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Gastroenterology :内镜胃癌筛查可显著减少亚洲患者胃癌特异性死亡率

2018-05-07 zhangfan MedSci原创

研究发现,内镜胃癌筛查可显著减少亚洲患者胃癌特异性死亡率,但对于发病率无显著影响

目前内镜筛查胃癌发病率或死亡率的影响研究尚不充分,近日研究人员通过系统综述及荟萃分析考察了内镜筛查对胃癌发病和特异性死亡率的影响。

研究人员收集截止2018年3月8日,PubMed和EMBASE数据库中关于非胃癌患者接受内镜筛查的相关研究数据,包括队列和病例对照研究。参与者至少接受了1次内镜筛查,研究结论包含死亡率及胃癌发病率数据。

总计6个队列研究以及4个病例对照研究纳入本次荟萃分析,总计342013名参与者,全部来自亚洲地区。总体而言,内镜筛查可以降低40%的胃癌死亡风险(RR, 0.60; 95% CI, 0.49-0.73),但对于胃癌发病率无显著影响(RR, 1.14; 95% CI, 0.93-1.40)。亚组分析显示,相对于不接受筛查人群(RR, 0.58; 95% CI, 0.48-0.70)以及X射线筛查人群(RR, 0.33; 95% CI, 0.12-0.91),内镜筛查人群的胃癌死亡风险显著降低,但内镜筛查不能显著降低患者预期死亡风险(RR, 0.67; 95% CI, 0.38-1.16)。

研究发现,内镜胃癌筛查可显著减少亚洲患者胃癌特异性死亡率,但对于发病率无显著影响。

原始出处:


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  1. 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content=作者下结论较为保守.因为存在异质性.所以用的may,而且在发病率方面.作者连词用的[and"而不是[but".因为screening并不是胃癌危险因素的干预措施.所以screening和发病率是否降低.不存在必然联系.如果用but的话.会让读者以为[发病率没降低".是件坏事情.希望有所帮助, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=09642175596, createdName=1205fe67m58(暂无昵称), createdTime=Sun May 13 21:00:36 CST 2018, time=2018-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313992, encodeId=314d313992cf, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Fri May 11 05:50:10 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313682, encodeId=776f313682c6, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Thu May 10 05:52:25 CST 2018, time=2018-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313379, encodeId=94ed3133e9d8, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Wed May 09 06:37:08 CST 2018, time=2018-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313327, encodeId=d6fc31332eec, content=学习了, beContent=null, objectType=article, channel=null, 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    2018-07-24 许安
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content=作者下结论较为保守.因为存在异质性.所以用的may,而且在发病率方面.作者连词用的[and"而不是[but".因为screening并不是胃癌危险因素的干预措施.所以screening和发病率是否降低.不存在必然联系.如果用but的话.会让读者以为[发病率没降低".是件坏事情.希望有所帮助, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=09642175596, createdName=1205fe67m58(暂无昵称), createdTime=Sun May 13 21:00:36 CST 2018, time=2018-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313992, encodeId=314d313992cf, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Fri May 11 05:50:10 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313682, encodeId=776f313682c6, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Thu May 10 05:52:25 CST 2018, time=2018-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313379, encodeId=94ed3133e9d8, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Wed May 09 06:37:08 CST 2018, time=2018-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313327, encodeId=d6fc31332eec, content=学习了, beContent=null, objectType=article, channel=null, 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  5. 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content=作者下结论较为保守.因为存在异质性.所以用的may,而且在发病率方面.作者连词用的[and"而不是[but".因为screening并不是胃癌危险因素的干预措施.所以screening和发病率是否降低.不存在必然联系.如果用but的话.会让读者以为[发病率没降低".是件坏事情.希望有所帮助, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=09642175596, createdName=1205fe67m58(暂无昵称), createdTime=Sun May 13 21:00:36 CST 2018, time=2018-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313992, encodeId=314d313992cf, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Fri May 11 05:50:10 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313682, 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  6. 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level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f22260741, createdName=121832a9m88暂无昵称, createdTime=Wed May 09 05:45:35 CST 2018, time=2018-05-09, status=1, ipAttribution=)]
    2018-05-13 1205fe67m58(暂无昵称)

    作者下结论较为保守.因为存在异质性.所以用的may,而且在发病率方面.作者连词用的[and"而不是[but".因为screening并不是胃癌危险因素的干预措施.所以screening和发病率是否降低.不存在必然联系.如果用but的话.会让读者以为[发病率没降低".是件坏事情.希望有所帮助

