Baidu
map

Oral Oncol:不刷牙,小心头颈癌找上你

2015-05-03 sunshine 译 MedSci原创

头颈癌(HNC)是指发生在口腔、咽喉、鼻窦、喉部、头骨基部以及头部的恶性肿瘤,是世界上第六好发癌症,其治疗难度较大。因此,了解HNC发生的任何有关因素都很重要,吸烟和喝酒是已确定的危险因素,而且是HNC发生的主要病因。其他的危险因素包括遗传因素、人类乳头瘤病毒(HPV)感染、牙周病、牙齿丧失、口腔卫生较差、较差的牙齿状态等在HNC的发生中也有作用。牙菌


头颈癌(HNC)是指发生在口腔、咽喉、鼻窦、喉部、头骨基部以及头部的恶性肿瘤,是世界上第六好发癌症,其治疗难度较大。因此,了解HNC发生的任何有关因素都很重要,吸烟和喝酒是已确定的危险因素,而且是HNC发生的主要病因。其他的危险因素包括遗传因素、人类乳头瘤病毒(HPV)感染、牙周病、牙齿丧失、口腔卫生较差、较差的牙齿状态等在HNC的发生中也有作用。

牙菌斑是龋病、牙龈炎、牙周病、牙齿丧失、口腔卫生差的原因。因此,去除牙菌斑在预防这些疾病的发生上具有重要的作用。现有的证据表明,刷牙是清除牙菌斑的有效方法,预防口腔疾病或可减少HNC的发生。

已有流行病学研究聚焦在刷牙与HNC之间的关系,然而,刷牙是否会降低头颈癌发生的风险尚未清楚。有由于目前还未有综述或meta分析来为此重要的临床问题提供定量的证据,因此我们做了此meta分析以调查刷牙与HNC发生风险之间的关系。

我们在PubMed 与 Embase上检索了截至2014年1月13日相关的文献,以明确观察刷牙与HNC之间的关系。经过研究筛选和数据提取,使用 RevMan 5.2进行此meta分析。

研究共纳入了18例病例对照研究,包含了7068个病例和9990个对照组。meta分析显示,与刷牙频率最高相比,刷牙频率最低的患HNC的风险显著提高了2.08倍(比值比 = 2.08, 95% 的可信区间 = 1.65–2.62)。校正了吸烟和喝酒因素后,其结果仍保持一致。

该meta分析表明,刷牙的频率与头HNC发生的风险显著相关。有效的刷牙可能是预防HNC的潜在措施,因此,我们建议刷牙的频率为每天两次(早上和晚上)。

原始出处:

Zeng XT, Leng WD, Zhang C, Liu J, Cao SY, Huang W.Meta-analysis on the association between toothbrushing and head and neck cancer.Oral Oncol. 2015 May;51(5):446-51. doi: 10.1016/j.oraloncology.2015.02.095. Epub 2015 Mar 6.

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=125344, encodeId=594e125344be, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 14:27:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1864649, encodeId=9f14186464947, content=<a href='/topic/show?id=16ce133504e' target=_blank style='color:#2F92EE;'>#Oncol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13350, encryptionId=16ce133504e, topicName=Oncol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b63894, createdName=minlingfeng, createdTime=Thu May 28 14:40:00 CST 2015, time=2015-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020163, encodeId=7fb12020163c8, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Mon Feb 22 21:40:00 CST 2016, time=2016-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1295867, encodeId=4a44129586ee2, content=<a href='/topic/show?id=f30a4441598' target=_blank style='color:#2F92EE;'>#头颈癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44415, encryptionId=f30a4441598, topicName=头颈癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6c32257, createdName=DEXTER3139, createdTime=Tue May 05 07:40:00 CST 2015, time=2015-05-05, status=1, ipAttribution=)]
    2016-09-13 1e10c84am36(暂无匿称)

