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Int J Impot Res:阴茎勃起血流动力学分析的一种新方法

2020-10-29 AlexYang MedSci原创

通过阴茎彩色多普勒超声(PDUS)测量海绵体动脉的血流速度是评估勃起功能最常用的客观方法。然而,在一些临床病例中,这种方法需要通过有创腔内压(ICP)测量来增强,ICP可以说是更直接的勃起功能指标。

通过阴茎彩色多普勒超声(PDUS)测量海绵体动脉的血流速度是评估勃起功能最常用的客观方法。然而,在一些临床病例中,这种方法需要通过有创腔内压(ICP)测量来增强,ICP可以说是更直接的勃起功能指标。

最近,有研究人员开发了一个阴茎循环机制的集中参数模型(LPM),并集成到一个脉动的、特定于患者的双心室循环系统中,且以非侵入的方式估计ICP值。研究人员从4名随机勃起功能障碍患者获得了PDUS数据,并用于开发患者特异性LPMs。心输出量由体表面积估计,系统压力由血压计获得。通过优化确定的参数集,仅使用PDUS数据就能够预测患者特定的ICP值,并得到了帕帕林注射前和注射后的腔镜测量的验证。所开发的模型预测两个阶段的ICP的平均误差值为3mmHg。根据临床尺寸测量结果,勃起时预测的阴茎尺寸变化误差约为15%。

测量的PDUS和海绵体测量数据

最后,研究人员指出,所开发的数学模型有可能成为勃起功能评价中有效的无创工具,并能够大大扩展现有的临床决策参数。

原始出处:

Canberk Yildirim, Hakan Erturk, Kerem Pekkan et al. A novel method for hemodynamic analysis of penile erection. Int J Impot Res. Oct 2020

 

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    2021-08-23 habb
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    2020-10-31 dingxiaobo
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    2020-10-31 风铃826

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