物群#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50722, encryptionId=2cee50e22c6, topicName=微生物群)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3609256, createdName=zhu_jun9837, createdTime=Fri Mar 18 02:11:00 CST 2016, time=2016-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1470901, encodeId=239114e09014b, content=<a href='/topic/show?id=507043296fe' target=_blank style='color:#2F92EE;'>#多样性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43296, encryptionId=507043296fe, topicName=多样性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2b6a7095267, createdName=neurosurgeon, createdTime=Fri Mar 18 02:11:00 CST 2016, time=2016-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1597948, encodeId=6664159e948fb, content=<a href='/topic/show?id=6c6f1e62c5' target=_blank style='color:#2F92EE;'>#ABO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1762, encryptionId=6c6f1e62c5, topicName=ABO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6c918580135, createdName=闆锋旦, createdTime=Fri Mar 18 02:11:00 CST 2016, time=2016-03-18, status=1, ipAttribution=)]
    2016-07-16 guojianrong
  4. [GetPortalCommentsPageByObjectIdResponse(id=1895889, encodeId=4d161895889dd, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Fri Oct 28 08:11:00 CST 2016, time=2016-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1824633, encodeId=2c72182463339, content=<a href='/topic/show?id=702a5065860' target=_blank style='color:#2F92EE;'>#微生物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50658, encryptionId=702a5065860, topicName=微生物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Sun Jun 05 00:11:00 CST 2016, time=2016-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1887513, encodeId=63be188e51334, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Sat Jul 16 18:11:00 CST 2016, time=2016-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1298830, encodeId=2e1d1298830a4, content=<a href='/topic/show?id=2088816e487' target=_blank style='color:#2F92EE;'>#肠道微生物群#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81674, encryptionId=2088816e487, topicName=肠道微生物群)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6e43278, createdName=yangjxjc, createdTime=Fri Mar 18 02:11:00 CST 2016, time=2016-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1367726, encodeId=9045136e72671, content=<a href='/topic/show?id=2cee50e22c6' target=_blank style='color:#2F92EE;'>#微生物群#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50722, encryptionId=2cee50e22c6, topicName=微生物群)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3609256, createdName=zhu_jun9837, createdTime=Fri Mar 18 02:11:00 CST 2016, time=2016-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1470901, encodeId=239114e09014b, content=<a href='/topic/show?id=507043296fe' target=_blank style='color:#2F92EE;'>#多样性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43296, encryptionId=507043296fe, topicName=多样性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2b6a7095267, createdName=neurosurgeon, createdTime=Fri Mar 18 02:11:00 CST 2016, time=2016-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1597948, encodeId=6664159e948fb, content=<a href='/topic/show?id=6c6f1e62c5' target=_blank style='color:#2F92EE;'>#ABO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1762, encryptionId=6c6f1e62c5, topicName=ABO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6c918580135, createdName=闆锋旦, createdTime=Fri Mar 18 02:11:00 CST 2016, time=2016-03-18, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1895889, encodeId=4d161895889dd, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Fri Oct 28 08:11:00 CST 2016, time=2016-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1824633, encodeId=2c72182463339, content=<a href='/topic/show?id=702a5065860' target=_blank style='color:#2F92EE;'>#微生物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50658, encryptionId=702a5065860, topicName=微生物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Sun Jun 05 00:11:00 CST 2016, time=2016-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1887513, encodeId=63be188e51334, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Sat Jul 16 18:11:00 CST 2016, time=2016-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1298830, encodeId=2e1d1298830a4, content=<a href='/topic/show?id=2088816e487' target=_blank style='color:#2F92EE;'>#肠道微生物群#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81674, encryptionId=2088816e487, topicName=肠道微生物群)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6e43278, createdName=yangjxjc, createdTime=Fri Mar 18 02:11:00 CST 2016, time=2016-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1367726, encodeId=9045136e72671, content=<a href='/topic/show?id=2cee50e22c6' target=_blank style='color:#2F92EE;'>#微生物群#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50722, encryptionId=2cee50e22c6, topicName=微生物群)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3609256, createdName=zhu_jun9837, createdTime=Fri Mar 18 02:11:00 CST 2016, time=2016-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1470901, encodeId=239114e09014b, content=<a href='/topic/show?id=507043296fe' target=_blank style='color:#2F92EE;'>#多样性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43296, encryptionId=507043296fe, topicName=多样性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2b6a7095267, createdName=neurosurgeon, createdTime=Fri