    好文章,还会关注

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=125344, encodeId=594e125344be, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 14:27:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1864649, encodeId=9f14186464947, content=<a href='/topic/show?id=16ce133504e' target=_blank style='color:#2F92EE;'>#Oncol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13350, encryptionId=16ce133504e, topicName=Oncol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b63894, createdName=minlingfeng, createdTime=Thu May 28 14:40:00 CST 2015, time=2015-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020163, encodeId=7fb12020163c8, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Mon Feb 22 21:40:00 CST 2016, time=2016-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1295867, encodeId=4a44129586ee2, content=<a href='/topic/show?id=f30a4441598' target=_blank style='color:#2F92EE;'>#头颈癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44415, encryptionId=f30a4441598, topicName=头颈癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6c32257, createdName=DEXTER3139, createdTime=Tue May 05 07:40:00 CST 2015, time=2015-05-05, status=1, ipAttribution=)]
    2015-05-28 minlingfeng
  3. [GetPortalCommentsPageByObjectIdResponse(id=125344, encodeId=594e125344be, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 14:27:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1864649, encodeId=9f14186464947, content=<a href='/topic/show?id=16ce133504e' target=_blank style='color:#2F92EE;'>#Oncol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13350, encryptionId=16ce133504e, topicName=Oncol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b63894, createdName=minlingfeng, createdTime=Thu May 28 14:40:00 CST 2015, time=2015-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020163, encodeId=7fb12020163c8, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Mon Feb 22 21:40:00 CST 2016, time=2016-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1295867, encodeId=4a44129586ee2, content=<a href='/topic/show?id=f30a4441598' target=_blank style='color:#2F92EE;'>#头颈癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44415, encryptionId=f30a4441598, topicName=头颈癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6c32257, createdName=DEXTER3139, createdTime=Tue May 05 07:40:00 CST 2015, time=2015-05-05, status=1, ipAttribution=)]
    2016-02-22 小几洁
  4. [GetPortalCommentsPageByObjectIdResponse(id=125344, encodeId=594e125344be, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 14:27:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1864649, encodeId=9f14186464947, content=<a href='/topic/show?id=16ce133504e' target=_blank style='color:#2F92EE;'>#Oncol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13350, encryptionId=16ce133504e, topicName=Oncol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b63894, createdName=minlingfeng, createdTime=Thu May 28 14:40:00 CST 2015, time=2015-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020163, encodeId=7fb12020163c8, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Mon Feb 22 21:40:00 CST 2016, time=2016-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1295867, encodeId=4a44129586ee2, content=<a href='/topic/show?id=f30a4441598' target=_blank style='color:#2F92EE;'>#头颈癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44415, encryptionId=f30a4441598, topicName=头颈癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6c32257, createdName=DEXTER3139, createdTime=Tue May 05 07:40:00 CST 2015, time=2015-05-05, status=1, ipAttribution=)]

相关资讯

刷牙不彻底会加大患癌症死亡风险?

       据英国《每日邮报》6月11日报道,美国科学家称,刷牙不彻底导致的牙菌斑、牙周炎问题可能加大患癌症死亡的风险。据报道,五分之一的癌症患者有口腔感染和发炎症状。一项研究更显示,严重的牙菌斑、口腔细菌问题会将患癌死亡的风险增加80%,可能减少13年寿命。       据报

BMJ:刷牙不当患癌风险提高80%

  《英国医学杂志》研究发现:口腔不干净可能导致短命,刷牙不当易导致牙菌斑或口腔病菌过多,进而使患癌早亡危险增加80%,寿命减少13年。   口腔不干净不仅会影响形象,还可能导致短命。口腔感染还会引发炎症,通过损伤的牙龈进进入血液,让心脏受损引发多种疾病。可按日本牙齿健康自测表检查自己的牙齿。   瑞典科学家自1985年开始对随机抽取的1390名斯德哥尔摩参试者进行了为期24年的跟踪研究。研究

Baidu
map
Baidu
map
Baidu
map