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Inflamm Bowel Dis:肌肉减少症预测炎症性肠病的手术治疗概率

2017-06-13 许奕晗 MedSci原创

肌肉减少症与炎症性肠病(IBD)手术治疗概率、患者死亡率的上升有关,但是肌肉减少症对于IBD手术的影响还没有文献报道。最近,一份研究收集了美国国家外科医师学院IBD患者手术质量改善资料,并就患者围术期并发症进行了回顾性研究分析。首先采用Hounsfield单位平均值法对患者进行术前断层扫描计算。对于肌肉减少症的定义为:Hounsfield单位平均值低于最低的第25百分位数。患者并发症采用Cla

肌肉减少症与炎症性肠病IBD)手术治疗概率、患者死亡率的上升有关,但是肌肉减少症对于IBD手术的影响还没有文献报道。最近,一份研究收集了美国国家外科医师学院IBD患者手术质量改善资料,并就患者围术期并发症进行了回顾性研究分析。首先采用Hounsfield单位平均值法对患者进行术前断层扫描计算。对于肌肉减少症的定义为:Hounsfield单位平均值低于最低的第25百分位数。患者并发症采用Clavien-Dindo分类系统进行分级。

研究结果显示:共入选了178名患者,患有肌肉减少症的患者年龄更大(P=0.001),有更高的比例出现高血压病(OR=2.23)和糖尿病(OR=5.27)。在小于40岁的患者中,肌肉减少症可以作为患者出现并发症的一个独立预测因子,同时此类患者的BMI指数可能是升高的。

在此次研究中,患有肌肉减少症的患者年龄普遍偏大,40岁以下的患者,肌肉减少可以明显影响术后结局。对于肌肉减少症的评估可以用于改善术前管理,并预测IBD患者手术风险。

原始出处:
Pedersen,Mark.et al.Sarcopenia is a Predictor of Surgical Morbidity in Inflammatory Bowel Disease.Inflamm Bowel Dis.June 09,2017.

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    2017-09-02 yuandd
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    2017-07-11 lxg951
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target=_blank style='color:#2F92EE;'>#肌肉减少症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80977, encryptionId=e2f4809e7e9, topicName=肌肉减少症)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIOca9icPByKxo3ZRUrvuibf7tWt7EScQ1NEiaKy4NCUctSU2jDjOayLicDIaicwUxaQhJ1SZKdEevgjRg/132, createdBy=4f272500131, createdName=若水123, createdTime=Thu Jun 15 14:16:00 CST 2017, time=2017-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1454812, encodeId=2199145481239, content=<a href='/topic/show?id=ca5f12e51d4' target=_blank style='color:#2F92EE;'>#NFL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12751, encryptionId=ca5f12e51d4, topicName=NFL)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Thu Jun 15 14:16:00 CST 2017, time=2017-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1512671, encodeId=a8a615126e123, content=<a href='/topic/show?id=070d36311d' target=_blank style='color:#2F92EE;'>#bowel#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3631, encryptionId=070d36311d, topicName=bowel)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f5b610492692, createdName=ms2536978994064944, createdTime=Thu Jun 15 14:16:00 CST 2017, time=2017-06-15, status=1, ipAttribution=)]
    2017-06-16 xuyihan

    不错不错,受用了

    0

  6. 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createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Thu Jun 15 14:16:00 CST 2017, time=2017-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1512671, encodeId=a8a615126e123, content=<a href='/topic/show?id=070d36311d' target=_blank style='color:#2F92EE;'>#bowel#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3631, encryptionId=070d36311d, topicName=bowel)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f5b610492692, createdName=ms2536978994064944, createdTime=Thu Jun 15 14:16:00 CST 2017, time=2017-06-15, status=1, ipAttribution=)]
    2017-06-15 虈亣靌

    学习了,受益匪浅。

    0

  7. 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  8. 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  9. 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createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Thu Jun 15 14:16:00 CST 2017, time=2017-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1512671, encodeId=a8a615126e123, content=<a href='/topic/show?id=070d36311d' target=_blank style='color:#2F92EE;'>#bowel#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3631, encryptionId=070d36311d, topicName=bowel)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f5b610492692, createdName=ms2536978994064944, createdTime=Thu Jun 15 14:16:00 CST 2017, time=2017-06-15, status=1, ipAttribution=)]
    2017-06-15 仁心济世
  10. 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