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Sleep Breath:重度阻塞性睡眠呼吸暂停综合征与耳蜗功能损伤有关

2017-07-14 AlexYang MedSci原创

最近,有研究人员调查了具有中耳声传递的阻塞性睡眠呼吸暂停综合征(OSA)与耳蜗功能的关系。研究人员根据全睡眠多导图描记术规范和无副发病变对患有和不患有轻度、中等程度和重度OSA男性个体进行了研究。研究群体中的BMI不小于40kg/m2、现在或者过去OSA的治疗、患有心力衰竭、糖尿病、高血压、血脂异常、中风、慢性药物的使用和以前听力损伤历史风险的个体被排除。并对所有合格的参与者进行了完整的多导睡眠描

最近,有研究人员调查了具有中耳声传递的阻塞性睡眠呼吸暂停综合征(OSA)与耳蜗功能的关系。研究人员根据全睡眠多导图描记术规范和无副发病变对患有和不患有轻度、中等程度和重度OSA男性个体进行了研究。研究群体中的BMI不小于40kg/m2、现在或者过去OSA的治疗、患有心力衰竭、糖尿病高血压、血脂异常、中风、慢性药物的使用和以前听力损伤历史风险的个体被排除。并对所有合格的参与者进行了完整的多导睡眠描记术、通过能量吸收(EA)的宽带声导抗评估和畸变产物耳声发射(DPOAE)。

研究发现,所参与的总共有38名个体(age 35.8 ± 7.2 years, BMI 28.8 ± 3.8 kg/m2),并且分成了无OSA(n = 10, age 33.6 ± 6.4 years, BMI 26.9 ± 4.1 kg/m2)、轻度OSA(n = 11, age 32.8 ± 2.9 years, BMI 28.5 ± 3.5 kg/m2)、中等程度OSA(n = 8, age 34.1 ± 6.8 years, BMI 29.6 ± 3.3 kg/m2)和重度OSA(n = 9, age 41.2 ± 9.2 years, BMI 30.5 ± 3.8 kg/m2)4个小组。EA在不同的小组之间相似。与之不同,当与对照组、轻度、中等程度OSA组比较,患有重度OSA的病人表现出显著更低的DPOAE幅度(所有比较均为p ≤ 0.03)。

最后,研究人员指出,中耳声传递功能在患有OSA和不患有OSA成人中是相似的。另外,在没有明显副发病变的病人中,重度OSA与耳蜗功能损伤相关。

原始出处:

Matsumura E, Matas CG, Sanches SGG et al. Severe obstructive sleep apnea is associated with cochlear function impairment. Sleep Breath. July 2017.

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    2017-07-15 1e0ece0dm09(暂无匿称)

    谢谢

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