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JACC:腹型肥胖能明显增加心衰患者死亡率!

2017-11-29 MedSci MedSci原创

目前,尚缺乏探究腹型肥胖与心衰伴保留型射血分数(HFpEF)患者预后的相关研究。本研究的目的旨在探究腹型肥胖与HFpEF患者全因死亡率的关系。本研究的数据来自TOPCAT临床试验,主要终点事件为全因死亡率,腹型肥胖的定义标准为男性腰围≥102cm,女性腰围≥88cm。最终功能纳入了3310名HFpEF患者,其中腹型肥胖的为2413名,非腹型肥胖的为897名。平均随访时间为3.4 ± 1.7年,随访

目前,尚缺乏探究腹型肥胖与心衰伴保留型射血分数(HFpEF)患者预后的相关研究。本研究的目的旨在探究腹型肥胖与HFpEF患者全因死亡率的关系。

本研究的数据来自TOPCAT临床试验,主要终点事件为全因死亡率,腹型肥胖的定义标准为男性腰围≥102cm,女性腰围≥88cm。最终功能纳入了3310名HFpEF患者,其中腹型肥胖的为2413名,非腹型肥胖的为897名。平均随访时间为3.4 ± 1.7年,随访期间,有500名患者死亡。全因死亡率在腹型肥胖组和非腹型肥胖组中分别为46.1/1000人年和40.7/1000人年。多变量调整后,肥胖组患者的全因死亡率要明显高于对照组(HR: 1.52; 95% [CI]: 1.16 - 1.99; p = 0.002),心源性和非心源性死亡率在腹型肥胖组患者中同样要更高(HR: 1.50; 95% CI: 1.08 - 2.08; p = 0.01 ,HR: 1.58; 95% CI: 1.00 - 2.51; p = 0.04)。

本研究结果显示,腹型肥胖能明显增加心衰伴保留型射血分数患者的全因死亡率。

原始出处:

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    2018-04-30 hbwxf
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    2017-12-01 沙漠浪人

    腹型肥胖能明显增加心衰伴保留型射血分数患者的全因死亡率

    0

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    2017-12-01 nymo

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