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APJCN:用机械通气的慢性阻塞性肺病患者测定的与预测的静息能量消耗之比较及临床应用分析

2013-12-04 佚名 亚太临床营养杂志

为了研究机械通气的慢性阻塞性肺病(COPD)患者的能量代谢特点,比较间接测热法测定与Harris-Benedict公式预测的静息能量消耗(REE)的差异。并以此为依据,分析低能量的营养支持是否能改善患者蛋白质营养状况。【原文下载】 纳入了33例(男20例,女13例)COPD患者,并测定其REE。比较测定的REE(REEm)和HB公式计算的REE(REEH-B)及其校正值之间的差异,同时还分析了R

为了研究机械通气的慢性阻塞性肺病(COPD)患者的能量代谢特点,比较间接测热法测定与Harris-Benedict公式预测的静息能量消耗(REE)的差异。并以此为依据,分析低能量的营养支持是否能改善患者蛋白质营养状况。【原文下载

纳入了33例(男20例,女13例)COPD患者,并测定其REE。比较测定的REE(REEm)和HB公式计算的REE(REEH-B)及其校正值之间的差异,同时还分析了REEm与APACHEⅡ评分之间的关系。33例患者被随机分成低能量组(REEm的50%-90%)和常规能量组(REEm的90%-130%),按照以上标准进行营养支持。比较营养支持前和支持后7天的白蛋白、前白蛋白、转铁蛋白、血红蛋白和淋巴细胞计数。REEH-B和用1.2校正的值均明显低于REEm(p < 0.01) ;REEm与APACHEⅡ评分之间存在正相关(p<0.05或p<0.01)。营养支持后,常规能量组的血红蛋白明显降低(p<0.05),两组患者的淋巴细胞计数,以及常规能量组的转铁蛋白和前白蛋白均明显升高(p<0.05或p<0.01)。

结果提示:1)机械通气的COPD患者的REE升高;2)间接测热法是确定REE的最好方法,在不能作间接测热法时,Harris-Benedict公式可用于计算患者的REE,但要参照APACHEⅡ评分予以校正;3)低能量的营养支持在改善机械通气COPD患者的蛋白质营养状况优于常规能量的营养支持。

原文出处

Rao ZY, Wu XT, Wang MY, Hu W.Comparison between measured and predicted resting energy expenditure in mechanically ventilated patients with COPD.Asia Pac J Clin Nutr. 2012【原文下载

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    2014-09-01 amy0559
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    2014-08-05 tomyang96
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