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Am J Cardiol:部分患者CABG术后没能按照指南推荐服药

2016-05-31 Mechront 译 MedSci原创

根据发表在美国心脏病学杂志数据,近一半的患者接受CABG后,没有采取必要的他汀类药物和阿司匹林治疗。美国心脏协会科学声明建议CABG后使用他汀类药物和阿司匹林作为二级预防长期使用。托马斯杰斐逊大学的Michael P. Savage博士和同事对381名接受诊断性心导管检查术的患者的数据进行了回顾性分析,患者平均年龄69岁,其中男性占78%。数据显示,导管检查时67%的患者服用他汀类药物,75%的患

根据发表在美国心脏病学杂志数据,近一半的患者接受CABG后,没有采取必要的他汀类药物和阿司匹林治疗。

美国心脏协会科学声明建议CABG后使用他汀类药物和阿司匹林作为二级预防长期使用。

托马斯杰斐逊大学的Michael P. Savage博士和同事对381名接受诊断性心导管检查术的患者的数据进行了回顾性分析,患者平均年龄69岁,其中男性占78%。

数据显示,导管检查时67%的患者服用他汀类药物,75%的患者服用阿司匹林,还有52%的患者两种药物均在服用。此外还有21%的患者服用阿司匹林加氯吡格雷;没有服用他汀药物与服药者相比,LDL ≥ 100mg/dl的比例分别为53%和26%(P < .001)。

明显的隐静脉移植在他汀治疗和没有使用他汀治疗的患者中分别有26%和25%(P = .867);整体移植在两组中分别有46%和43%(P = .517)。阿司匹林的使用并没有影响移植血管通畅或血管造影状态。服用阿司匹林的患者中,46%进行了移植,30%的病变和24%的闭塞,42%的移植隐静脉。

PCI或重复CABG血运重建在他汀组合非他汀组分别为62%和55%(P = .224);阿司匹林组和非阿司匹林组分别为62%和55%(P = .361)。

Savage说,“我们的研究证实了,患者在术后长期随访过程中,服用阿司匹林和他汀类药物明显不足。不管是患者还是医护人员,还需要努力。”

原始出处:

Curl K, et al. Frequency of Use of Statins and Aspirin in Patients With Previous Coronary Artery Bypass Grafting.Am J Cardiol. 2016; doi:10.1016/j.amjcard.2016.04.006.

Many patients skip recommended medications after CABG.Healio.May 31, 2016

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1781708, encodeId=5f4e1e817082d, content=<a href='/topic/show?id=5db8409ed8' target=_blank style='color:#2F92EE;'>#Cardiol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4097, encryptionId=5db8409ed8, topicName=Cardiol)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Wed Apr 05 20:39:00 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=88055, encodeId=1c8e88055b5, content=要多宣传, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=53751677671, createdName=沉心多思, createdTime=Wed Jun 01 15:37:00 CST 2016, time=2016-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87980, encodeId=e4ee8e980dd, content=了解一下!, beContent=null, objectType=article, channel=null, level=null, likeNumber=173, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Wed Jun 01 07:34:00 CST 2016, time=2016-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87952, encodeId=14378e9527e, content=值得研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=185, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Wed Jun 01 06:42:00 CST 2016, time=2016-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87951, encodeId=4f938e95164, content=的确这样, beContent=null, objectType=article, channel=null, level=null, likeNumber=184, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Wed Jun 01 06:41:00 CST 2016, time=2016-06-01, status=1, ipAttribution=)]
    2016-06-01 沉心多思

    要多宣传

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1781708, encodeId=5f4e1e817082d, content=<a href='/topic/show?id=5db8409ed8' target=_blank style='color:#2F92EE;'>#Cardiol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4097, encryptionId=5db8409ed8, topicName=Cardiol)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Wed Apr 05 20:39:00 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=88055, encodeId=1c8e88055b5, content=要多宣传, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=53751677671, createdName=沉心多思, createdTime=Wed Jun 01 15:37:00 CST 2016, time=2016-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87980, encodeId=e4ee8e980dd, content=了解一下!, beContent=null, objectType=article, channel=null, level=null, likeNumber=173, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Wed Jun 01 07:34:00 CST 2016, time=2016-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87952, encodeId=14378e9527e, content=值得研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=185, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Wed Jun 01 06:42:00 CST 2016, time=2016-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87951, encodeId=4f938e95164, content=的确这样, beContent=null, objectType=article, channel=null, level=null, likeNumber=184, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Wed Jun 01 06:41:00 CST 2016, time=2016-06-01, status=1, ipAttribution=)]
    2016-06-01 1dd8c52fm63(暂无匿称)

    了解一下!

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1781708, encodeId=5f4e1e817082d, content=<a href='/topic/show?id=5db8409ed8' target=_blank style='color:#2F92EE;'>#Cardiol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4097, encryptionId=5db8409ed8, topicName=Cardiol)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Wed Apr 05 20:39:00 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=88055, encodeId=1c8e88055b5, content=要多宣传, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=53751677671, createdName=沉心多思, createdTime=Wed Jun 01 15:37:00 CST 2016, time=2016-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87980, encodeId=e4ee8e980dd, content=了解一下!, beContent=null, objectType=article, channel=null, level=null, likeNumber=173, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Wed Jun 01 07:34:00 CST 2016, time=2016-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87952, encodeId=14378e9527e, content=值得研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=185, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Wed Jun 01 06:42:00 CST 2016, time=2016-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87951, encodeId=4f938e95164, content=的确这样, beContent=null, objectType=article, channel=null, level=null, likeNumber=184, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Wed Jun 01 06:41:00 CST 2016, time=2016-06-01, status=1, ipAttribution=)]
    2016-06-01 milkshark

    值得研究

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1781708, encodeId=5f4e1e817082d, content=<a href='/topic/show?id=5db8409ed8' target=_blank style='color:#2F92EE;'>#Cardiol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4097, encryptionId=5db8409ed8, topicName=Cardiol)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Wed Apr 05 20:39:00 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=88055, encodeId=1c8e88055b5, content=要多宣传, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=53751677671, createdName=沉心多思, createdTime=Wed Jun 01 15:37:00 CST 2016, time=2016-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87980, encodeId=e4ee8e980dd, content=了解一下!, beContent=null, objectType=article, channel=null, level=null, likeNumber=173, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Wed Jun 01 07:34:00 CST 2016, time=2016-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87952, encodeId=14378e9527e, content=值得研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=185, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Wed Jun 01 06:42:00 CST 2016, time=2016-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87951, encodeId=4f938e95164, content=的确这样, beContent=null, objectType=article, channel=null, level=null, likeNumber=184, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Wed Jun 01 06:41:00 CST 2016, time=2016-06-01, status=1, ipAttribution=)]
    2016-06-01 milkshark

    的确这样

    0

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