Baidu
map

治疗糖尿病,不要忘记使用他汀

2016-06-20 郭艺芳心前沿 郭艺芳心前沿

对于糖尿病患者,不应仅仅关注降糖。动脉粥样硬化性心血管疾病(如冠心病、心肌梗死与脑梗死等)是糖尿病患者致死致残的主要原因,有效防治大血管病变才是治疗糖尿病的最终目标。为达此目的,一方面要合理的控制血糖,同时要积极控制血压并根据患者具体情况应用他汀降低胆固醇水平。哪些糖尿病患者需要接受他汀治疗?所有确诊动脉粥样硬化性心血管疾病(冠心病、缺血性卒中、外周动脉疾病[如预动脉或下肢动脉狭窄超过50%]等)

对于糖尿病患者,不应仅仅关注降糖。动脉粥样硬化性心血管疾病(如冠心病、心肌梗死与脑梗死等)是糖尿病患者致死致残的主要原因,有效防治大血管病变才是治疗糖尿病的最终目标。为达此目的,一方面要合理的控制血糖,同时要积极控制血压并根据患者具体情况应用他汀降低胆固醇水平。


哪些糖尿病患者需要接受他汀治疗?


所有确诊动脉粥样硬化性心血管疾病(冠心病、缺血性卒中、外周动脉疾病[如预动脉或下肢动脉狭窄超过50%]等)的患者,无论其胆固醇是否增高,均应长期应用他汀治疗,并将低密度脂蛋白胆固醇(LDL-C)降低至<1.8mmol/L;


未合并心血管病者,首先要根据其否存在其他心血管危险因素确定LDL-C的目标值,若患者LDL-C水平超过此目标值则应予以他汀治疗。不同糖尿病患者的LDL-C目标值如下:


1)合并至少一项其他危险因素(男≥45岁,女≥55,高血压,吸烟,HDL-C<1.04mmo/L,体质指数≥28Kg/m2,早发缺血性心血管病家族史),LDL-C目标值<1.8mmo/L;


2)不伴其他危险因素,LDL-C目标值<2.6mmo/L。


特别强调


糖尿病患者最常见的血脂紊乱是甘油三酯增高或高密度脂蛋白胆固醇降低,但这并不意味着应该应用贝特类或烟酸类药物对此进行干预。如果甘油三酯严重增高(≥5.6 mmol/L)可首选贝特治疗。其他患者均应将他汀作为首选的降脂药,降低胆固醇水平是最重要的治疗目标。

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=132108, encodeId=0a27132108f7, content=文章很好,非常有益, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Sep 21 08:26:00 CST 2016, time=2016-09-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=125791, encodeId=1edf125e9183, content=感谢分享,临床上很实用, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160907/IMG57D00CF1965701770.jpg, createdBy=565c1948251, createdName=舒心和人, createdTime=Tue Sep 13 22:30:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=91412, encodeId=ca0b91412e8, content=期待后续报道, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuK9CDibOwszLoEBg36ZXqzB5NDasNV9GTfFDmBicM1V8hUS4OtTicG3IiaFIKq4wqD23LUxORRJXqjVs/0, createdBy=00e81647535, createdName=I come, createdTime=Tue Jun 28 08:23:00 CST 2016, time=2016-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=91337, encodeId=61f99133eb6, content=他丁类药物真的很重要, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=a37a1710612, createdName=oo902, createdTime=Mon Jun 27 16:24:00 CST 2016, time=2016-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=91068, encodeId=0c3791068a0, content=降脂的他丁药是跟降糖药一起终生吃吗?怕吃久了对肝功能有影响, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cfb791835, createdName=CHBLY, createdTime=Sat Jun 25 03:39:00 CST 2016, time=2016-06-25, status=1, ipAttribution=)]
    2016-09-21 1e10c84am36(暂无匿称)

