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Diabetic Med:2型糖尿病患者血糖控制与常见感染之间有无关联?

2017-07-06 MedSci MedSci原创

近日,国际杂志 《Diabetic medicine》上在线发表一项关于2型糖尿病患者血糖控制与常见感染之间的关联的一项队列研究,调查血糖控制对2型糖尿病患者感染发生率的影响。

近日,国际杂志 《Diabetic medicine》上在线发表一项关于2糖尿病患者血糖控制与常见感染之间的关联的一项队列研究,调查血糖控制对2糖尿病患者感染发生率的影响。

研究人员在英国的一个大型初级保健队列中(皇家全科医生研究与监测中心数据库),比较了20142糖尿病患者和无糖尿病患者的感染率。研究人员进行了多级逻辑回归以研究2型糖尿病对感染发生的影响,及血糖控制对上呼吸道感染,支气管炎,流感样疾病,肺炎,肠道传染病,单纯疱疹,皮肤和软组织感染,尿路感染,以及生殖器和会阴感染的影响。2型糖尿病患者使用最新的HbA 1c浓度分级为良好[HbA1c <53 mmol / mol<7%)],中度[HbA1c 53-69 mmol / mol7-8.5%)]和差[HbA1c > 69 mmol / mol> 8.5%)] 血糖控制。利用一些重要的社会人口因素和患者并发症对感染发生率进行校正。

研究人员确定了34 2782型糖尿病患者和613 052名无糖尿病患者进行比较。2型糖尿病患者除单纯疱疹外,其它感染的发生率较高。血糖控制不佳与支气管炎,肺炎,皮肤和软组织感染,尿路感染,生殖器和会阴感染的发病率增加有关,但与上呼吸道感染,流感样疾病,肠道感染性疾病或单纯疱疹病毒无关。

研究表明,几乎所有分析的感染在2型糖尿病患者中均比较常见。在血糖控制较差的人群中,细菌,真菌或酵母菌来源的感染较为常见。

原始出处:

J. L. Hine, S. de Lusignan, D. Burleigh,et al. Association between glycaemic control and common infections in people with Type 2 diabetes: a cohort study.

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    2017-07-06 QFXL123456

    糖尿病患者易合并感染

    0

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