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BMJ:青春期和成年早期多吃水果和蔬菜可大大降低乳腺癌风险

2016-05-12 崔倩 译 MedSci原创

该研究的目的是评估青春期和成年早期摄取水果和蔬菜与和乳腺癌风险之间的关系。原始出处:Maryam S Farvid,Wendy Y Chen,Karin B Michels, et al.Fruit and vegetable consumption in adolescence and early adulthood and risk of breast cancer,BMJ,2016.5.12

该研究的目的是在青春期和成年早期女性人群中,评估水果和蔬菜的摄入与和乳腺癌风险之间的关系。

来自美国的研究人员进行了一项前瞻性队列研究。该研究纳入了90476名绝经前女性,年龄27-44岁,这些女性来自于护士健康研究II,她们在1991年时完成了一份关于饮食的调查问卷。在1998年时,这些女性中的44233名参与者完成了青春期饮食调查问卷。

该研究的主要检测指标为浸润性乳腺癌新发病例,通过自我报告确定和病理报告证实。

从随访时期到2013年,共有3235例浸润性乳腺癌病例发生。在这些病例中,1347例患者是那些已经完成了青春期(13-18岁)饮食调查问卷的女性。青春期总水果消耗量与乳腺癌的风险降低有关。最高摄入量(平均摄入2.9份/天)与 最低摄入量的五分之一(平均摄入0.5份/天)相比危险比为0.75(95%置信区间0.62至0.90; 趋势P=0.01)。青少年期水果摄入量与成人水果摄入量无关。风险和成年早期的总水果摄入量,以及青春期或成年早期总的蔬菜摄入量之间没有关系。成年早期摄入含有丰富胡萝卜素α的水果和蔬菜可降低绝经前乳腺癌的风险。最高(平均摄入量0.5份/天)与最低摄入量的五分之一(平均摄入量0.03份/天)相比危险比为0.82(0.70至0.96)。青春期水果摄入量与雌激素与孕激素受体阴性肿瘤的相关性要大于其与孕激素受体阳性肿瘤的相关性(异质性P=0.02),且其与二者的相关性均较显著。对于个别水果和蔬菜,在成年早期大量摄入苹果,香蕉,葡萄和橘子以及羽衣甘蓝可显著降低乳腺癌的风险。青春期或成年早期的果汁摄入量与风险无关。

摄入较多的水果可降低乳腺癌的风险。青春期的食物选择也变得非常重要。

原始出处:

Maryam S Farvid,Wendy Y Chen,Karin B Michels, et al.Fruit and vegetable consumption in adolescence and early adulthood and risk of breast cancer,BMJ,2016.5.12

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    2016-11-22 sjq027
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    2016-09-11 1e10c84am36(暂无匿称)

    好文章,百姓也能从中学到好多医学知识

    0

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    2017-01-04 gaoxiaoe
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