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J VIROL:研究揭示我国华中地区 H5N6 禽流感病毒发生和演化特征

2017-04-19 佚名 武汉病毒研究所

自 2013 年 H5N6 亚型禽流感病毒首次在中国出现以来,该病毒已造成一定的人员伤亡,对公共健康构成了潜在的威胁。为进一步了解人感染 H5N6 前环境病毒的演化特征,中国科学院武汉病毒研究所崔杰课题组开展了华中地区 H5N6 病毒的演化模式研究,并取得重要进展。相关研究成果已在线发表在病毒学权威杂志 Journal of Virology 上。



自 2013 年 H5N6 亚型禽流感病毒首次在中国出现以来,该病毒已造成一定的人员伤亡,对公共健康构成了潜在的威胁。为进一步了解人感染 H5N6 前环境病毒的演化特征,中国科学院武汉病毒研究所崔杰课题组开展了华中地区 H5N6 病毒的演化模式研究,并取得重要进展。相关研究成果已在线发表在病毒学权威杂志 Journal of Virology 上。

世界卫生组织于 2016 年 11 月报道了一例人在华中地区一活禽市场环境感染 H5N6 亚型禽流感病毒的病例。研究人员针对该地区 2014-2015 年活禽市场周围环境中 H5N6 病毒流行状况进行研究,建立了一系列病毒发生和演化的动态模型。分析发现,该地区在人感染 H5N6 之前,环境中病毒的动力学较复杂,出现了至少 6 种病毒重配现象,包括属于 2.3.2 旧分支的 HA 基因引起的重配,并且分化成至少 4 种独立演化的支系,在当地流行。

这些研究结果对人感染禽流感病毒的预警提供了独特见解。

武汉病毒所病毒生物信息学学科组杜英英为本文第一作者,崔杰为通讯作者。本研究受国家重点研发计划、中科院率先行动“百人计划”资助。

原始出处:

Du Y, Chen M, Yang J, et al. Molecular Evolution and Emergence of H5N6 Avian Influenza Virus in Central China[J]. Journal of virology, 2017.

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    2017-12-15 longerg
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    2017-06-30 Julie W

    世界卫生组织于 2016 年 11 月报道了一例人在华中地区一活禽市场环境感染 H5N6 亚型禽流感病毒的病例。

    0

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    2017-04-19 ylzr123

    不错的方式,努力学习,刻苦专研,不断总结出来新经验。

    0

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