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Oral Dis:系统回顾和荟萃分析结果表明牙周炎与哮喘、COPD和肺炎相关

2020-09-27 MedSci原创 MedSci原创

本研究旨在进行系统回顾和荟萃分析以评估近期牙周炎与哮喘、慢性阻塞性肺疾病(COPD)和肺炎之间的关系,该研究结果已在线发表于Oral Dis。

本研究旨在进行系统回顾和荟萃分析以评估近期牙周炎与哮喘、慢性阻塞性肺疾病(COPD)和肺炎之间的关系,该研究结果已在线发表于Oral Dis。

使用MEDLINE/PubMed、EMBASE、Lilacs、Web of Science、Scopus和SciELO数据库,包括灰色文献(ProQuest)进行文献检索。此外,研究人员还搜索了所选文章的参考文献列表。具有不同流行病学设计、评估人类受试者牙周炎和呼吸道疾病之间关联的研究均符合纳入条件。三位独立审稿人提取了文章选择和数据。使用固定效应和随机效应荟萃分析计算关联测量值(Ods Ratio-OR)和95%置信区间(95% CI)。

 

结果,数据库检索共发现3234条记录,只有13项研究符合资格标准,10项研究为meta分析提供了数据。使用随机效应模型,发现牙周炎与哮喘:校正OR:3.54(95%CI:2.47-5.07),I2=0%;与COPD:校正OR:1.78(95%CI:1.04-3.05),I2=37.9%;与肺炎:校正后OR:3.21(95%CI:1.997-5.17),I2=0%相关。

综上所述,本系统性综述的主要结果验证了牙周炎与哮喘、COPD和肺炎之间的关联。

 

原始出处:

 

Isaac Suzart Gomes-FilhoSimone Seixas da Cruz, et al., Periodontitis and respiratory diseases: A systematic review with meta-analysis. Oral Dis. 2020 Mar;26(2):439-446. doi: 10.1111/odi.13228. 

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    2021-03-08 venlin
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    2021-03-12 小几洁
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    2020-10-11 子沐

    这个靠谱不阿

    0

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    2020-09-28 1205a032m39(暂无昵称)

    学习了!牙周炎与呼吸道疾病存在相关性

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