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J Clin Neurol:胃部幽门螺杆菌感染和帕金森症有密切关联

2016-06-14 佚名 生物谷

研究人员报告称,常见细菌感染人类的胃与帕金森病的症状恶化有重大关联。 帕金森病是世界上第二种最常见的神经退行性疾病,会引起肢体震颤,减少运动的协调性。该病的原因仍然未知,医生目前只能治疗疾病的症状。 马来西亚大学的研究人员分析了一小群帕金森症患者,他们有的携带,有的未携带感染幽门螺杆菌的胃粘膜。他们的研究结果显示,约占总数三分之一的感染测试与帕金森病相关。 在机动性能测试中受病菌感染的患者

研究人员报告称,常见细菌感染人类的胃与帕金森病的症状恶化有重大关联。

帕金森病是世界上第二种最常见的神经退行性疾病,会引起肢体震颤,减少运动的协调性。该病的原因仍然未知,医生目前只能治疗疾病的症状。

马来西亚大学的研究人员分析了一小群帕金森症患者,他们有的携带,有的未携带感染幽门螺杆菌的胃粘膜。他们的研究结果显示,约占总数三分之一的感染测试与帕金森病相关。

在机动性能测试中受病菌感染的患者被治疗后会减少帕金森病症状。

超过一半的世界人口携带幽门螺杆菌,感染率最高的国家在亚洲。它会影响肠道粘膜发展,引起慢性感染,经常在儿童时期感染细菌。这种细菌可以导致一系列消化道疾病,该细菌可以无限繁殖除非经过治疗,虽然有些患者还没有显示出任何症状。

研究者提出了两个主要的理论来解释他们的结果。首先,感染可以减少左旋多巴的吸收,这种药物可以减少帕金森病的症状。经过进一步推测,慢性幽门螺杆菌感染可能加剧甚至引起帕金森病。然而,他们也推测,帕金森病也可能使患者更容易感染幽门螺杆菌。

研究人员说他们对103名受试者进行研究,目的主要是确认幽门螺杆菌感染和帕金森病之间的联系。

但是他们说他们发现幽门螺杆菌感染和帕金森病症状的恶化之间的联系非常紧密,由此可以设计临床试验来证实它,更深入的探讨其原因。

原始出处:

Çamcı G, Oğuz S. Association between Parkinson's Disease and Helicobacter Pylori. J Clin Neurol. 2016 Apr;12(2):147-50

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    2016-12-04 yinhl1978
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    2016-10-31 kcb069
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    2016-10-12 ylzr123

    学习了,好文值得点赞!

    0

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    2016-07-22 1dd8c52fm63(暂无匿称)

    研究中!

    0

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    2016-06-23 微分

    显著性差异

    0

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    2016-06-16 howi
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    2016-06-15 1ddb8c8bm83(暂无匿称)

    好奇这种相关的特异性体现在哪里

    0

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