Baidu
map

颈前路后纵韧带骨化切除术脑脊液漏发生率高

2012-11-16 Jane摘编 医学论坛网

  上海长征医院脊柱外科的一项研究表明,颈椎后纵韧带骨化症(OPLL)患者行颈前路手术术中易发生硬脊膜损伤,术中一期修复极为困难,术后脑脊液漏发生率高,应采取综合措施处理,以获痊愈。该论文发表在2012年第10期《中国脊柱脊椎杂志》。   该研究选取2008年1月~2012年1月采用颈前路后纵韧带骨化切除术治疗颈椎OPLL患者126例,男89例,女37例;年龄平均61岁;病程平均4.2年。骨化物

  上海长征医院脊柱外科的一项研究表明,颈椎后纵韧带骨化症(OPLL)患者行颈前路手术术中易发生硬脊膜损伤,术中一期修复极为困难,术后脑脊液漏发生率高,应采取综合措施处理,以获痊愈。该论文发表在2012年第10期《中国脊柱脊椎杂志》。

  该研究选取2008年1月~2012年1月采用颈前路后纵韧带骨化切除术治疗颈椎OPLL患者126例,男89例,女37例;年龄平均61岁;病程平均4.2年。骨化物在矢状面上范围涉及1~3个椎体。术中发现11例患者合并硬脊膜骨化,其中7例术中发生硬脊膜破损(4例为硬脊膜撕裂,3例形成硬脊膜缺损);115例未合并硬脊膜骨化患者中,4例发生硬脊膜撕裂。术中均采用明胶海绵覆盖及生物蛋白胶封堵,术后采用常压引流、卧床休息、预防感染及营养支持等方法综合处理,观察患者脑脊液漏情况及转归。

  结果是,11例术中硬脊膜破损的患者术后均发生脑脊液漏,脑脊液漏发生率为8.7%(11/126),其中合并硬脊膜骨化患者术后脑脊液漏发生率为63.6%(7/11),未合并硬脊膜骨化患者术后脑脊液漏发生率为0.03%(4/115),两组比较差异有统计学意义(P<0.001)。经综合处理后,3例于术后3~5d内痊愈;8例患者切口愈合拔管后形成间隙性脑脊液囊肿,经反复穿刺抽吸、颈部环形加压包扎治疗,均于术后14~30d内痊愈,其中1例合并颅内感染,经腰大池置管持续引流加鞘内注射抗生素治疗痊愈。11例患者均获随访,随访时间平均12.8个月,无神经症状加重及持续性头痛等后遗症发生,术后平均神经功能改善率为51.2%。



