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J Urol:狗狗也可以“嗅”出前列腺癌啦

2015-04-20 佚名 生物谷

近日,刊登在国际杂志The Journal of Urology上的一项研究报告中,来自意大利的科学家通过研究表明,受过训练的狗可以通过尿液样本样本“嗅”出和前列腺癌相关的化学物质。文章中研究者对2只三岁大的德国牧羊犬进行训练,让其利用患者的尿液样本检测出前列腺癌特殊的挥发性有机化合物。牧羊犬的鉴别技能已经成功对900名男性的样本进行了检测,其中包括362名前列腺癌患者及540名健康个体;Meds

近日,刊登在国际杂志The Journal of Urology上的一项研究报告中,来自意大利的科学家通过研究表明,受过训练的狗可以通过尿液样本样本“嗅”出和前列腺癌相关的化学物质。

文章中研究者对2只三岁大的德国牧羊犬进行训练,让其利用患者的尿液样本检测出前列腺癌特殊的挥发性有机化合物。牧羊犬的鉴别技能已经成功对900名男性的样本进行了检测,其中包括362名前列腺癌患者及540名健康个体;Medscape网站报道了具体的检测过程,即训犬员带着狗绕着一系列盖着的碗走一圈(碗中含有参与者的尿液),随后在走第二圈的时候,如果狗嗅到了前列腺癌患者含有特殊气味的尿液,就会在相应的碗跟前停下。

研究者表示,受训练的狗在检测前列腺癌的敏感性和特异性上的诊断准确率可以达到97%,实际上对于1号狗而言其敏感性为100%,特异性为98.7%;对于2号狗而言敏感性为98.6%,特异性为97.6%;这两只狗都可以检测低风险和严重的恶性前列腺癌。研究者Gianluigi Taverna指出,受过训练的犬类嗅觉系统会准确检测出前列腺癌患者尿液中的挥发性有机物,而且具有较高的特异性和敏感性,未来我们还需要进行更深入的研究来调查这种利用犬类来鉴别前列腺癌的潜在预测价值。

Claire Guest教授表示,本文研究为我们后期有效检测前列腺癌提供了一种新的思路,后期我们利用这种受过训练的牧羊犬来进行更多类型癌症的检测,这对于即使有效开发新型的癌症靶向疗法将非常关键。

原始出处:

Gianluigi Taverna, Lorenzo Tidu, Fabio Grizzi, Valter Torri, Alberto Mandressi, Paolo Sardella, Giuseppe La Torre, Giampiero Cocciolone, Mauro Seveso, Guido Giusti, Rodolfo Hurle, Armando Santoro, Pierpaolo Graziotti.Olfactory System of Highly Trained Dogs Detects Prostate Cancer in Urine Samples.The Journal of Urology, April, 2015, 193(4), Pages 1382-1387. DOI:http://dx.doi.org/10.1016/j.juro.2014.09.099

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    2015-04-21 chonhae

    0

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    2015-04-21 chonhae

    0

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    2015-04-21 chonhae

    0

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    2015-04-21 chonhae

    0

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    2015-04-21 chonhae

    奇葩

    0

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    2015-04-20 cspcsp

    是不是

    0

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    2015-04-20 cspcsp

    好假

    0

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