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Lancet:COVID-19导致的全球抑郁症和焦虑症的流行率和负担分析

2021-11-06 MedSci原创 MedSci原创

精神障碍是造成全球健康相关负担的主要原因,其中抑郁症和焦虑症是造成这一负担的主要因素。

精神障碍是造成全球健康相关负担的主要原因,其中抑郁症和焦虑症是造成这一负担的主要因素。COVID-19大流行病的出现创造了一个环境,使不良心理健康的许多决定因素变得更加严重。

当务之急是需要关于COVID-19对心理健康影响的最新信息,以便为卫生系统的反应提供参考。最近一项研究中,国际COVID-19心理健康协作组织旨在量化COVID-19大流行病对2020年全球主要抑郁症和焦虑症的流行率和负担的影响。结果发表在Lancet杂志上。

研究人员对2020年1月1日-2021年1月29日期间发表的报告COVID-19大流行期间主要抑郁症和焦虑症患病率的数据进行了系统回顾。搜索了PubMed、Google Scholar,随后将收集到的数据用于元回归,通过COVID-19的影响指标(人员流动、每日SARS-CoV-2感染率和每日超额死亡率)估计大流行前和大流行中期(使用每个研究定义的时期)的主要抑郁症和焦虑症的流行率变化。然后用这个模型来估计按年龄、性别和地点的变化大流行前的流行率。使用最终的患病率估计值和残疾权重来估计主要抑郁症和焦虑症的残疾生活年数和残疾调整生命年数(DALYs)。

最终确定了5683个独特的数据源,其中48个符合纳入标准(46个研究符合主要抑郁症的标准,27个符合焦虑症的标准)。两项COVID-19影响指标,特别是每日SARS-CoV-2感染率和人员流动的减少,与严重抑郁症患病率的增加有关(B=0.9[95%CI: 0.1-1.8,每日SARS-CoV-2感染为18.1[7.9-28.3])和焦虑症(0.9[0.1-1.7]和13.8[10.7-17.0])。

同时,女性比男性受大流行病的影响更大、年轻群体比老年群体受影响更大。研究人员估计,在2020年受大流行病打击最严重的地区,根据人类流动性减少和每日SARS-CoV-2感染率来衡量,抑郁症和焦虑症的患病率增加最多。

COVID-19大流行前和流行中精神障碍的流行率

由于COVID-19大流行,全球将增加5300万例重度抑郁症患者(增加27.6%),全球焦虑症病例增加了76-200万(增加了25.6%)。总的来说,2020年,主要抑郁症在全球造成494万DALYs,焦虑症造成445万DALYs。

综上,COVID-19大流行病使大多数国家更加迫切地需要加强心理健康系统。

 

参考文献:

Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic. https://doi.org/10.1016/S0140-6736(21)02143-7

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    2022-05-06 howi
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    2022-10-07 lixiaol
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    2021-11-07 我思故我在2

    又学到了新知识

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    2021-11-07 学医无涯

    学习一下

    0

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    2021-11-07 ms9000001258055198

    学习了

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    2021-11-06 121bb8d4m13暂无昵称

    学习

    0

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焦虑症是常见的心理健康问题,通常发生在生命早期,包括童年、青春期或成年早期。研究人员发现,焦虑症影响着世界上大约10%的人口,且女性患病率是男性的2倍。

JAMA Psychiatry: 有氧运动或艾司西酞普兰治疗冠心病焦虑患者

艾司西酞普兰对患有冠心病的焦虑患者是安全有效的,同时有氧运动对改善冠心病患者焦虑有益

JNNP:患有焦虑症的儿童和青少年的脑震荡症状和康复

脑震荡,通常也称为轻度脑外伤(mTBI),是美国主要的公共卫生问题。每年估计有超过一半的百万分之一儿童在急诊室接受脑震荡治疗。虽然大多数受伤的儿童和青少年的症状通常在4周内消失,但25%至40%的经验

Complement Ther Med:饮用薰衣草花草茶可以减少老年人的抑郁和焦虑

世界各地老年人抑郁症和焦虑症的发病率逐渐上升。有学者认为薰衣草可以稳定人们的情绪,为验证此观点,研究人员进行了一项单盲临床试验,旨在评估薰衣草对老年人的焦虑和抑郁的影响,研究结果已发表于Complem

Acta Psychiatrica Scandinavica:代谢组学谱可用于区分焦虑症和抑郁症

炎症和动脉粥样硬化代谢组谱可能与抑郁的存在唯一相关,而与焦虑无关。代谢组特征可能是这些高度相关但又不相同的情绪状态的一个显著特征。

JAMA Psychiatry:当心!冠心病患者可能得了“双心病”!

艾司西酞普兰治疗焦虑对减少冠心病患者的焦虑是安全和有效的。

拓展阅读

【今日分享】青少年精神障碍住院病人自伤预防的证据总结

总结有关青少年精神障碍住院病人自伤预防的最佳证据可为临床医护人员制订相关管理方案和开展临床实践提供参考,建议在证据应用基础上结合具体临床情景和病人意愿制订个体化方案。

JAMA+Cell:精神障碍成为儿童和青少年非致命残疾的主要原因

阐述儿童青少年精神障碍的全球普遍性与严重性,聚焦中国现状,介绍该群体精神障碍用药,强调其对健康的重大影响及应对紧迫性。

Translational Psychiatry:利用大型临床生物银行开发抽动障碍的表型风险评分

本研究通过电子健康记录识别出69种与抽动障碍显著相关的表型,生成的表型风险评分在临床验证的抽动障碍病例中显著较高,验证了其在识别复杂表型障碍个体方面的有效性。

International Journal of Mental Health and Addiction:预测共病障碍的交叉因素:决策树模型

参与康复是最关键的预测因素,法律参与、决策困难、父母/照顾者角色和自我伤害行为也是重要预测因素。年龄、性别、种族/民族和疫情年份未显示出与共病障碍的统计显著关联。

Nat Commun:浙江中医药大学陈忠团队发现减轻恐惧导致的心理疾病的新靶点

该研究表明删除内侧隔(MS)中的H1R基因而不是其他胆碱能神经元,能够差异激活小鼠齿状回(DG)神经元,特异性增强情境恐惧记忆,但不影响线索记忆。

Psychiatry Research: 儿童和青少年精神障碍的多基因风险评分

大多数儿童和青少年精神科医生认为目前多基因风险评分在临床上效用有限,但对其未来应用持谨慎乐观态度。他们强调,要进一步研究PRS的准确性、预测性和临床效用,并制定明确的临床指南,以确保PRS的负责任使用

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