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Neurology:阿尔茨海默症早期,女性较男性语言记忆力更强

2016-03-17 QQduhp 译 MedSci原创

美国大约有530万人患有阿尔茨海默症,其中女性患者约有310万名。 记忆力减退是患者最早表现出的症状,随着疾病的进展恶化。 研究表明,一般来说,女性比男性的文字记忆能力更强。也就是说,女性的词汇记忆和语言组织能力更强。 爱因斯坦医学院Erin E.Sundermann博士和同事着手探究阿尔茨海默症男性及女性患者在患病早期文字记忆能力的差异。 研究人员指出,识别男女文字记忆能力的性别差异是十分重要的

美国大约有530万人患有阿尔茨海默症,其中女性患者约有310万名。 

记忆力减退是患者最早表现出的症状,并随着疾病的进展而恶化。 

研究表明,一般来说,女性比男性的文字记忆能力更强。也就是说,女性的词汇记忆和语言组织能力更强。 

爱因斯坦医学院的Erin E.Sundermann博士和同事着手探究阿尔茨海默症男性及女性患者在患病早期文字记忆能力的差异。 

研究人员指出,识别男女文字记忆能力的性别差异是十分重要的,因为这有助于医生诊断遗忘型轻度认知障碍(aMCI)或阿尔茨海默症。他们指出,许多女性aMCI患者可能并未被诊断出来,因为女性文字记忆的优势可能掩盖其潜在的神经退化疾病进程,特别是在疾病早期阶段。 

他们对235名患有阿尔茨海默症或其他神经退行性疾病患者、694名 aMCI患者和379名没有记忆或思考问题的民众进行了调查。所有民众均接受RAVLT检查和脑成像检查。研究人员还比较了参与者大脑海马体的体积。

研究人员发现,轻中度海马体萎缩的民众中,女性的语言记忆能力较男性强,海马体重度萎缩的男性和女性语言记忆能力无明显差异。此外,研究人员发现,海马体轻中度萎缩的aMCI中,女性在语言记忆测试中较男性得分高,但海马体重度萎缩的aMCI男性和女性患者语言记忆测试得分无明显差异。 

总之,研究人员认为,在阿尔茨海默症早期,尽管都存在轻到中度的海马体萎缩,女性较男性仍有语言记忆优势。 

研究人员认为,他们需要进行更进一步的研究以探究女性aMCI患者的语言记忆优势是否掩盖其潜在的神经退行性疾病。

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    2016-09-22 yinhl1978
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    2016-03-19 yangjxjc
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美国阿尔茨海默症患者约47万人。大多数患者的首发患病表现为轻度认知功能障碍。这是痴呆表现的前兆且极大增加民众患阿尔茨海默症的风险,并且可在未来几个月或几年后迅速恶化。在当今研究中,爱因斯坦医学院和蒙蒂菲奥里医疗系统的研究人员着手探究慢性压力与遗忘型轻度认知障碍(aMCI,最常见的认知障碍,主要表现为记忆力减退)之间的联系。 研究人员对EAS中507名参与人员进行探究,并深入分析相应数据。 自199

Brain:从大脑炎症中发现阿尔茨海默症的治疗线索

一直到最近,科学家们仍认为阿尔茨海默症干扰了免疫系统,但是小鼠身上的一项新的研究显示,脑部感染或导致了阿尔茨海默症的发生,研究表明阻断调节免疫细胞的一种蛋白或是停止这种脑萎缩性疾病进展的一种方法,该研究结果在线发表于Brain。

Behav Brain Res:男性的方向感较女性更强

既往的研究表明,若接受特定的空间任务,则男人比女人有更好的表现。但目前尚不清楚性激素、文化背景和其他因素等在其中发挥的作用。 挪威科技大学神经科Carl Pintzka和同事研究的目的是探究男性和女性大脑方向感的差异。 通过使用3 D眼镜和一个操纵杆,参与者需要在一个非常大的虚拟迷宫中确认方向,同时使用fMRI记录下他们的大脑活动。 活动开始之前,18名男性和18位女性花费了1个小时学习迷宫的布局

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