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J Rheumatol:RA患者需要持续缓解才能改善身体机能

2016-06-30 Mechront 译 MedSci原创

根据最近的研究,维持持续缓解的类风湿性关节炎患者更有可能改善身体功能。瑞典隆德大学临床科学部的Jon Thorkell Einarsson博士和同事对2416名类风湿关节炎(RA)患者进行了研究,他们的DAS28小于2.6或简化疾病活动指数(SDAI)不超过3.3,接受抗肿瘤坏死因子治疗。研究人员比较了达到持续缓解期为6个月和非持续缓解状态患者的健康评估问卷(HAQ)分数。有1177例患者达到DA

根据最近的研究,维持持续缓解的类风湿性关节炎患者更有可能改善身体功能。

瑞典隆德大学临床科学部的Jon Thorkell Einarsson博士和同事对2416名类风湿关节炎(RA)患者进行了研究,他们的DAS28小于2.6或简化疾病活动指数(SDAI)不超过3.3,接受抗肿瘤坏死因子治疗。研究人员比较了达到持续缓解期为6个月和非持续缓解状态患者的健康评估问卷(HAQ)分数。

有1177例患者达到DAS28缓解,这些患者中,采用DAS28评分标准,持续缓解382例(15.8%);采用SDAI标准,持续缓解186例(7.7%);DAS28缓解组的HAQ评分在首个12个月得到改善。研究人员指出,较高比例的持续缓解患者身体功能恢复较完整,HAQ评分也持续改善。

“从我们目前的研究结果来看,偶尔达到缓解可能是不够的,只有持续的缓解才能提高身体机能。”Einarsson及其同事写道。

原始出处:

Einarsson JT, et al.Sustained Remission Improves Physical Function in Patients with Established Rheumatoid Arthritis, and Should Be a Treatment Goal: A Prospective Observational Cohort Study from Southern Sweden.J Rheumatol. 2016;doi:10.3899/jrheum.150995.

Physical function improved among RA patients with sustained remission.Healio.June 29, 2016

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1716476, encodeId=16561e16476c3, content=<a href='/topic/show?id=5c14932094d' target=_blank style='color:#2F92EE;'>#身体机能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93209, encryptionId=5c14932094d, topicName=身体机能)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c54332230971, createdName=hbwxf, createdTime=Sat Nov 05 11:58:00 CST 2016, time=2016-11-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=129407, encodeId=386c12940e32, content=不错哦,会学到很多,喜欢梅斯医学文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sat Sep 17 11:44:00 CST 2016, time=2016-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=126610, encodeId=6e2c12661026, content=赞一个!好文章拜读了,认真学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Wed Sep 14 13:23:00 CST 2016, time=2016-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=107377, encodeId=920610e37702, content=好文,值得学习,赞!, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Tue Aug 30 11:15:00 CST 2016, time=2016-08-30, status=1, ipAttribution=)]
    2016-09-17 1e10c84am36(暂无匿称)

    不错哦,会学到很多,喜欢梅斯医学文章

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  3. [GetPortalCommentsPageByObjectIdResponse(id=1716476, encodeId=16561e16476c3, content=<a href='/topic/show?id=5c14932094d' target=_blank style='color:#2F92EE;'>#身体机能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93209, encryptionId=5c14932094d, topicName=身体机能)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c54332230971, createdName=hbwxf, createdTime=Sat Nov 05 11:58:00 CST 2016, time=2016-11-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=129407, encodeId=386c12940e32, content=不错哦,会学到很多,喜欢梅斯医学文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sat Sep 17 11:44:00 CST 2016, time=2016-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=126610, encodeId=6e2c12661026, content=赞一个!好文章拜读了,认真学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Wed Sep 14 13:23:00 CST 2016, time=2016-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=107377, encodeId=920610e37702, content=好文,值得学习,赞!, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Tue Aug 30 11:15:00 CST 2016, time=2016-08-30, status=1, ipAttribution=)]
    2016-09-14 ylzr123

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  4. [GetPortalCommentsPageByObjectIdResponse(id=1716476, encodeId=16561e16476c3, content=<a href='/topic/show?id=5c14932094d' target=_blank style='color:#2F92EE;'>#身体机能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93209, encryptionId=5c14932094d, topicName=身体机能)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c54332230971, createdName=hbwxf, createdTime=Sat Nov 05 11:58:00 CST 2016, time=2016-11-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=129407, encodeId=386c12940e32, content=不错哦,会学到很多,喜欢梅斯医学文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sat Sep 17 11:44:00 CST 2016, time=2016-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=126610, encodeId=6e2c12661026, content=赞一个!好文章拜读了,认真学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Wed Sep 14 13:23:00 CST 2016, time=2016-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=107377, encodeId=920610e37702, content=好文,值得学习,赞!, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Tue Aug 30 11:15:00 CST 2016, time=2016-08-30, status=1, ipAttribution=)]
    2016-08-30 ylzr123

    好文,值得学习,赞!

    0

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