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Diabetes Care:T2DM患者白天嗜睡或提示低血糖

2013-10-18 佚名 丁香园

睡眠障碍性呼吸和困倦导致代谢、认知和行为障碍。睡眠障碍性呼吸在2型糖尿病中是比较常见的,该疾病要求患者坚持复杂的饮食、行为和药物治疗方案。低血糖是治疗过程中一个重要的副反应,它能够导致生理和心理的伤害,同时使最佳的血糖控制难以达标。因此,为了研究睡眠障碍与低血糖风险的相关性,来自英国爱丁堡皇家医院糖尿病科的Inkster等进行了一项研究,表明白天困倦可能是一个新颖的

睡眠障碍性呼吸和困倦导致代谢、认知和行为障碍。睡眠障碍性呼吸在2型糖尿病中是比较常见的,该疾病要求患者坚持复杂的饮食、行为和药物治疗方案。低血糖是治疗过程中一个重要的副反应,它能够导致生理和心理的伤害,同时使最佳的血糖控制难以达标。因此,为了研究睡眠障碍与低血糖风险的相关性,来自英国爱丁堡皇家医院糖尿病科的Inkster等进行了一项研究,表明白天困倦可能是一个新颖的低血糖危险因子。研究结果在线发表于2013年10月2日的美国《糖尿病治疗》(Diabetes Care)杂志上。

该项研究共有898名2型糖尿病患者完成了调查问卷,用以评价睡眠障碍性呼吸、白天困倦和出现的严重低血糖。

结果显示,Epworth 睡眠评分较高的患者明显更容易罹患严重低血糖。在线性回归分析 (变量包括年龄、性别、糖尿病病程、HbA1c、BMI和治疗方法)中,Epworth 睡眠评分是一个显著的严重低血糖预测因子。

研究表明,白天困倦可能是一个新颖的低血糖危险因子。

原文检索:

Inkster B, Riha RL, Van Look L, Williamson R, McLachlan S, Frier BM, Strachan MW, Price JF, Reynolds RM.Association Between Excessive Daytime Sleepiness and Severe Hypoglycemia in People With Type 2 Diabetes: The Edinburgh Type 2 Diabetes Study.Diabetes Care. 2013 Oct 2.


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