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Lancet:H7N9死亡风险低于H5N1高于H1N1

2013-06-28 吕诺 新华网

中国科学家6月24日在线发表于《柳叶刀》上的研究论文称,H7N9禽流感患者死亡风险远低于人感染H5N1禽流感,但高于季节性流感和甲型H1N1流感。 具有100多年历史的世界著名医学期刊《柳叶刀》杂志,24日同时在线发表了两篇由中国疾控中心和香港大学科学家合作完成的最新研究论文。其中,《人感染A(H7N9)禽流感病毒临床严重性评估》一文提出,人感染H7N9禽流感住院患者死亡风险为36%,临床严重性

中国科学家6月24日在线发表于《柳叶刀》上的研究论文称,H7N9禽流感患者死亡风险远低于人感染H5N1禽流感,但高于季节性流感和甲型H1N1流感。

具有100多年历史的世界著名医学期刊《柳叶刀》杂志,24日同时在线发表了两篇由中国疾控中心和香港大学科学家合作完成的最新研究论文。其中,《人感染A(H7N9)禽流感病毒临床严重性评估》一文提出,人感染H7N9禽流感住院患者死亡风险为36%,临床严重性低于约60%病死率、70%住院死亡风险的H5N1禽流感。H7N9禽流感病毒存在一定的轻症感染和无症状感染。公众对H7N9禽流感无需过度恐慌。

另一篇题为《中国人感染禽流感病毒H7N9和H5N1的流行病学特征比较:基于人群实验室确诊病例的研究》的论文,全球首次报道了H7N9和H5N1两种禽流感病毒人间病例关键流行病学特征的异同点。

论文提出,在城市地区,H7N9和H5N1病例男性均明显多于女性。但在农村地区,H7N9病例男性是女性的1.6倍,而H5N1病例女性是男性的2倍;H7N9病例一半以上为60岁及以上的老年人,但H5N1病例以青壮年为主;H7N9和H5N1病毒的潜伏期相似,平均值分别为3.1和3.3天;H7N9住院病例的死亡风险远低于H5N1病例;城市和农村地区H7N9病例的平均密切接触者人数分别是21和18人,均显着低于H5N1病例的密切接触者平均人数(城市90人,农村63人);H7N9病例发病至实验室确诊的平均间隔时间比H5N1病例缩短了2.4天,但在医院治疗时间明显长于H5N1病例。

据初步统计,从H7N9禽流感病毒发现至今,中国科学家已在世界最具影响力的医学科学期刊发表多篇相关研究论文。其中,《新英格兰医学》3篇,《科学》1篇,《柳叶刀》5篇。

中国疾控中心主任王宇指出,此次H7N9疫情防控和相关科学研究,彰显了近年来中国重大传染病防控和救治能力的显着提升。


Comparative epidemiology of human infections with avian influenza A H7N9 and H5N1 viruses in China: a population-based study of laboratory-confirmed cases


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    2014-01-14 howi
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    2013-06-30 TZF0806
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