    文章很好,非常有益

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=132108, encodeId=0a27132108f7, content=文章很好,非常有益, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Sep 21 08:26:00 CST 2016, time=2016-09-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=125791, encodeId=1edf125e9183, content=感谢分享,临床上很实用, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160907/IMG57D00CF1965701770.jpg, createdBy=565c1948251, createdName=舒心和人, createdTime=Tue Sep 13 22:30:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=91412, encodeId=ca0b91412e8, content=期待后续报道, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuK9CDibOwszLoEBg36ZXqzB5NDasNV9GTfFDmBicM1V8hUS4OtTicG3IiaFIKq4wqD23LUxORRJXqjVs/0, createdBy=00e81647535, createdName=I come, createdTime=Tue Jun 28 08:23:00 CST 2016, time=2016-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=91337, encodeId=61f99133eb6, content=他丁类药物真的很重要, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=a37a1710612, createdName=oo902, createdTime=Mon Jun 27 16:24:00 CST 2016, time=2016-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=91068, encodeId=0c3791068a0, content=降脂的他丁药是跟降糖药一起终生吃吗?怕吃久了对肝功能有影响, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cfb791835, createdName=CHBLY, createdTime=Sat Jun 25 03:39:00 CST 2016, time=2016-06-25, status=1, ipAttribution=)]
    2016-09-13 舒心和人

    感谢分享,临床上很实用

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=132108, encodeId=0a27132108f7, content=文章很好,非常有益, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Sep 21 08:26:00 CST 2016, time=2016-09-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=125791, encodeId=1edf125e9183, content=感谢分享,临床上很实用, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160907/IMG57D00CF1965701770.jpg, createdBy=565c1948251, createdName=舒心和人, createdTime=Tue Sep 13 22:30:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=91412, encodeId=ca0b91412e8, content=期待后续报道, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuK9CDibOwszLoEBg36ZXqzB5NDasNV9GTfFDmBicM1V8hUS4OtTicG3IiaFIKq4wqD23LUxORRJXqjVs/0, createdBy=00e81647535, createdName=I come, createdTime=Tue Jun 28 08:23:00 CST 2016, time=2016-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=91337, encodeId=61f99133eb6, content=他丁类药物真的很重要, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=a37a1710612, createdName=oo902, createdTime=Mon Jun 27 16:24:00 CST 2016, time=2016-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=91068, encodeId=0c3791068a0, content=降脂的他丁药是跟降糖药一起终生吃吗?怕吃久了对肝功能有影响, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cfb791835, createdName=CHBLY, createdTime=Sat Jun 25 03:39:00 CST 2016, time=2016-06-25, status=1, ipAttribution=)]
    2016-06-28 I come

    期待后续报道

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=132108, encodeId=0a27132108f7, content=文章很好,非常有益, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Sep 21 08:26:00 CST 2016, time=2016-09-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=125791, encodeId=1edf125e9183, content=感谢分享,临床上很实用, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160907/IMG57D00CF1965701770.jpg, createdBy=565c1948251, createdName=舒心和人, createdTime=Tue Sep 13 22:30:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=91412, encodeId=ca0b91412e8, content=期待后续报道, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuK9CDibOwszLoEBg36ZXqzB5NDasNV9GTfFDmBicM1V8hUS4OtTicG3IiaFIKq4wqD23LUxORRJXqjVs/0, createdBy=00e81647535, createdName=I come, createdTime=Tue Jun 28 08:23:00 CST 2016, time=2016-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=91337, encodeId=61f99133eb6, content=他丁类药物真的很重要, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=a37a1710612, createdName=oo902, createdTime=Mon Jun 27 16:24:00 CST 2016, time=2016-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=91068, encodeId=0c3791068a0, content=降脂的他丁药是跟降糖药一起终生吃吗?怕吃久了对肝功能有影响, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cfb791835, createdName=CHBLY, createdTime=Sat Jun 25 03:39:00 CST 2016, time=2016-06-25, status=1, ipAttribution=)]
    2016-06-27 oo902

