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BMC: 老年人减少肉食摄入可降低NAFLD的风险!

2021-05-24 MedSci原创 MedSci原创

非酒精性脂肪性肝病(NAFLD)是与代谢综合征最相关的肝病,全球的患病率在25%左右,正成为全球主要的健康和经济负担。

      非酒精性脂肪性肝病(NAFLD)是与代谢综合征最相关的肝病,全球的患病率在25%左右,正成为全球主要的健康和经济负担,此外,NAFLD不仅与肝脏疾病的不良结果相关,包括肝硬化和肝癌,而且还与非肝脏疾病的相关不良后果相关,如血管疾病和糖尿病有关。有研究显示,不健康的生活方式会导致NAFLD风险增加,肉类消费量的增加会导致饮食中胆固醇,饱和脂肪和其他有害化合物的摄入量增加,这些与NAFLD密切相关。本研究旨在评估中老年人中肉食与NAFLD风险和肝脏相关生化指标的相关性。

 

      研究人员对2015年4月至2017年8月在中国东南地区接受过身体检查的45岁以上的个体进行了回顾性研究。为了评估肉类摄入量与NAFLD风险之间的关联,研究人员采用logistic回归进行了相关性分析。用Spearman等级相关性检验了肉食与肝脏相关生化指标之间的关系。

 

      本项研究结果显示高摄入量的红肉(> 71.00 g /天)与NAFLD风险增加呈正相关关系,吸烟,饮茶,体育锻炼减少以及患有高血压,血脂异常和糖尿病都是影响NAFLD的发病的危险因素。暴露-反应关系分析表明,摄入红肉与NAFLD风险呈正相关,而且研究人员发现红肉摄入量与肝脏的生化指标如:血清γ-谷氨酰转移酶,丙氨酸转氨酶,天冬氨酸转氨酶,总甘油三酯和高密度脂蛋白胆固醇水平显着相关。

图:不同食物对于NAFLD的影响

      本项研究证实大量食用红肉与NAFLD风险呈正相关关系。此外,血清中与肝脏相关的生化指标水平与红肉摄入量显着相关,减少肉食可以降低NAFLD的风险!

 

 

原始出处:

Hewei Peng. Et al. Association of meat consumption with NAFLD risk and liver-related biochemical indexes in older Chinese: a cross-sectional study.BMC Gastroenterology.2021.

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    2022-03-14 lvygwyt2781
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    2021-05-24 ms6000001257867294

    受教了

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    2021-05-24 Blueblue7

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