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ARCH PATHOL LAB MED:肌红蛋白尿的尿液分析价值及应用

2019-12-02 MedSci MedSci原创

一般来说,尿肌红蛋白检测主要用于横纹肌溶解症患者肾脏损伤的诊断和风险评估。然而,由于缺乏快速和可靠的结果,其应用受到限制。

一般来说,尿肌红蛋白检测主要用于横纹肌溶解症患者肾脏损伤的诊断和风险评估。然而,由于缺乏快速和可靠的结果,其应用受到限制。肌红蛋白通过尿液试纸对血液产生积极反应,可作为肌红蛋白尿的指标。本研究的目的是在常规的临床实践中,通过尿液分析作为肌红蛋白尿的替代试验,评估血液和红细胞测量的性能和价值。

本研究是一项回顾性观察研究,包括通过尿液肌红蛋白检测患者尿液分析血红蛋白和红细胞结果。

研究结果显示,在截至201410月的15年期间,共对88个退伍军人事务设施的13 139例尿肌红蛋白结果进行了评估。在各实验室使用的方法中,定性尿肌红蛋白检测从2000年的53(47.1%)中的25例下降到2013年的77(6.4%)中的5例。在7311个测试中(55.6%)通过定量方法进行尿检同时进行,3915 53.5%)的血液跟踪结果为阴性,其中肌红蛋白为1000μg/ L或更高的170.4%)。 3+血液结果的187525.5%)的病例中,尿液中的血红蛋白≥1000μg/ L的有153例(33.8%)有血尿(≥5红细胞/微升)和109例的10931.9%)无血尿。

研究结果表明,尿液分析结果可靠地预测了肌红蛋白尿的缺失,可用于避免对尿肌红蛋白的过度检测,同时在无法立即获得尿肌红蛋白检测结果时提供有用的诊断信息。

原始出处:

Ron B. Schifman, MD; Daniel R. Luevano, BSHI, RHIAValue and Use of Urinalysis for Myoglobinuria

本文系梅斯医学(MedSci)原创编译整理,转载需授权!


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    2020-11-06 yb6560
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    2019-12-04 zhaohui6733
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