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EOS 2016:成人缺血性脑卒中与儿童期BMI有关

2016-06-04 Seven L MedSci原创

瑞典哥德堡欧洲肥胖峰会提出的研究指出,男性和女性童年期间高BMI和BMI增加,与早期(25-55岁)缺血性脑卒中风险升高有关。儿童期BMI增加只与女性晚期(>55岁)缺血性脑卒中风险升高有关,与男性无关。“成人BMI与缺血性脑卒中有关,尤其是年轻人,但是儿童期BMI与成人缺血性脑卒中之间的关系尚不清楚,”丹麦哥本哈根大学医学与健康科学学院诺和诺德基金会中心的Line Klingen Haugaar

瑞典哥德堡欧洲肥胖峰会提出的研究指出,男性和女性童年期间高BMI和BMI增加,与早期(25-55岁)缺血性脑卒中风险升高有关。儿童期BMI增加只与女性晚期(>55岁)缺血性脑卒中风险升高有关,与男性无关。

“成人BMI与缺血性脑卒中有关,尤其是年轻人,但是儿童期BMI与成人缺血性脑卒中之间的关系尚不清楚,”丹麦哥本哈根大学医学与健康科学学院诺和诺德基金会中心的Line Klingen Haugaard博士和他的同事们写道。

Haugaard和同事对307677名参与者进行了评估,在他们7岁、10岁或13岁时测量身高体重,以探究童年BMI、BMI增加与早期和晚期成人缺血性卒中风险的相关性。研究随访8128058人年。

总体而言,3529名女性和5370名男性在随访期间发生了缺血性脑卒中。儿童期BMI z值高于平均时,早起缺血性脑卒中风险增加,但是晚期卒中风险与之无关。

在儿童各年龄段,与早期缺血性脑卒中相关联系是相似的,但是在13岁时候联系最强,BMI z评分每增加1,女性和男性卒中HR增加1.26 (95% CI, 1.11-1.43)和1.21 (95% CI, 1.1-1.33)。7-13岁 时,BMI z评分每增加1,女性和男性卒中HR增加1.26; 95% CI, 1.13-1.42;和1.2; 95% CI, 1.09-1.32。而晚期缺血性卒中只在女性增加(HR = 1.1; 95% CI, 1.03-1.17)。

研究人员写道,“这项研究的结果强调了儿童超重和肥胖对动脉粥样硬化早期发展的影响,正如高血压和2型糖尿病等缺血性卒中危险因素一样。”

原始出处:

Haugaard LK, et al. PP2.02. Presented at: European Obesity Summit; June 1-4, 2016; Gothenburg, Sweden.

BMI gains during childhood may increase ischemic stroke risk.Healio.June 3, 2016

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    2016-08-16 huiminghappy

    减肥要从小做起!

    0

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    2016-06-07 黑心天使

    孩子还是不能吃太多

    0

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