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Diabetes Care: 传统危险因素无法解释糖尿病患者死亡超额风险

2012-08-21 高晓方 医学论坛网

  西班牙学者的一项研究表明,与非糖尿病个体相比,糖尿病患者的死亡超额风险无法通过死亡危险因素或心血管疾病及癌症加以解释。论文于2012年8月8日在线发表于《糖尿病护理》(Diabetes Care)杂志。   此项研究共纳入4008例60岁及以上的受试者,并对其进行为期8年的随访。在基线时采集糖尿病和死亡主要因素相关性资料。对死亡危险因素进行进展校正之后利用Cox回归进行分析。  

  西班牙学者的一项研究表明,与非糖尿病个体相比,糖尿病患者的死亡超额风险无法通过死亡危险因素或心血管疾病及癌症加以解释。论文于2012年8月8日在线发表于《糖尿病护理》(Diabetes Care)杂志。

  此项研究共纳入4008例60岁及以上的受试者,并对其进行为期8年的随访。在基线时采集糖尿病和死亡主要因素相关性资料。对死亡危险因素进行进展校正之后利用Cox回归进行分析。

  结果显示,受试人群中共有667例糖尿病患者,随访期间共有972例受试者死亡。对年龄、婚姻状况、教育程度、医学咨询和药物治疗等进行校正之后,与非糖尿病受试者相比糖尿病患者的死亡危险比(HR)在男性和女性中分别为1.40和1.70。对包括心血管疾病和癌症在内的所有危险因素进行校正之后,上述死亡HR仍分别为1.43和1.67。纳入生活方式和随访期间疾病发生对糖尿病和死亡的相关性影响甚微。

  链接:Enrique Regidor, MD, PHD1,2,Josep Franch, MD, PHD3,4Mateu Seguí, MD3,5,Rosario Serrano, MD3,6Fernando Rodríguez-Artalejo, MD, PHD2,7 and ara Artola, MD3,8 Traditional Risk Factors Alone Could Not Explain the Excess Mortality in Patients With Diabetes.Diabetes Care

  
    

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