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J Appl Oral Sci:牙周治疗对牙周炎和糖尿病患者的影响

2020-05-24 MedSci原创 MedSci原创

关于2型糖尿病(T2D)和牙周炎患者的牙周治疗对血糖控制和全身炎症的影响尚无定论。本研究旨在评估洁治和根面平整(SRP)对2型糖尿病(T2D)患者的代谢控制和全身炎症的影响。

关于2型糖尿病(T2D)和牙周炎患者的牙周治疗对血糖控制和全身炎症的影响尚无定论。本研究旨在评估洁治和根面平整(SRP)对2型糖尿病(T2D)患者的代谢控制和全身炎症的影响。

 

使用MEDLINE数据库通过PubMed和Cochrane对照试验中心注册进行文献检索,从最早的记录到2018年7月。只有随机临床试验(RCT)被认为符合评估牙周治疗对T2D患者代谢指标 [糖化血红蛋白(HbA1C)]和全身性炎症[C反应蛋白(CRP)]的影响。使用Cochrane协作风险评估工具对研究的质量进行了评估。使用随机效应模型对HbA1c和CRP进行荟萃分析。通过计算每个研究中各组之间均值差异(DM)的加权平均值来估算总体干预效果的大小。使用Q统计方法(x2和I²)评估异质性。显著性水平确定为p <0.05。

 

研究共纳入了包括9个RCT。结果显示,SRP可有效降低HbA1c [DM = 0.56(0.36-0.75);p <0.01]和CRP [DM = 1.89(1.70-2.08); p <0.01]。未检测到异质性(I2 = 0%,p> 0.05)。

 

综上所述,该研究结果表明,SRP对T2D患者的代谢控制和减轻全身炎症有一定的影响。

 

原始出处:

 

Mauricio BaezaAlicia Morales, et al., Effect of Periodontal Treatment in Patients With Periodontitis and Diabetes: Systematic Review and Meta-Analysis. J Appl Oral Sci. 2020 Jan 10;28:e20190248. doi: 10.1590/1678-7757-2019-0248. eCollection 2020.

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    2020-07-08 12543f43m99暂无昵称

    学习阅读

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    2021-02-26 小几洁
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    2020-05-25 misszhang

    谢谢MedSci提供最新的资讯

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