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J Hazard Mater:氧化石墨烯促进左氧氟沙星和环丙沙星在饱和和不饱和多孔介质中的转运

2018-01-30 MedSci MedSci原创

在这项工作中,研究人员探究了氧化石墨烯(GO)对两种典型氟喹诺酮类药物-左氧氟沙星(LEV)和环丙沙星(CIP)在饱和及不饱和石英砂介质中的共转运的影响。吸附等温线表明,GO对LEV和CIP的吸附容量大于Langmuir最大吸附容量409mgg-1(CIP-GO),而两种FQs对两种吸附剂的吸附亲和力可以按照CIP-sand> LEV-sand> LEV-GO> CIP-GO的顺

在这项工作中,研究人员探究了氧化石墨烯(GO)对两种典型氟喹诺酮类药物-左氧氟沙星(LEV)和环丙沙星(CIP)在饱和及不饱和石英砂介质中的共转运的影响。

吸附等温线表明,GO对LEV和CIP的吸附容量大于Langmuir最大吸附容量409mgg-1(CIP-GO),而两种FQs对两种吸附剂的吸附亲和力可以按照CIP-sand> LEV-sand> LEV-GO> CIP-GO的顺序进行。由于其强大的流动性和吸附能力,GO促进了两种FQs在饱和及不饱和多孔介质中的流动性。

GO结合的LEV/CIP负责多孔介质中的LEV/CIP转运,随着初始GO浓度的增加,GO结合FQs的运输量增加。在不饱和条件下,水分对GO结合CIP的转运影响不大,然而,随着含水量的降低,GO束缚LEV的流动性降低,表明从GO向气-水界面转移吸附的LEV。

综上所述,该研究结果表明,GO吸附降低了两种FQs的抗菌能力,但对抑制大肠杆菌生长仍然有效。

原始出处:

Sun K, Dong S, et al., Graphene oxide-facilitated transport of levofloxacin and ciprofloxacin in saturated and unsaturated porous media. J Hazard Mater. 2018 Jan 20;348:92-99. doi: 10.1016/j.jhazmat.2018.01.032. 

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    2018-10-26 yzh409
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  7. [GetPortalCommentsPageByObjectIdResponse(id=1696305, encodeId=4a90169630516, content=<a href='/topic/show?id=0107934e0a5' target=_blank style='color:#2F92EE;'>#转运#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93470, encryptionId=0107934e0a5, topicName=转运)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=47c429881595, createdName=yzh409, createdTime=Fri Oct 26 14:08:00 CST 2018, time=2018-10-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1651541, encodeId=6f08165154116, content=<a href='/topic/show?id=6e78e32573c' target=_blank style='color:#2F92EE;'>#石墨烯#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73257, encryptionId=6e78e32573c, topicName=石墨烯)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8db924213398, createdName=yangjxjc, createdTime=Tue Aug 28 17:08:00 CST 2018, time=2018-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1714759, encodeId=a04b1e1475948, content=<a href='/topic/show?id=021230e312' target=_blank style='color:#2F92EE;'>#AZ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3073, encryptionId=021230e312, topicName=AZ)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9e5031899089, createdName=12498e5fm22(暂无昵称), createdTime=Wed Oct 24 22:08:00 CST 2018, time=2018-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706959, encodeId=cf391e0695935, content=<a href='/topic/show?id=d2773359191' target=_blank style='color:#2F92EE;'>#化石#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33591, encryptionId=d2773359191, topicName=化石)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f4d531331396, createdName=ms7899726347904398, createdTime=Sat Nov 24 06:08:00 CST 2018, time=2018-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1530098, encodeId=7bb61530098a7, content=<a href='/topic/show?id=7f7848124f5' target=_blank style='color:#2F92EE;'>#左氧氟沙星#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48124, encryptionId=7f7848124f5, topicName=左氧氟沙星)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=666412016730, createdName=cqlidoudou, createdTime=Thu Feb 01 03:08:00 CST 2018, time=2018-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1560356, encodeId=dc801560356e7, content=<a href='/topic/show?id=10296839318' target=_blank style='color:#2F92EE;'>#环丙沙星#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=68393, encryptionId=10296839318, topicName=环丙沙星)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c3d615121574, createdName=swallow, createdTime=Thu Feb 01 03:08:00 CST 2018, time=2018-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1566365, encodeId=9f3c1566365aa, content=<a href='/topic/show?id=10296839318' target=_blank style='color:#2F92EE;'>#环丙沙星#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=68393, encryptionId=10296839318, topicName=环丙沙星)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c3d615121574, createdName=swallow, createdTime=Thu Feb 01 03:08:00 CST 2018, time=2018-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=283527, encodeId=0e2728352e1a, content=好文章.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Tue Jan 30 14:29:33 CST 2018, time=2018-01-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=283514, encodeId=df7628351435, content=学习了新知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Tue Jan 30 13:10:29 CST 2018, time=2018-01-30, status=1, ipAttribution=)]
  8. [GetPortalCommentsPageByObjectIdResponse(id=1696305, encodeId=4a90169630516, content=<a href='/topic/show?id=0107934e0a5' target=_blank style='color:#2F92EE;'>#转运#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93470, encryptionId=0107934e0a5, topicName=转运)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=47c429881595, createdName=yzh409, createdTime=Fri Oct 26 14:08:00 CST 2018, time=2018-10-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1651541, encodeId=6f08165154116, content=<a href='/topic/show?id=6e78e32573c' target=_blank style='color:#2F92EE;'>#石墨烯#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73257, encryptionId=6e78e32573c, topicName=石墨烯)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8db924213398, createdName=yangjxjc, createdTime=Tue Aug 28 17:08:00 CST 2018, time=2018-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1714759, encodeId=a04b1e1475948, content=<a href='/topic/show?id=021230e312' target=_blank style='color:#2F92EE;'>#AZ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3073, encryptionId=021230e312, topicName=AZ)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9e5031899089, createdName=12498e5fm22(暂无昵称), createdTime=Wed Oct 24 22:08:00 CST 2018, time=2018-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706959, encodeId=cf391e0695935, content=<a href='/topic/show?id=d2773359191' target=_blank style='color:#2F92EE;'>#化石#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33591, encryptionId=d2773359191, topicName=化石)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f4d531331396, createdName=ms7899726347904398, createdTime=Sat Nov 24 06:08:00 CST 2018, time=2018-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1530098, encodeId=7bb61530098a7, content=<a href='/topic/show?id=7f7848124f5' target=_blank style='color:#2F92EE;'>#左氧氟沙星#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48124, encryptionId=7f7848124f5, topicName=左氧氟沙星)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=666412016730, createdName=cqlidoudou, createdTime=Thu Feb 01 03:08:00 CST 2018, time=2018-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1560356, encodeId=dc801560356e7, content=<a href='/topic/show?id=10296839318' target=_blank style='color:#2F92EE;'>#环丙沙星#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=68393, encryptionId=10296839318, topicName=环丙沙星)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c3d615121574, createdName=swallow, createdTime=Thu Feb 01 03:08:00 CST 2018, time=2018-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1566365, encodeId=9f3c1566365aa, content=<a href='/topic/show?id=10296839318' target=_blank style='color:#2F92EE;'>#环丙沙星#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=68393, encryptionId=10296839318, topicName=环丙沙星)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c3d615121574, createdName=swallow, createdTime=Thu Feb 01 03:08:00 CST 2018, time=2018-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=283527, encodeId=0e2728352e1a, content=好文章.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Tue Jan 30 14:29:33 CST 2018, time=2018-01-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=283514, encodeId=df7628351435, content=学习了新知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Tue Jan 30 13:10:29 CST 2018, time=2018-01-30, status=1, ipAttribution=)]
    2018-01-30 1e0f8808m18(暂无匿称)

