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Current Biology:持续光照对机体的危害超乎你想象!

2016-07-15 MedSci MedSci原创

发表在Current Biology的这篇新进研究指出,如果实验小鼠长达5个月的时间内持续暴露在恒定人工照明下,则小鼠机体健康质量下降并出现不同程度的不良反应。人体内存在一种生物钟,它由大脑中视交叉上核(SCN)细胞组成,其中包含20000个神经元,并受环境昼夜节律的影响,生物钟又影响机体的生理、心理和行为变化,使机体的体温、激素释放和心率都呈周期性变化。 研究显示,环境光照成周期性变化对机体健康

发表在Current Biology的这篇新进研究指出,如果实验小鼠长达5个月的时间内持续暴露在恒定人工照明下,则小鼠机体健康质量下降并出现不同程度的不良反应。


人体内存在一种生物钟,它由大脑中视交叉上核(SCN)细胞组成,其中包含20000个神经元,并受环境昼夜节律的影响,生物钟又影响机体的生理、心理和行为变化,使机体的体温、激素释放和心率都呈周期性变化。 

研究显示,环境光照成周期性变化对机体健康至关重要。环境光照紊乱会导致机体健康受损,并出现一系列健康问题,例如炎性免疫系统的激活、肌肉萎缩、骨质疏松症早期表现。当研究人员对实验小鼠由持续光照转为黑暗环境条件时,他们发现小鼠出现的不良反应减轻或消失。

Meijer博士和同事为了探究昼夜节律对小鼠健康的影响,他们收集了持续24周光照的小鼠的机体相关健康参数。他们发现,持续光照使得实验小鼠大脑SCN正常活动削弱70%。通过进行强度测试,他们发现,破坏昼夜节律会导致小鼠骨骼肌功能减退、骨骼强度下降并出现促炎症趋势。恢复小鼠昼夜节律时长达2周便可减少小鼠出现的不良反应。

研究人员指出,随着生命的进化,昼夜节律对机体健康至关重要,研究人员将针对昼夜节律对人类免疫系统的影响进行深入分析调查并尽可能通过调节光照促进患者机体健康。尤其是对于生活在污染较严重地区的民众,由于雾霾较重,他们接受光照的时间和强度也会改变,研究人员将对这些问题进行更进一步的研究。

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    2017-01-28 sunylz
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    2016-08-28 ylzr123

    深度好文,值得学习,赞!

    0

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    2016-08-27 ylzr123

    好文,值得学习,赞一个。

    0

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    2016-08-06 oo902

    持续光照

    0

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    2016-07-17 TZF0807

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