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Diabetes Care:年轻1型糖尿病患者终末期肾病累积发病率降低

2018-10-24 xing.T MedSci原创

由此可见,在瑞典1型糖尿病患者人群中发生ESRD的风险仍然很低,而且似乎也随着时间的推移而有所降低。

糖尿病肾病是1型糖尿病的严重并发症。最近的研究表明,终末期肾病(ESRD)的发病率已经下降或者ESRD的发病已经推迟。近日,糖尿病领域权威杂志Diabetes Care上发表了一篇研究文章,研究人员分析了瑞典ESRD的发病率和时间变化趋势。

在这项研究中,研究人员纳入了病程>14年且糖尿病发病年龄为0-34岁的1型糖尿病患者。研究人员使用了三个国家糖尿病登记中心:瑞典儿童糖尿病登记中心、瑞典糖尿病发病率研究和国家糖尿病登记中心。瑞典肾脏登记处是瑞典全国肾脏替代治疗登记处,用于确定发生发展为ESRD的患者。

研究人员发现瑞典ESRD的累积发病率在糖尿病患病时间持续长达38年之后仍然很低(5.6%)。与1977-1984和1985-1990的发病率相比,1991-2001年期间1型糖尿病患者发生ESRD的发生率较低,且与糖尿病病程无关。

由此可见,在瑞典1型糖尿病患者人群中发生ESRD的风险仍然很低,而且似乎也随着时间的推移而有所降低。

原始出处:

Cecilia Toppe,et al. Decreasing Cumulative Incidence of End-Stage Renal Disease in Young Patients With Type 1 Diabetes in Sweden: A 38-Year Prospective Nationwide Study.Diabetes Care.2018.https://doi.org/10.2337/dc18-1276

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  5. 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  6. 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  7. 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    2018-10-24 misszhang

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