Hypertension：失眠能显著增加高血压风险

2015-01-28 小田译医学论坛网

四川大学华西医院唐向东等的一项研究显示，入睡时间超过14分钟的失眠者面临着高血压风险增加。该研究2015年1月26日在线发表于美国心脏学会(AHA)旗下《高血压》(Hypertension)杂志。研究者们对219例长期失眠者和96例睡眠正常者进行了研究，这些受试者平均年龄为40岁，超过60%为女性。以睡眠困难超过6个月定义为长期失眠。受试者接受了一晚的睡眠实验室睡眠情况监测，第二天开始白天多次小

四川大学华西医院唐向东等的一项研究显示，入睡时间超过14分钟的失眠者面临着高血压风险增加。该研究2015年1月26日在线发表于美国心脏学会(AHA)旗下《高血压》(Hypertension)杂志上。

研究者们对219例长期失眠者和96例睡眠正常者进行了研究，这些受试者平均年龄为40岁，超过60%为女性。以睡眠困难超过6个月定义为长期失眠。受试者接受了一晚的睡眠实验室睡眠情况监测，第二天开始白天多次小睡潜伏实验(Multiple Sleep Latency Test，MSLT)。监测内容包括每隔两小时(9 a.m.，11 a.m.，1 p.m. 和3 p.m.)的4个20分钟的小睡机会。半数受试者在14分钟或以内的时间入睡，另一半的受试者需在14分钟以上的时间入睡，那些用14分钟以上时间入睡的情况为反应过度。。

结果显示，校正年龄，性别，体重指数，睡眠呼吸暂停、糖尿病、吸烟、酒精和咖啡摄入等混杂因素后，与睡眠正常者相比，MSLT评分高于14分钟的长期失眠者患高血压风险增加了3倍(OR=3.27，95%CI：1.20-8.96)，MSLT评分高于17分钟的受试者这一风险增加了4倍(OR =4.33，95%CI：1.48-12.68)。

夜间睡眠障碍被视为传统意义上的失眠，但若干研究证明失眠是24小时觉醒的一种状态。与生理觉醒相关的失眠显著增加高血压风险。研究者表示，在睡眠正常者中用的诸如打盹、喝咖啡或其他缓解疲劳的兴奋剂并不适用于失眠者，而过度喝咖啡还会使失眠者的这种情况更为严重。

原始出处：
Li Y, Vgontzas AN, Fernandez-Mendoza J, Bixler EO, Sun Y, Zhou J, Ren R, Li T, Tang X.Insomnia With Physiological Hyperarousal Is Associated With Hypertension.Hypertension. 2015 Jan 26. pii: HYPERTENSIONAHA.114.04604.

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2016-01-16 medsic

已收藏，

140 0
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2016-01-16 medsic

已收藏，

163 0
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2016-01-16 medsic

了解，

177 0
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2016-01-16 medsic

了解，

159 0
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2016-01-16 medsic

这样的话，医生是不是就不应该夜班？

211 0
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2015-06-18 12498ebem19暂无昵称

#TENS#

116 0
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2015-07-09 cmn

中国学者

186 0
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2015-12-22 feather89

#PE#

55 0
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2015-02-17 chinayinhan

已阅

134 0
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2015-01-30 jambiya

#Hypertension#

66 0

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