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JACC:妊娠期高血压的发病率和远期预后研究

2020-05-09 MedSci原创 MedSci原创

妊娠期高血压(HDP)与后期心血管疾病风险增加相关,HDP的发病率通常使用不可靠的诊断评分进行评估;而且通常是在每次怀孕时表达的,这可能低估了生育后有HDP病史的妇女的数量。这项研究试图确定HDP在每

妊娠期高血压(HDP)与后期心血管疾病风险增加相关,HDP的发病率通常使用不可靠的诊断评分进行评估;而且通常是在每次怀孕时表达的,这可能低估了生育后有HDP病史的妇女的数量。这项研究试图确定HDP在每个妊娠期和每个妇女中的发表率,并确定其与未来慢性病和多发病率的关系,

本研究纳入分析了9862名孕妇,其中有7.3%患有HDP,3.3%患有子痫前期。如果根据每位孕妇进行评估,HDP和子痫前期的发病率均翻了一倍。有HDP病史的妇女在随后诊断中风(危险比[HR]:2.27;95%可信区间[CI]:1.37至3.76)、冠心病(HR:1.89;95%可信区间:1.26至2.82)、心律失常(HR:1.62;95%可信区间:1.28至2.05)、慢性肾脏病(HR:2.41;95%可信区间:1.54至3.78)和多发并发症(HR:1.25;95%置信区间:1.15至1.35)的风险会更高。

研究结果显示,根据每次妊娠情况的HDP人群发病率低估了生育期受这种疾病影响的妇女人数,HDP病史可明着增加未来慢性病和多发病的风险。

原始出处:

Vesna D et al.Incidence and Long-Term Outcomes of Hypertensive Disorders of Pregnancy.JACC.2020 May.

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    2021-04-04 hbwxf
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    2020-05-11 wjcjjian
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