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Front Neurol Neurosci:脑出血发生的流行病学

2015-11-29 phylis 译 MedSci原创

脑出血(ICH)的总发病率为24.6/100000人/年,并死亡率较高。了解脑出血发生的危险因素,制定主要预防策略。本文提供了脑出血发病率及ICH相关的危险因素的更新。方法:研究者检索了MEDLINE数据库(1980年到2014年10间)进行系统评价,ICH的流行病学,从原始文献中寻找ICH发生的频率及发现ICH相关危险因素的。结果:在过去的30年间,ICH发生并未改变,这可能与ICH患者危险因素

背景:脑出血(ICH)的总发病率为24.6例/100000人·年,且死亡率较高。了解脑出血发生的危险因素,制定主要预防策略。本文提供了脑出血发病率及ICH相关的危险因素的更新。

方法:研究者检索了MEDLINE数据库(1980年到2014年10间)进行系统评价,ICH的流行病学,从原始文献中寻找ICH发生的频率及发现ICH相关危险因素的。

结果:在过去的30年间,ICH发生并未改变,这可能与ICH患者危险因素的改变相关。ICH更易发生在冬季、男性患者中。亚洲人比其他人群更易发生ICH。高血压及高龄,饮酒及载脂蛋白ε2或ε4等位基因的存在,BMI值,糖尿病与ICH的发生相关。ICH发生下降包括高胆固醇血症及水果和蔬菜饮食较高。

结论:ICH的发生并未得到改变,但是地区发病率因种族,性别,季节和地理位置不同而不同。高收入国家,改善血压的有益作用可能由抗血栓药物应用增加来抵消。新的可改变的危险因素包括饮酒,BMI,糖尿病及蔬菜水果的摄入,所有这一切都可以作为ICH发生的一级预防。

原文出处:

Poon MT, Bell SM, Al-Shahi Salman R.  Epidemiology of Intracerebral Haemorrhage.  Front Neurol Neurosci. 2015 Nov.


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    2016-11-13 yinhl1978
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    2015-12-01 lsndxfj
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    2015-12-01 xugumin
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    2015-11-30 午夜星河

    善待

    0

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    2015-11-30 lixh1719

    亚洲生活方式变化太快

    0

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    2015-11-30 老段

    有意义

    0

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