Obstet Gynecol：肝硬化孕妇的临床和产科并发症！

2017-05-21 xing.T MedSci原创

与早期研究相比，尽管孕妇和胎儿死亡率较低，但肝硬化妇女的妊娠仍然与产科不良结局的高风险相关。

近日，妇产科权威杂志Obstetrics and Gynecology上发表了一研究文章，研究人员旨在评估肝硬化孕妇的临床特征和产科结局。

这是一项于2005年1月至2016年1月期间在大学医院的肝硬化妇女中进行的回顾性匹配队列研究。病例组中的妇女按照分娩年份、年龄、体重指数和胎次以1：4的比例匹配相应的对照组妇女。研究人员通过进行双变量和多变量分析来比较主要复合结局的患病率，其中包括以下任何一项：胎儿或新生儿死亡、胎盘早剥、先兆子痫、妊娠少于37周的早产和小于孕龄儿的新生儿。

在研究期间，分娩量约为110000例。其中33例患者被确诊为肝硬化，得到肝硬化发生率为每3333例妊娠（95％可信区间（CI）为3313-3353]中有1例。这三十三名妇女中有三十一人符合所有的入选标准。肝硬化最常见的病因是酒精性肝病。肝硬化患者的主要结局发生率为61％，对照组为12％。没有产妇死亡病例，活产出生率为97％。患有肝硬化的妇女更可能是非西班牙裔黑人，患有慢性高血压，并使用酒精。通过多变量Logistic回归表明肝硬化女性妊娠与复合结局相关（调整后的比值比为9.4，95％CI为 3.4-26.2）。

与早期研究相比，尽管孕妇和胎儿死亡率较低，但肝硬化妇女的妊娠仍然与产科不良结局的高风险相关。

原始出处：

Palatnik, Anna, et al. Medical and Obstetric Complications Among Pregnant Women With Liver Cirrhosis.Obstetrics & Gynecology.2017. http://journals.lww.com/greenjournal/Abstract/publishahead/Medical_and_Obstetric_Complications_Among_Pregnant.98415.aspx

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2017-09-18 yhy100200

#TET#

52 0
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2018-04-16 智者为医08

#NEC#

60 0
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2017-09-20 丁鹏鹏

#并发#

61 0
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2017-05-23 155无悔

学习了新的东西，谢谢了

107 0
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2017-05-22 135****7952平儿

学习了。。。。。。。。

112 0
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2017-05-22 tanxingdoctor

学习啦谢谢分享

98 0
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2017-05-22 jaysppr

感谢分享！

88 0
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2017-05-21 虈亣靌

感谢分享一下！！

90 0
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2017-05-21 tanxingdoctor

学习啦谢谢分享

47 0

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