    0

  7. 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content=作者下结论较为保守.因为存在异质性.所以用的may,而且在发病率方面.作者连词用的[and"而不是[but".因为screening并不是胃癌危险因素的干预措施.所以screening和发病率是否降低.不存在必然联系.如果用but的话.会让读者以为[发病率没降低".是件坏事情.希望有所帮助, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=09642175596, createdName=1205fe67m58(暂无昵称), createdTime=Sun May 13 21:00:36 CST 2018, time=2018-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313992, encodeId=314d313992cf, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Fri May 11 05:50:10 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313682, encodeId=776f313682c6, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Thu May 10 05:52:25 CST 2018, time=2018-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313379, encodeId=94ed3133e9d8, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Wed May 09 06:37:08 CST 2018, time=2018-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313327, encodeId=d6fc31332eec, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f22260741, createdName=121832a9m88暂无昵称, createdTime=Wed May 09 05:45:35 CST 2018, time=2018-05-09, status=1, ipAttribution=)]
    2018-05-11 1209e435m98(暂无昵称)

    学习了.谢谢分享

    0

  8. 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encryptionId=94ffe853a7, topicName=Gastroenterol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Fri Apr 12 04:21:00 CST 2019, time=2019-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1711472, encodeId=77d71e1147216, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Wed Feb 06 23:21:00 CST 2019, time=2019-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=314790, encodeId=a91f314e905d, content=作者下结论较为保守.因为存在异质性.所以用的may,而且在发病率方面.作者连词用的[and"而不是[but".因为screening并不是胃癌危险因素的干预措施.所以screening和发病率是否降低.不存在必然联系.如果用but的话.会让读者以为[发病率没降低".是件坏事情.希望有所帮助, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=09642175596, createdName=1205fe67m58(暂无昵称), createdTime=Sun May 13 21:00:36 CST 2018, time=2018-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313992, encodeId=314d313992cf, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Fri May 11 05:50:10 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313682, encodeId=776f313682c6, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Thu May 10 05:52:25 CST 2018, time=2018-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313379, encodeId=94ed3133e9d8, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Wed May 09 06:37:08 CST 2018, time=2018-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313327, encodeId=d6fc31332eec, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f22260741, createdName=121832a9m88暂无昵称, createdTime=Wed May 09 05:45:35 CST 2018, time=2018-05-09, status=1, ipAttribution=)]
    2018-05-10 秀红

    学习了

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=2072147, encodeId=d41620e21471e, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Tue Jul 24 22:21:00 CST 2018, time=2018-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1936562, encodeId=d8441936562c6, content=<a href='/topic/show?id=05948324216' target=_blank style='color:#2F92EE;'>#胃癌筛查#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83242, encryptionId=05948324216, topicName=胃癌筛查)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=33b92500139, createdName=12498b37m72暂无昵称, createdTime=Tue May 22 16:21:00 CST 2018, time=2018-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1899215, encodeId=c4851899215cf, content=<a href='/topic/show?id=6f746e94170' target=_blank style='color:#2F92EE;'>#特异性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67941, encryptionId=6f746e94170, topicName=特异性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc7a157, createdName=jinweidong, createdTime=Thu Sep 27 00:21:00 CST 2018, time=2018-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2064378, encodeId=184520643e8f8, content=<a href='/topic/show?id=94ffe853a7' target=_blank style='color:#2F92EE;'>#Gastroenterol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7853, encryptionId=94ffe853a7, topicName=Gastroenterol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Fri Apr 12 04:21:00 CST 2019, time=2019-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1711472, encodeId=77d71e1147216, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Wed Feb 06 23:21:00 CST 2019, time=2019-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=314790, encodeId=a91f314e905d, content=作者下结论较为保守.因为存在异质性.所以用的may,而且在发病率方面.作者连词用的[and"而不是[but".因为screening并不是胃癌危险因素的干预措施.所以screening和发病率是否降低.不存在必然联系.如果用but的话.会让读者以为[发病率没降低".是件坏事情.希望有所帮助, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=09642175596, createdName=1205fe67m58(暂无昵称), createdTime=Sun May 13 21:00:36 CST 2018, time=2018-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313992, encodeId=314d313992cf, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Fri May 11 05:50:10 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313682, encodeId=776f313682c6, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Thu May 10 05:52:25 CST 2018, time=2018-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313379, encodeId=94ed3133e9d8, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Wed May 09 06:37:08 CST 2018, time=2018-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313327, encodeId=d6fc31332eec, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f22260741, createdName=121832a9m88暂无昵称, createdTime=Wed May 09 05:45:35 CST 2018, time=2018-05-09, status=1, ipAttribution=)]
    2018-05-09 yfjms

    学习

    0

  10. 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content=作者下结论较为保守.因为存在异质性.所以用的may,而且在发病率方面.作者连词用的[and"而不是[but".因为screening并不是胃癌危险因素的干预措施.所以screening和发病率是否降低.不存在必然联系.如果用but的话.会让读者以为[发病率没降低".是件坏事情.希望有所帮助, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=09642175596, createdName=1205fe67m58(暂无昵称), createdTime=Sun May 13 21:00:36 CST 2018, time=2018-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313992, encodeId=314d313992cf, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Fri May 11 05:50:10 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313682, 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level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f22260741, createdName=121832a9m88暂无昵称, createdTime=Wed May 09 05:45:35 CST 2018, time=2018-05-09, status=1, ipAttribution=)]
    2018-05-09 121832a9m88暂无昵称

    学习了

    0

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