Mar 18 02:11:00 CST 2016, time=2016-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1597948, encodeId=6664159e948fb, content=<a href='/topic/show?id=6c6f1e62c5' target=_blank style='color:#2F92EE;'>#ABO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1762, encryptionId=6c6f1e62c5, topicName=ABO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6c918580135, createdName=闆锋旦, createdTime=Fri Mar 18 02:11:00 CST 2016, time=2016-03-18, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1895889, encodeId=4d161895889dd, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Fri Oct 28 08:11:00 CST 2016, time=2016-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1824633, encodeId=2c72182463339, content=<a href='/topic/show?id=702a5065860' target=_blank style='color:#2F92EE;'>#微生物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50658, encryptionId=702a5065860, topicName=微生物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Sun Jun 05 00:11:00 CST 2016, time=2016-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1887513, encodeId=63be188e51334, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Sat Jul 16 18:11:00 CST 2016, time=2016-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1298830, encodeId=2e1d1298830a4, content=<a href='/topic/show?id=2088816e487' target=_blank style='color:#2F92EE;'>#肠道微生物群#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81674, encryptionId=2088816e487, topicName=肠道微生物群)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6e43278, createdName=yangjxjc, createdTime=Fri Mar 18 02:11:00 CST 2016, time=2016-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1367726, encodeId=9045136e72671, content=<a href='/topic/show?id=2cee50e22c6' target=_blank style='color:#2F92EE;'>#微生物群#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50722, encryptionId=2cee50e22c6, topicName=微生物群)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3609256, createdName=zhu_jun9837, createdTime=Fri Mar 18 02:11:00 CST 2016, time=2016-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1470901, encodeId=239114e09014b, content=<a href='/topic/show?id=507043296fe' target=_blank style='color:#2F92EE;'>#多样性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43296, encryptionId=507043296fe, topicName=多样性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2b6a7095267, createdName=neurosurgeon, createdTime=Fri Mar 18 02:11:00 CST 2016, time=2016-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1597948, encodeId=6664159e948fb, content=<a href='/topic/show?id=6c6f1e62c5' target=_blank style='color:#2F92EE;'>#ABO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1762, encryptionId=6c6f1e62c5, topicName=ABO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6c918580135, createdName=闆锋旦, createdTime=Fri Mar 18 02:11:00 CST 2016, time=2016-03-18, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1895889, encodeId=4d161895889dd, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Fri Oct 28 08:11:00 CST 2016, time=2016-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1824633, encodeId=2c72182463339, content=<a href='/topic/show?id=702a5065860' target=_blank style='color:#2F92EE;'>#微生物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50658, encryptionId=702a5065860, topicName=微生物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Sun Jun 05 00:11:00 CST 2016, time=2016-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1887513, encodeId=63be188e51334, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Sat Jul 16 18:11:00 CST 2016, time=2016-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1298830, encodeId=2e1d1298830a4, content=<a href='/topic/show?id=2088816e487' target=_blank style='color:#2F92EE;'>#肠道微生物群#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81674, encryptionId=2088816e487, topicName=肠道微生物群)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6e43278, createdName=yangjxjc, createdTime=Fri Mar 18 02:11:00 CST 2016, time=2016-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1367726, encodeId=9045136e72671, content=<a href='/topic/show?id=2cee50e22c6' target=_blank style='color:#2F92EE;'>#微生物群#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50722, encryptionId=2cee50e22c6, topicName=微生物群)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3609256, createdName=zhu_jun9837, createdTime=Fri Mar 18 02:11:00 CST 2016, time=2016-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1470901, encodeId=239114e09014b, content=<a href='/topic/show?id=507043296fe' target=_blank style='color:#2F92EE;'>#多样性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43296, encryptionId=507043296fe, topicName=多样性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2b6a7095267, createdName=neurosurgeon, createdTime=Fri Mar 18 02:11:00 CST 2016, time=2016-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1597948, encodeId=6664159e948fb, content=<a href='/topic/show?id=6c6f1e62c5' target=_blank style='color:#2F92EE;'>#ABO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1762, encryptionId=6c6f1e62c5, topicName=ABO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6c918580135, createdName=闆锋旦, createdTime=Fri Mar 18 02:11:00 CST 2016, time=2016-03-18, status=1, ipAttribution=)]
    2016-03-18 闆锋旦

