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Arthritis Rheumatol:全球类风湿性关节炎作为死亡原因的变化趋势!

2017-05-29 xing.T MedSci原创

由此可见,归因于RA的死亡率在全球范围内有所下降。然而,RA死亡率上存在着很大的国家之间的差距,但随着时间的推移国家间差距有所减少。人口老龄化以及RA死亡率的下降可能会导致疾病的经济负担增加,这个问题在制订政策时应予以考虑。

近日,风湿免疫性疾病领域权威杂志Arthritis & Rheumatology上发表了一篇研究文章,研究人员旨在评估全球31个国家在1987年至2011年期间类风湿关节炎(RA)作为死亡的根本原因(UCD)的趋势。

研究人员从世界卫生组织和联合国的死亡率数据库来收集死亡率和人群数据。年龄标准化死亡率(ASMR)通过直接标准化的方式进行计算。研究人员应用连接点的回归分析来进行趋势分析,使用国家之间的差异和Gini系数来评估国家之间的差距。由于死亡人数偏低,研究人员采用三年的平均水平来调整ASMR。在1987年至2011年期间RA死亡人数的变化采用两个对抗事实的场景来进行分解。

研究人员发现以RA登记作为UCD的绝对死亡人数从1987年的9281人(占全因死亡人数的0.12%)到2011年的8428人(占全因死亡人数的0.09%)。平据ASMR从1987-89年的7.1人/百万人每年下降至2009-11年额3.7人/百万人每年(减少了48.2%)。在21个国家中可以观察到ASMR降低了至少有25%,另有3个国家被观察到了相应的增加。RA的死亡率持续下降,ASMR平均每年下降3%。国家之间的绝对和相对差距在研究期间也有所减少。

由此可见,归因于RA的死亡率在全球范围内有所下降。然而,RA死亡率上存在着很大的国家之间的差距,但随着时间的推移国家间差距有所减少。人口老龄化以及RA死亡率的下降可能会导致疾病的经济负担增加,这个问题在制订政策时应予以考虑。

原始出处:

Aliasghar A Kiadaliri, et al. Rheumatoid arthritis as underlying cause of death in 31 countries, 1987-2011: Trend analysis of WHO mortality database. Arthritis & Rheumatology.2017. http://onlinelibrary.wiley.com/doi/10.1002/art.40091/full

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    2017-06-11 189****7206

    学习了谢谢分享。

    0

  4. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=00501987275, createdName=130****4638, createdTime=Fri Jun 09 07:14:54 CST 2017, time=2017-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=207825, encodeId=349b20e82546, content=学习了谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=00501987275, createdName=130****4638, createdTime=Wed Jun 07 21:00:09 CST 2017, time=2017-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=205716, encodeId=2a25205e16cc, content=学习了,新知识。, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, 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05:19:00 CST 2017, time=2017-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1483431, encodeId=abf3148343115, content=<a href='/topic/show?id=55a6100826cc' target=_blank style='color:#2F92EE;'>#风湿性关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100826, encryptionId=55a6100826cc, topicName=风湿性关节炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c237911872, createdName=ms1467340776200723, createdTime=Wed May 31 05:19:00 CST 2017, time=2017-05-31, status=1, ipAttribution=)]
    2017-06-09 130****4638

    学习了谢谢分享。

    0

  5. 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05:19:00 CST 2017, time=2017-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1483431, encodeId=abf3148343115, content=<a href='/topic/show?id=55a6100826cc' target=_blank style='color:#2F92EE;'>#风湿性关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100826, encryptionId=55a6100826cc, topicName=风湿性关节炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c237911872, createdName=ms1467340776200723, createdTime=Wed May 31 05:19:00 CST 2017, time=2017-05-31, status=1, ipAttribution=)]
    2017-06-07 130****4638

    学习了谢谢分享。

    0

  6. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=d41c2055892, createdName=184****9840, createdTime=Thu Jun 01 00:54:08 CST 2017, time=2017-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1333859, encodeId=48ba133385988, content=<a href='/topic/show?id=5306e6164b6' target=_blank style='color:#2F92EE;'>#类风湿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76164, encryptionId=5306e6164b6, topicName=类风湿)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eq2AGzrugK9ZUjU3eJxzM901ophWib0xJDrSicy49ibWl3zB5pbDto7eoR6tnzwOiaKdbq1a8PcbYFFrw/132, createdBy=6ff22500098, createdName=ms4964546379600229, createdTime=Wed May 31 05:19:00 CST 2017, time=2017-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1483431, encodeId=abf3148343115, content=<a href='/topic/show?id=55a6100826cc' target=_blank style='color:#2F92EE;'>#风湿性关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100826, encryptionId=55a6100826cc, topicName=风湿性关节炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c237911872, createdName=ms1467340776200723, createdTime=Wed May 31 05:19:00 CST 2017, time=2017-05-31, status=1, ipAttribution=)]
    2017-06-02 Y—xianghai

    学习了,新知识。

    0

  7. 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05:19:00 CST 2017, time=2017-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1483431, encodeId=abf3148343115, content=<a href='/topic/show?id=55a6100826cc' target=_blank style='color:#2F92EE;'>#风湿性关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100826, encryptionId=55a6100826cc, topicName=风湿性关节炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c237911872, createdName=ms1467340776200723, createdTime=Wed May 31 05:19:00 CST 2017, time=2017-05-31, status=1, ipAttribution=)]
    2017-06-02 189****7206

    学习了谢谢分享。

    0

  8. 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05:19:00 CST 2017, time=2017-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1483431, encodeId=abf3148343115, content=<a href='/topic/show?id=55a6100826cc' target=_blank style='color:#2F92EE;'>#风湿性关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100826, encryptionId=55a6100826cc, topicName=风湿性关节炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c237911872, createdName=ms1467340776200723, createdTime=Wed May 31 05:19:00 CST 2017, time=2017-05-31, status=1, ipAttribution=)]
    2017-06-01 184****9840

    学习了谢谢分享。

    0

  9. 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