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JAMA SURGERY:孕期接受阑尾或胆囊切除术出现不良妊娠结局的危险因素及危险分层

2017-05-20 MedSci MedSci原创

怀孕期间接受非产科手术的概率大约为千分之二,其中最常见的是阑尾切除术及胆囊切除术。因此,寻找孕期接受阑尾或胆囊切除术后出现不良妊娠结局的危险因素对降低不良妊娠的发生率至关重要。

怀孕期间接受非产科手术的概率大约为千分之二,其中最常见的是阑尾切除术及胆囊切除术。因此,寻找孕期接受阑尾或胆囊切除术后出现不良妊娠结局的危险因素对降低不良妊娠的发生率至关重要。

JAMA SURGERY近期发表了一篇文章,研究孕期接受阑尾或胆囊切除术后出现不良妊娠结局的危险因素,并进行了分层。作者回顾性分析了2003年1月1日至2012年12月31日的病例,使用多变量分析寻找孕期接受阑尾或胆囊切除术后出现不良妊娠结局的危险因素,并针对这些危险因素建立了评分系统。研究共纳入19926例孕妇,其中953例出现了1018次不良妊娠结局。3中最常见的不良结局为早产(35.4%),未足月产(26.4%)以及流产(25.7%)。与不良妊娠结局关系密切的危险因素包括宫颈机能不全(OR=24.29),妊娠期早产(OR=18.34),阴道炎或外因阴道炎(OR=5.17),脓毒症(OR=3.39).根据有显着统计学意义的变量建立的评分系统将研究样本分为3组,预测的不良妊娠结局可能性分别为2.5%(≤4分),8.2%(5-8分)以及21.8%(≥9分)。

文章最后认为,孕期接受阑尾切除术或胆囊切除术的孕妇约5%会出现不良妊娠结局,主要危险因素包括宫颈机能不全,妊娠期早产,阴道炎或外因阴道炎以及脓毒症。

原始出处:
Adam Sach,Jean Guglielminotti,et al.Risk Factors and Risk Stratification for Adverse Obstetrical Outcomes After Appendectomy or Cholecystectomy During Pregnancy.JAMA SURGERY.May 2017 doi:10.1001/jamasurg.2016.5045

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content=<a href='/topic/show?id=8c9f4492370' target=_blank style='color:#2F92EE;'>#妊娠结局#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44923, encryptionId=8c9f4492370, topicName=妊娠结局)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1fa82500120, createdName=12498a1cm67暂无昵称, createdTime=Mon May 22 00:49:00 CST 2017, time=2017-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1429789, encodeId=147f1429e8958, content=<a href='/topic/show?id=140783434c7' target=_blank style='color:#2F92EE;'>#胆囊切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83434, encryptionId=140783434c7, topicName=胆囊切除术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d3f94230600, createdName=yangfl07, createdTime=Mon May 22 00:49:00 CST 2017, time=2017-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1469450, encodeId=076814694505f, content=<a href='/topic/show?id=850120501c5' target=_blank style='color:#2F92EE;'>#不良妊娠结局#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20501, encryptionId=850120501c5, topicName=不良妊娠结局)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fa987034131, createdName=cmsvly, createdTime=Mon May 22 00:49:00 CST 2017, time=2017-05-22, status=1, ipAttribution=)]
    2018-01-12 chg121
  5. 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  6. 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content=<a href='/topic/show?id=8c9f4492370' target=_blank style='color:#2F92EE;'>#妊娠结局#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44923, encryptionId=8c9f4492370, topicName=妊娠结局)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1fa82500120, createdName=12498a1cm67暂无昵称, createdTime=Mon May 22 00:49:00 CST 2017, time=2017-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1429789, encodeId=147f1429e8958, content=<a href='/topic/show?id=140783434c7' target=_blank style='color:#2F92EE;'>#胆囊切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83434, encryptionId=140783434c7, topicName=胆囊切除术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d3f94230600, createdName=yangfl07, createdTime=Mon May 22 00:49:00 CST 2017, time=2017-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1469450, encodeId=076814694505f, content=<a href='/topic/show?id=850120501c5' target=_blank style='color:#2F92EE;'>#不良妊娠结局#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20501, encryptionId=850120501c5, topicName=不良妊娠结局)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fa987034131, createdName=cmsvly, createdTime=Mon May 22 00:49:00 CST 2017, time=2017-05-22, status=1, ipAttribution=)]
    2017-06-03 樊银杰

    很好的文章,很亟待解决的问题

    0

  7. 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content=<a href='/topic/show?id=8c9f4492370' target=_blank style='color:#2F92EE;'>#妊娠结局#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44923, encryptionId=8c9f4492370, topicName=妊娠结局)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1fa82500120, createdName=12498a1cm67暂无昵称, createdTime=Mon May 22 00:49:00 CST 2017, time=2017-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1429789, encodeId=147f1429e8958, content=<a href='/topic/show?id=140783434c7' target=_blank style='color:#2F92EE;'>#胆囊切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83434, encryptionId=140783434c7, topicName=胆囊切除术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d3f94230600, createdName=yangfl07, createdTime=Mon May 22 00:49:00 CST 2017, time=2017-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1469450, encodeId=076814694505f, content=<a href='/topic/show?id=850120501c5' target=_blank style='color:#2F92EE;'>#不良妊娠结局#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20501, encryptionId=850120501c5, topicName=不良妊娠结局)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fa987034131, createdName=cmsvly, createdTime=Mon May 22 00:49:00 CST 2017, time=2017-05-22, status=1, ipAttribution=)]
    2017-05-22 changjiu

    学习了,谢谢分享。

    0

  8. 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