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ACS 251:阿尔茨海默症老人食用蓝莓可改善认知功能

2016-03-14 MedSci MedSci原创

俄亥俄州辛辛那提大学的Robert Krikorian博士等研究人员将研究结果在第251届美国化学学会(ACS)上指出。 他们指出,这一发现证实了既往的动物研究和初步的人体试验,说明蓝莓有助于改善老人的记忆和认知功能。蓝莓的颜色是由于花青素所致,其他水果和蔬菜都有类似的颜色,如红莓、红叶卷心菜和茄子等。既往研究指出花青素可预防心血管疾病、神经退行性疾病和某些癌症。 阿尔茨海默氏症协会指出,在201

俄亥俄州辛辛那提大学的Robert Krikorian博士等研究人员将研究结果在第251届美国化学学会(ACS)上指出。 


他们指出,这一发现证实了既往的动物研究和初步的人体试验,说明蓝莓有助于改善老人的记忆和认知功能。

蓝莓的颜色是由于花青素所致,其他水果和蔬菜都有类似的颜色,如红莓、红叶卷心菜和茄子等。

既往研究指出花青素可预防心血管疾病、神经退行性疾病和某些癌症。 阿尔茨海默氏症协会指出,在2015年,约有530万美国人患阿尔茨海默症,其中约510万人年龄超过65岁。

随着美国年龄65岁以上老人的人口比例的增加,患老年痴呆症的人数也将增加。阿尔茨海默病协会预计,到2025年,这个年龄段的患病人数将增加40%,预计达710万人。

Krikorian和同事进行既往的临床试验表明,蓝莓对阿尔茨海默症的发病症状有一定的改观,所以他们进行了2个后续研究。

第1项研究中,研究人员招募47名68岁以上且患有轻度认知障碍的老人参与研究,他们每日接受一份冷冻蓝莓粉——相当于1份新鲜蓝莓(实验组)或安慰剂粉(对照组),每天1次,共16周。

Krikorian指出,相比对照组而言,实验组老人的认知能力和大脑功能明显改善。实验组老人记忆力及理解词汇和概念的能力得以提高,且通过fMRI显示实验组老人大脑活动增加。

在第2项研究中,94名年龄范围为62-80岁且自诉记忆力减退的老人被分为4组,他们分别服用蓝莓粉、鱼油、鱼油和蓝莓粉或安慰剂。

结果表明,服用鱼油或蓝莓粉的老人认知能力提高,但记忆力无明显提高,其对参与者进行fMRI显示效果不如第1项研究明显。Krikorian指出,这一发现可能是由于第2项研究的参与者认知功能障碍并没有那么严重。

Krikorian认为,尽管蓝莓对无认知功能障碍或轻度记忆力减退的民众可能没有什么益处,但是它对认知功能减退或受损的民众惹眼或许很有效果。

研究人员旨在进行更进一步的研究,他们希望将年龄在50-65岁、肥胖、高血压或高胆固醇的民众也列入研究范围内。

原始出处:

Researchers suggest blueberries could be used to fight Alzheimer's,MNT,14,Mar,2016

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    2016-03-16 yaanren
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    2016-03-15 sillywu

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Baidu
map