    好文章.学习了

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1696305, encodeId=4a90169630516, content=<a href='/topic/show?id=0107934e0a5' target=_blank style='color:#2F92EE;'>#转运#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93470, encryptionId=0107934e0a5, topicName=转运)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=47c429881595, createdName=yzh409, createdTime=Fri Oct 26 14:08:00 CST 2018, time=2018-10-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1651541, encodeId=6f08165154116, content=<a href='/topic/show?id=6e78e32573c' target=_blank style='color:#2F92EE;'>#石墨烯#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73257, encryptionId=6e78e32573c, topicName=石墨烯)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8db924213398, createdName=yangjxjc, createdTime=Tue Aug 28 17:08:00 CST 2018, time=2018-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1714759, encodeId=a04b1e1475948, content=<a href='/topic/show?id=021230e312' target=_blank style='color:#2F92EE;'>#AZ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3073, encryptionId=021230e312, topicName=AZ)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9e5031899089, createdName=12498e5fm22(暂无昵称), createdTime=Wed Oct 24 22:08:00 CST 2018, time=2018-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706959, encodeId=cf391e0695935, content=<a href='/topic/show?id=d2773359191' target=_blank style='color:#2F92EE;'>#化石#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33591, encryptionId=d2773359191, topicName=化石)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f4d531331396, createdName=ms7899726347904398, createdTime=Sat Nov 24 06:08:00 CST 2018, time=2018-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1530098, encodeId=7bb61530098a7, content=<a href='/topic/show?id=7f7848124f5' target=_blank style='color:#2F92EE;'>#左氧氟沙星#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48124, encryptionId=7f7848124f5, topicName=左氧氟沙星)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=666412016730, createdName=cqlidoudou, createdTime=Thu Feb 01 03:08:00 CST 2018, time=2018-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1560356, encodeId=dc801560356e7, content=<a href='/topic/show?id=10296839318' target=_blank style='color:#2F92EE;'>#环丙沙星#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=68393, encryptionId=10296839318, topicName=环丙沙星)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c3d615121574, createdName=swallow, createdTime=Thu Feb 01 03:08:00 CST 2018, time=2018-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1566365, encodeId=9f3c1566365aa, content=<a href='/topic/show?id=10296839318' target=_blank style='color:#2F92EE;'>#环丙沙星#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=68393, encryptionId=10296839318, topicName=环丙沙星)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c3d615121574, createdName=swallow, createdTime=Thu Feb 01 03:08:00 CST 2018, time=2018-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=283527, encodeId=0e2728352e1a, content=好文章.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Tue Jan 30 14:29:33 CST 2018, time=2018-01-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=283514, encodeId=df7628351435, content=学习了新知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Tue Jan 30 13:10:29 CST 2018, time=2018-01-30, status=1, ipAttribution=)]
    2018-01-30 Y—xianghai

    学习了新知识

    0

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