版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1876628, encodeId=377a18e6628d7, content=<a href='/topic/show?id=67c5319121e' target=_blank style='color:#2F92EE;'>#切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31912, encryptionId=67c5319121e, topicName=切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d8a96, createdName=doctorzheng, createdTime=Wed Apr 17 12:08:00 CST 2013, time=2013-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1826209, encodeId=96dd182620921, content=<a href='/topic/show?id=e5283e89970' target=_blank style='color:#2F92EE;'>#发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37899, encryptionId=e5283e89970, topicName=发生率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Sun Jun 16 03:08:00 CST 2013, time=2013-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2071067, encodeId=5ad820e106772, content=<a href='/topic/show?id=adac391010b' target=_blank style='color:#2F92EE;'>#后纵韧带#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39101, encryptionId=adac391010b, topicName=后纵韧带)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45b2276, createdName=839640778, createdTime=Sun Jan 13 05:08:00 CST 2013, time=2013-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1507379, encodeId=f8ec150e37999, content=<a href='/topic/show?id=16b7100010c7' target=_blank style='color:#2F92EE;'>#韧带#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100010, encryptionId=16b7100010c7, topicName=韧带)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d9b19890064, createdName=juliusluan81, createdTime=Sun Nov 18 06:08:00 CST 2012, time=2012-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1597085, encodeId=c21b159e085e9, content=<a href='/topic/show?id=0968850356f' target=_blank style='color:#2F92EE;'>#脑脊液漏#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85035, encryptionId=0968850356f, topicName=脑脊液漏)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a6b618479697, createdName=gds2015, createdTime=Sun Nov 18 06:08:00 CST 2012, time=2012-11-18, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1876628, encodeId=377a18e6628d7, content=<a href='/topic/show?id=67c5319121e' target=_blank style='color:#2F92EE;'>#切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31912, encryptionId=67c5319121e, topicName=切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d8a96, createdName=doctorzheng, createdTime=Wed Apr 17 12:08:00 CST 2013, time=2013-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1826209, encodeId=96dd182620921, content=<a href='/topic/show?id=e5283e89970' target=_blank style='color:#2F92EE;'>#发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37899, encryptionId=e5283e89970, topicName=发生率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Sun Jun 16 03:08:00 CST 2013, time=2013-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2071067, encodeId=5ad820e106772, content=<a href='/topic/show?id=adac391010b' target=_blank style='color:#2F92EE;'>#后纵韧带#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39101, encryptionId=adac391010b, topicName=后纵韧带)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45b2276, createdName=839640778, createdTime=Sun Jan 13 05:08:00 CST 2013, time=2013-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1507379, encodeId=f8ec150e37999, content=<a href='/topic/show?id=16b7100010c7' target=_blank style='color:#2F92EE;'>#韧带#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100010, encryptionId=16b7100010c7, topicName=韧带)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d9b19890064, createdName=juliusluan81, createdTime=Sun Nov 18 06:08:00 CST 2012, time=2012-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1597085, encodeId=c21b159e085e9, content=<a href='/topic/show?id=0968850356f' target=_blank style='color:#2F92EE;'>#脑脊液漏#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85035, encryptionId=0968850356f, topicName=脑脊液漏)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a6b618479697, createdName=gds2015, createdTime=Sun Nov 18 06:08:00 CST 2012, time=2012-11-18, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1876628, encodeId=377a18e6628d7, content=<a href='/topic/show?id=67c5319121e' target=_blank style='color:#2F92EE;'>#切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31912, encryptionId=67c5319121e, topicName=切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d8a96, createdName=doctorzheng, createdTime=Wed Apr 17 12:08:00 CST 2013, time=2013-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1826209, encodeId=96dd182620921, content=<a href='/topic/show?id=e5283e89970' target=_blank style='color:#2F92EE;'>#发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37899, encryptionId=e5283e89970, topicName=发生率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Sun Jun 16 03:08:00 CST 2013, time=2013-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2071067, encodeId=5ad820e106772, content=<a href='/topic/show?id=adac391010b' target=_blank style='color:#2F92EE;'>#后纵韧带#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39101, encryptionId=adac391010b, topicName=后纵韧带)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45b2276, createdName=839640778, createdTime=Sun Jan 13 05:08:00 CST 2013, time=2013-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1507379, encodeId=f8ec150e37999, content=<a href='/topic/show?id=16b7100010c7' target=_blank style='color:#2F92EE;'>#韧带#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100010, encryptionId=16b7100010c7, topicName=韧带)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d9b19890064, createdName=juliusluan81, createdTime=Sun Nov 18 06:08:00 CST 2012, time=2012-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1597085, encodeId=c21b159e085e9, content=<a href='/topic/show?id=0968850356f' target=_blank style='color:#2F92EE;'>#脑脊液漏#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85035, encryptionId=0968850356f, topicName=脑脊液漏)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a6b618479697, createdName=gds2015, createdTime=Sun Nov 18 06:08:00 CST 2012, time=2012-11-18, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1876628, encodeId=377a18e6628d7, content=<a href='/topic/show?id=67c5319121e' target=_blank style='color:#2F92EE;'>#切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31912, encryptionId=67c5319121e, topicName=切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d8a96, createdName=doctorzheng, createdTime=Wed Apr 17 12:08:00 CST 2013, time=2013-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1826209, encodeId=96dd182620921, content=<a href='/topic/show?id=e5283e89970' target=_blank style='color:#2F92EE;'>#发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37899, encryptionId=e5283e89970, topicName=发生率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Sun Jun 16 03:08:00 CST 2013, time=2013-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2071067, encodeId=5ad820e106772, content=<a href='/topic/show?id=adac391010b' target=_blank style='color:#2F92EE;'>#后纵韧带#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39101, encryptionId=adac391010b, topicName=后纵韧带)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45b2276, createdName=839640778, createdTime=Sun Jan 13 05:08:00 CST 2013, time=2013-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1507379, encodeId=f8ec150e37999, content=<a href='/topic/show?id=16b7100010c7' target=_blank style='color:#2F92EE;'>#韧带#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100010, encryptionId=16b7100010c7, topicName=韧带)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d9b19890064, createdName=juliusluan81, createdTime=Sun Nov 18 06:08:00 CST 2012, time=2012-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1597085, encodeId=c21b159e085e9, content=<a href='/topic/show?id=0968850356f' target=_blank style='color:#2F92EE;'>#脑脊液漏#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85035, encryptionId=0968850356f, topicName=脑脊液漏)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a6b618479697, createdName=gds2015, createdTime=Sun Nov 18 06:08:00 CST 2012, time=2012-11-18, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1876628, encodeId=377a18e6628d7, content=<a href='/topic/show?id=67c5319121e' target=_blank style='color:#2F92EE;'>#切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31912, encryptionId=67c5319121e, topicName=切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d8a96, createdName=doctorzheng, createdTime=Wed Apr 17 12:08:00 CST 2013, time=2013-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1826209, encodeId=96dd182620921, content=<a href='/topic/show?id=e5283e89970' target=_blank style='color:#2F92EE;'>#发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37899, encryptionId=e5283e89970, topicName=发生率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Sun Jun 16 03:08:00 CST 2013, time=2013-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2071067, encodeId=5ad820e106772, content=<a href='/topic/show?id=adac391010b' target=_blank style='color:#2F92EE;'>#后纵韧带#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39101, encryptionId=adac391010b, topicName=后纵韧带)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45b2276, createdName=839640778, createdTime=Sun Jan 13 05:08:00 CST 2013, time=2013-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1507379, encodeId=f8ec150e37999, content=<a href='/topic/show?id=16b7100010c7' target=_blank style='color:#2F92EE;'>#韧带#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100010, encryptionId=16b7100010c7, topicName=韧带)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d9b19890064, createdName=juliusluan81, createdTime=Sun Nov 18 06:08:00 CST 2012, time=2012-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1597085, encodeId=c21b159e085e9, content=<a href='/topic/show?id=0968850356f' target=_blank style='color:#2F92EE;'>#脑脊液漏#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85035, encryptionId=0968850356f, topicName=脑脊液漏)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a6b618479697, createdName=gds2015, createdTime=Sun Nov 18 06:08:00 CST 2012, time=2012-11-18, status=1, ipAttribution=)]
Baidu
map
Baidu
map
Baidu
map