    他丁类药物真的很重要

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=132108, encodeId=0a27132108f7, content=文章很好,非常有益, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Sep 21 08:26:00 CST 2016, time=2016-09-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=125791, encodeId=1edf125e9183, content=感谢分享,临床上很实用, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160907/IMG57D00CF1965701770.jpg, createdBy=565c1948251, createdName=舒心和人, createdTime=Tue Sep 13 22:30:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=91412, encodeId=ca0b91412e8, content=期待后续报道, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuK9CDibOwszLoEBg36ZXqzB5NDasNV9GTfFDmBicM1V8hUS4OtTicG3IiaFIKq4wqD23LUxORRJXqjVs/0, createdBy=00e81647535, createdName=I come, createdTime=Tue Jun 28 08:23:00 CST 2016, time=2016-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=91337, encodeId=61f99133eb6, content=他丁类药物真的很重要, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=a37a1710612, createdName=oo902, createdTime=Mon Jun 27 16:24:00 CST 2016, time=2016-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=91068, encodeId=0c3791068a0, content=降脂的他丁药是跟降糖药一起终生吃吗?怕吃久了对肝功能有影响, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cfb791835, createdName=CHBLY, createdTime=Sat Jun 25 03:39:00 CST 2016, time=2016-06-25, status=1, ipAttribution=)]
    2016-06-25 CHBLY

    降脂的他丁药是跟降糖药一起终生吃吗?怕吃久了对肝功能有影响

    0

相关资讯

2016 ADA:猪胰岛移植可能成为糖尿病治疗新方向

第76届美国糖尿病协会科学年会上,美国匹兹堡大学医学院外科教授David K.C. Cooper博士带来了他们的研究成果:人-猪异种器官移植可能是人胰岛细胞移植的可行替代选择。

PNAS:心血管药物帮助治疗糖尿病并发症

贝尔法斯特皇后大学和伦敦大学学院的研究人员发现一种最初开发治疗心血管疾病的药物有可能降低糖尿病引起的并发症-失明。 根据世卫组织最近估计,全球约有4.22亿人患有糖尿病。这种疾病最常见的并发症之一就是视力丧失。糖尿病黄斑水肿发生在大约7%的糖尿病患者中,失明在西方世界是最常见的原因之一。在英国,糖尿病视网膜病变这个影响视觉的并发症与健康息息相关,相关的社会保健费用花费约1.16亿英镑。社会经济

ADA 2016:糖尿病高危患者可通过生活方式干预延迟或预防疾病发生

美国糖尿病协会科学年会称,对于糖尿病高危人群,生活方式干预可延迟或预防疾病的发生,并且这种影响是独立于减重的。匹兹堡大学公共卫生研究学院流行病学系教授Andrea M. Kriska博士同事对1796例参与者进行了12年的随访研究,随机分为生活方式干预组(营养及身体活动强化干预,以每周150分钟的运动时间和7%的体重下降为目标)(n = 589)、二甲双胍组(n = 599)或安慰剂组(n = 6

ADA 2016:自动化释放胰高血糖素可降低1型糖尿病患者的低血糖风险

美国糖尿病协会科学年会称,对于1型糖尿病患者,自动仿生胰腺释放的胰高血糖素相比安慰剂,有更少的症状性低血糖事件。马萨诸塞州总医院糖尿病研究中心的Courtney Balliro和同事对22名使用胰岛素泵或每日多次注射胰岛素的1型糖尿病患者进行了研究。参与者自己管理胰岛素,随机分配到自动化仿生胰腺释放胰高血糖素组或安慰剂组(每天随机)。主要研究结果是曲线下面积(AOC)和血糖低于60 mg/dL。数

控制糖尿病,减少卒中发生

糖尿病患者患卒中或心脏病的几率是非糖尿病人的两倍。并且与非糖尿病人相比,糖尿病患者发生卒中或心脏病时,年龄较轻。糖尿病是影响身体利用消化食物的能量的代谢紊乱型疾病。葡萄糖是我们身体的主要能量来源,我们所吃的大部分食物基本上都是分解成这种形式的糖。一旦消化,葡萄糖被分配在所有细胞中转化为能量。然而,葡萄糖只有在胰岛素的作用下才能进入细胞。胰腺产生胰岛素。当胰腺不能产生足够的胰岛素,或当细胞存在胰岛素

强化血糖控制降低糖尿病视网膜病变的风险

ACCORDION研究显示,2型糖尿病患者若控制血糖,则发生糖尿病性视网膜病变的风险减少一半。Emily Chew博士指出,这表明糖尿病患者控制血糖对其眼睛健康及视力有重要作用。 Chew和同事对1310名参与ACCORD研究(2003-2009)的民众进行了调查。参与者被随机分配到实验组和对照组(糖化血红蛋白目标值:<6%:7%、收缩压:<120mmhg:140mmhg、血脂:非诺贝

Baidu
map
Baidu
map
Baidu
map