相关资讯

EMBO Rep:调节棕色脂肪产热的分子有望成为肥胖治疗新靶点

棕色脂肪组织是负责哺乳动物非战栗性产热的一个主要部位,许多科学家将其视作预防和治疗肥胖的靶点。最近一项研究发现钙离子通道TRPV2在小鼠的棕色脂肪产热过程中发挥重要调节作用,缺少TRPV2会损伤小鼠棕色脂肪组织的非战栗性产热过程。TRPV2虽然在调节许多细胞功能方面发挥着重要作用,但该研究首次发现了其在棕色脂肪细胞产热功能方面的作用。相关研究结

沪亚生物国际获复旦大学免疫肿瘤药品专利权——IDO抑制剂被开发用于肿瘤治疗

作为中国原创新型生物医药全球化共同开发的领军企业,HUYA生物国际(HUYA)于今天正式宣布与复旦大学签订了一项由复旦研究人员发现的新型免疫肿瘤候选药物的独家专利许可,可拥有该免疫肿瘤候选药物除中国地区之外的全球专利权益。该药物是由复旦大学生命科学院杨青教授课题组历经十余年研发的吲哚胺-2,3-双加氧酶(IDO)新型抑制剂。研究表明?IDO途径在抑制T细胞功能中起重要作用,从而使肿瘤逃避免疫监

退休会给我们带来哪些好处

现在,国内提出渐进式延迟退休年龄,到2030年实现男性职工和居民65岁领取养老金。人社部称"渐进式"延迟退休年龄,对个人影响不明显这一论断可能需要我们重新去做评价。 最近一篇发表在American Journal of Preventive Medicine的研究发现,退休会让生活方式变得更积极健康。来自悉尼大学的这一项具有里程碑意义的研究发现:当人们退休后,他们的生活会变得更活跃、睡眠更好、而

JAD:呼吁科研工作者关注微生物可能是引发老年痴呆的原因

在JAD杂志中发表一篇文章中,超过30名研究人员和临床医生认为,越来越多的研究给我们暗示微生物可能是引发阿兹海默症(AD)的主要病因。尽管,很多证据开始显示出针对微生物的治疗会减缓和阻止AD等神经退行性疾病的恶化。而关于这一方面的研究却被现在关于AD的"主流研究"所掩盖。现在,是时候让我们开始重新评估微生物感染可能是一些神经退行性疾病的主要病因,或至少为原因之一。 他们在文章中特别提到了三种微生

J Neurosci :用极度饥饿的方式可预防神经退行性变

减少一个人的卡路里摄入量可以预防神经退行性疾病,如帕金森病。但这种现象发生的原因直到现在仍然是个谜。 莫纳什大学生物医学研究所的研究人员Zane Andrews副教授发现这种热量可降低神经保护作用——开放该类药物发展可以在不用减少卡路里摄入的情况下可减缓或防止帕金森等疾病。该研究发表在《神经科学杂志》上。 人类有一种激素称为胃促生长素或“饥饿激素”——在胃肠道产生,作用于大脑用以调节饥饿的

lapatinib以及trastuzumab组合可以11天内消灭特定乳腺癌

利用两种药物组合治疗,能够在11天内抑制或者消灭特定类型的乳腺癌。 相关结果发表在于阿姆斯特丹召开的“欧洲乳腺癌会议上”。这些结果表明:对于一些女性来说,新的治疗方法能够代替目前使用的常规化学疗法。 该药物组合能够靶向HER2蛋白,带蛋白在乳腺癌细胞中出现的几率为10%。HER2阳性的乳腺癌具有恶化程度高以及耐药性强的特点。 该方法的优点在于,它可以起到完全消除肿瘤细胞的作用,而且从诊断到

Baidu
map
Baidu
map
Baidu
map