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Diabet Med:产后较孕前体重改变对代谢综合征的影响

2015-05-21 MedSci MedSci原创

目前临床上有许多关于妊娠期糖尿病和代谢的研究,例如孕期体重增长情况对以后代谢的影响。但是关于体重改变的时间段绝大多数集中在妊娠期这个时期,而近期Li W等人则着眼于从妊娠期到产后这个跨度,对妊娠期糖尿病的中国女性进行了一项调查,探究孕前到产后1-5年体重的变化和代谢综合征的关系。而代谢综合征是指人体的蛋白质、脂肪、碳水化合物等物质发生代谢紊乱的病理状态,是一组复杂的代谢紊乱症候群,是导致糖尿病心脑

目前临床上有许多关于妊娠期糖尿病和代谢的研究,例如孕期体重增长情况对以后代谢的影响。但是关于体重改变的时间段绝大多数集中在妊娠期这个时期,而近期Li W等人则着眼于从妊娠期到产后这个跨度,对妊娠期糖尿病的中国女性进行了一项调查,探究孕前到产后1-5年体重的变化和代谢综合征的关系。而代谢综合征是指人体的蛋白质、脂肪、碳水化合物等物质发生代谢紊乱的病理状态,是一组复杂的代谢紊乱症候群,是导致糖尿病心脑血管疾病的危险因素。是一个很麻烦很让人讨厌的存在。

该项回顾性队列研究纳入了产后1-5年的1263名患妊娠期糖尿病的女性,研究者根据参与者从孕前到纳入研究时体重变化情况分为以下四组:减少≥ 3 kg、体重稳定(± 3 kg)、增加3-7 kg、增加≥7 kg。

研究结果显示,从孕前到产后1-5年体重变化情况不同的4个组代谢综合征的发生率分别为:减少≥ 3 kg,12.1%;体重稳定(± 3 kg),16.2%;增加3-7 kg,增加3-7 kg;增加≥7 kg,44.3%。体重改变和代谢综合征正相关的趋势在孕前体重正常(BMI < 24 kg/m2 )、超重(BMI 24-27.9 kg/m2 )和肥胖(BMI ≥ 28 kg/m2 )的女性群体均有发现。并且代谢综合征的发病率在以下机组群体中相似:孕前体重正常而体重改变增加≥7 kg、孕前超重而体重稳定(± 3 kg)、孕前肥胖但是产后体重减少≥ 3 kg (P = 0.62)。

研究结果表明,孕期有妊娠期糖尿病病史女性,如果产后较孕前体重增加过多,那么其代谢综合征风险会增高。妊娠期糖尿病孕妇一经诊断,需要对其进行体重的合理控制,尤其是孕前就超重或肥胖的群体。

原始出处:

Li W, Liu H, Qiao Y, et al. Metabolic syndrome of weight change from pre-pregnancy to 1-5 years post-partum among Chinese women with prior gestational diabetes. Diabet Med. 2015 .

本文系Medsci原创编译整理!转载需要先获得授权,并附原文链接。谢谢!


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    2016-04-17 仁医06
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    2015-06-09 ljjj1053

    认真学习了

    0

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    2015-05-27 ktorresjie

    妊娠期糖尿病孕妇一经诊断,产后应密切监控自己的体重

    0

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