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未来同性恋夫妇或可通过IVG技术拥有真正属于自己的孩子

2015-12-19 Mechront 译 MedSci原创

乔治华盛顿大学探讨了利用体外配子发育(IVG)对人类生殖的可能性及其伦理和实际意义。老鼠IVG的配子来源于多能干细胞或胚胎干细胞,而对于人类该方法还没有允许用于生殖。Sonia Suter教授基于社会、科学、法律等分析了IVG的利弊,这对于IVG用于人类之前是必要的,她说:“何时与如何进行该试验是存在于伦理上的巨大挑战。”在以后有几种人可能使用IVG进行生殖:因身体原因不能怀孕、同性夫妇、绝经后女

乔治华盛顿大学探讨了利用体外配子发育(IVG)对人类生殖的可能性及其伦理和实际意义。老鼠IVG的配子来源于多能干细胞或胚胎干细胞,而对于人类该方法还没有被允许用于生殖。

Sonia Suter教授基于社会、科学、法律等分析了IVG的利弊,这对于IVG用于人类之前是必要的,她说:“何时与如何进行该试验是存在于伦理上的巨大挑战。”在以后有几种人可能使用IVG进行生殖:因身体原因不能怀孕、同性夫妇、绝经后女性、初潮前女性、超过2名儿童的父母亲。

目前同性夫妇必须依靠捐献者的配子以使用辅助生殖技术(ART)如人工受精或IVF等,以达到生殖目的。IVG与ART的最大区别就在于,IVG不会用到捐赠者的配子,后代是与同性夫妇均具有血缘关系的。例如使用个体细胞里的异性配子,再结合其他成员的自然配子,就可以产生一个胚胎了。

Suter教授说:“IVG在做产前检查时可以选出更健康或加强的后代,更容易也更健壮。会比当今出现更多的胚胎植入前胚胎遗传学诊断,大大改进选择胚胎的能力。”

未来对于IVG使用的最大关键问题或许是该过程的潜在风险。目前对该技术的认识十分有限,从分化好的细胞到未分化细胞以及擦除重置印记模式促进繁殖等方面的影响均是一片空白。唯一的证实技术有效性和安全性的办法,是在我们认为足够安全的条件下人类通过该技术诞下存活的后代。

原始出处:

 Sonia Suter, In Vitro gametogenesis: just another way to have a baby?.Journal of Law and the Biosciences,December 17, 2015

How in vitro gametogenesis could create the possibility of same-sex couples having children biologically related to both partners

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1350127, encodeId=3541135012e8b, content=<a href='/topic/show?id=81ea3894939' target=_blank style='color:#2F92EE;'>#同性恋#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38949, encryptionId=81ea3894939, topicName=同性恋)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Mon Dec 21 02:27:00 CST 2015, time=2015-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=46891, encodeId=5db84689161, content=怎么做到有双方的基因???, beContent=null, objectType=article, channel=null, level=null, likeNumber=169, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=df9e1651052, createdName=三三五五, createdTime=Sun Dec 20 20:02:00 CST 2015, time=2015-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=46796, encodeId=959a46e963a, content=伦理道德很难突破, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec6488436, createdName=a191008346, createdTime=Sun Dec 20 08:58:00 CST 2015, time=2015-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=46788, encodeId=ab2946e883e, content=科学会破坏伦理, beContent=null, objectType=article, channel=null, level=null, likeNumber=162, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96871613250, createdName=medcardio, createdTime=Sun Dec 20 08:31:00 CST 2015, time=2015-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=46762, encodeId=744046e62ba, content=是否与伦理认证, beContent=null, objectType=article, channel=null, level=null, likeNumber=131, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Sat Dec 19 21:07:00 CST 2015, time=2015-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=46738, encodeId=f72946e38bf, content=伦理, beContent=null, objectType=article, channel=null, level=null, likeNumber=185, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Sat Dec 19 15:13:00 CST 2015, time=2015-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=46737, encodeId=6ccb46e37c7, content=挺有前途和未来的项目, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0dcd1622180, createdName=ZChWei, createdTime=Sat Dec 19 14:10:00 CST 2015, time=2015-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=46735, encodeId=6b5446e3500, content=孩子怎么面对他的“父母”?他的朋友?!, beContent=null, objectType=article, channel=null, level=null, likeNumber=202, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7ee51614674, createdName=240612799, createdTime=Sat Dec 19 13:45:00 CST 2015, time=2015-12-19, status=1, ipAttribution=)]
    2015-12-20 三三五五

    怎么做到有双方的基因???

    0

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    2015-12-20 a191008346

    伦理道德很难突破

    0

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    2015-12-20 medcardio

    科学会破坏伦理

    0

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    2015-12-19 dhzzm

    是否与伦理认证

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1350127, encodeId=3541135012e8b, content=<a href='/topic/show?id=81ea3894939' target=_blank style='color:#2F92EE;'>#同性恋#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38949, encryptionId=81ea3894939, topicName=同性恋)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Mon Dec 21 02:27:00 CST 2015, time=2015-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=46891, encodeId=5db84689161, content=怎么做到有双方的基因???, beContent=null, objectType=article, channel=null, level=null, likeNumber=169, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=df9e1651052, createdName=三三五五, createdTime=Sun Dec 20 20:02:00 CST 2015, time=2015-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=46796, encodeId=959a46e963a, content=伦理道德很难突破, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec6488436, createdName=a191008346, createdTime=Sun Dec 20 08:58:00 CST 2015, time=2015-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=46788, encodeId=ab2946e883e, content=科学会破坏伦理, beContent=null, objectType=article, channel=null, level=null, likeNumber=162, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96871613250, createdName=medcardio, createdTime=Sun Dec 20 08:31:00 CST 2015, time=2015-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=46762, encodeId=744046e62ba, content=是否与伦理认证, beContent=null, objectType=article, channel=null, level=null, likeNumber=131, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Sat Dec 19 21:07:00 CST 2015, time=2015-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=46738, encodeId=f72946e38bf, content=伦理, beContent=null, objectType=article, channel=null, level=null, likeNumber=185, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Sat Dec 19 15:13:00 CST 2015, time=2015-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=46737, encodeId=6ccb46e37c7, content=挺有前途和未来的项目, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0dcd1622180, createdName=ZChWei, createdTime=Sat Dec 19 14:10:00 CST 2015, time=2015-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=46735, encodeId=6b5446e3500, content=孩子怎么面对他的“父母”?他的朋友?!, beContent=null, objectType=article, channel=null, level=null, likeNumber=202, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7ee51614674, createdName=240612799, createdTime=Sat Dec 19 13:45:00 CST 2015, time=2015-12-19, status=1, ipAttribution=)]
    2015-12-19 Wei Junhui

    伦理

    0

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    2015-12-19 ZChWei

    挺有前途和未来的项目

    0

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    2015-12-19 240612799

    孩子怎么面对他的“父母”?他的朋友?!

    0

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