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Stroke: FAST-ED量表可用来识别大血管闭塞性卒中患者

2016-10-29 MedSci MedSci原创

背景:大血管闭塞卒中患者(LVOS)可以更好地通过直接转移到血管内中心治疗,避免在初级及综合卒中中心延误。然而,准确的卒中分流仍然具有挑战性。研究者的目的是开发一个简单的量表来识别LVOS。方法:FAST-ED量表是基于美国国立卫生院卒中量表(NIHSS)对LVOS有较高的预测价值,并且在STOPStroke队列中进行验证,其中患者在脑卒中发病24小时内行CT血管造影。LVOS被完全闭塞包括颈内动

背景:大血管闭塞卒中患者(LVOS)可以更好地通过直接转移到血管内中心治疗,避免在初级及综合卒中中心延误。然而,准确的卒中分流仍然具有挑战性。研究者的目的是开发一个简单的量表来识别LVOS。

方法:FAST-ED量表是基于美国国立卫生院卒中量表(NIHSS)对LVOS有较高的预测价值,并且在STOPStroke队列中进行验证,其中患者在脑卒中发病24小时内行CT血管造影。LVOS被完全闭塞包括颈内动脉颅内段,大脑中动脉M1,大脑中动脉2或基底动脉。排除部分,双侧,前+后循环闭塞的患者。分别比较NIHSS分数,快速评价动脉闭塞(RACE)量表和辛辛那提院前卒中严重程度量表(CPSS)与FAST-ED量表的接受者操作特性曲线、灵敏度、特异性、阳性预测值和阴性预测值。

结果:727例患者中,240(33%)符合LVO的条件。FAST-ED与 NIHSS评分预测LVO的准确性一致,准确度高于RACE及CPSS(ROC曲线:FAST-ED = 0.81;NIHSS评分= 0.80,P = 0.28;RACE= 0.77,P = 0.02;和CPSS = 0.75,P = 0.002)。FAST-ED≥4 ,RACE≥5,CPSS≥2的敏感性分别为0.60,0.55,0.56特异性分别为0.89,0.87,0.85阳性预测值分别0.72,0.68,0.65阴性预测值为分别0.82,0.79和0.78。

结论:如果能在该领域的成功验证,FAST-ED是一个简单的量表,医疗急救专业人员可以此量表来识别LVOS,使患者快速分流。

原始出处:

Lima FO, Silva GS, et al. Field Assessment Stroke Triage for Emergency Destination: A Simple and Accurate Prehospital Scale to Detect Large Vessel Occlusion Strokes. Stroke. 2016 Aug


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    2017-06-05 JR19860219
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    2016-12-14 kkunny
  5. [GetPortalCommentsPageByObjectIdResponse(id=1710946, encodeId=a24c1e1094650, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Tue Jul 18 19:39:00 CST 2017, time=2017-07-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2009833, encodeId=35c320098332d, content=<a href='/topic/show?id=467789803a9' target=_blank style='color:#2F92EE;'>#血管闭塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89803, encryptionId=467789803a9, topicName=血管闭塞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=827b160, createdName=cnxcy, createdTime=Fri Apr 21 00:39:00 CST 2017, time=2017-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2016031, encodeId=1b4920160318c, content=<a href='/topic/show?id=bb11e25425' target=_blank style='color:#2F92EE;'>#FAST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7254, encryptionId=bb11e25425, topicName=FAST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=20b5274, createdName=JR19860219, createdTime=Mon Jun 05 23:39:00 CST 2017, time=2017-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706107, encodeId=9efb1e06107b6, content=<a href='/topic/show?id=7f6443986ec' target=_blank style='color:#2F92EE;'>#大血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43986, encryptionId=7f6443986ec, topicName=大血管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=caff31165455, createdName=kkunny, createdTime=Wed Dec 14 23:39:00 CST 2016, time=2016-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1815189, encodeId=ddaa1815189e7, content=<a href='/topic/show?id=5f519e1848c' target=_blank style='color:#2F92EE;'>#闭塞性卒中#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97184, encryptionId=5f519e1848c, topicName=闭塞性卒中)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf1d2500084, createdName=1249884fm87暂无昵称, createdTime=Mon Sep 11 07:39:00 CST 2017, time=2017-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2057923, encodeId=a72d205e92378, content=<a href='/topic/show?id=3836e24819' target=_blank style='color:#2F92EE;'>#FAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7248, encryptionId=3836e24819, topicName=FAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=872f168, createdName=gracezdd, createdTime=Thu Aug 24 02:39:00 CST 2017, time=2017-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1720136, encodeId=3bb41e201364b, content=<a href='/topic/show?id=915c3604e6b' target=_blank style='color:#2F92EE;'>#卒中患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36047, encryptionId=915c3604e6b, topicName=卒中患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=940232842333, createdName=wangyang7969, createdTime=Sun Jan 08 06:39:00 CST 2017, time=2017-01-08, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1710946, encodeId=a24c1e1094650, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Tue Jul 18 19:39:00 CST 2017, time=2017-07-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2009833, encodeId=35c320098332d, content=<a href='/topic/show?id=467789803a9' target=_blank style='color:#2F92EE;'>#血管闭塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89803, encryptionId=467789803a9, topicName=血管闭塞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=827b160, createdName=cnxcy, createdTime=Fri Apr 21 00:39:00 CST 2017, time=2017-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2016031, encodeId=1b4920160318c, content=<a href='/topic/show?id=bb11e25425' target=_blank style='color:#2F92EE;'>#FAST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7254, encryptionId=bb11e25425, topicName=FAST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=20b5274, createdName=JR19860219, createdTime=Mon Jun 05 23:39:00 CST 2017, time=2017-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706107, encodeId=9efb1e06107b6, content=<a href='/topic/show?id=7f6443986ec' target=_blank style='color:#2F92EE;'>#大血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43986, encryptionId=7f6443986ec, topicName=大血管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=caff31165455, createdName=kkunny, createdTime=Wed Dec 14 23:39:00 CST 2016, time=2016-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1815189, encodeId=ddaa1815189e7, content=<a href='/topic/show?id=5f519e1848c' target=_blank style='color:#2F92EE;'>#闭塞性卒中#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97184, encryptionId=5f519e1848c, topicName=闭塞性卒中)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf1d2500084, createdName=1249884fm87暂无昵称, createdTime=Mon Sep 11 07:39:00 CST 2017, time=2017-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2057923, encodeId=a72d205e92378, content=<a href='/topic/show?id=3836e24819' target=_blank style='color:#2F92EE;'>#FAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7248, encryptionId=3836e24819, topicName=FAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=872f168, createdName=gracezdd, createdTime=Thu Aug 24 02:39:00 CST 2017, time=2017-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1720136, encodeId=3bb41e201364b, content=<a href='/topic/show?id=915c3604e6b' target=_blank style='color:#2F92EE;'>#卒中患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36047, encryptionId=915c3604e6b, topicName=卒中患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=940232842333, createdName=wangyang7969, createdTime=Sun Jan 08 06:39:00 CST 2017, time=2017-01-08, status=1, ipAttribution=)]
    2017-08-24 gracezdd
  7. [GetPortalCommentsPageByObjectIdResponse(id=1710946, encodeId=a24c1e1094650, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Tue Jul 18 19:39:00 CST 2017, time=2017-07-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2009833, encodeId=35c320098332d, content=<a href='/topic/show?id=467789803a9' target=_blank style='color:#2F92EE;'>#血管闭塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89803, encryptionId=467789803a9, topicName=血管闭塞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=827b160, createdName=cnxcy, createdTime=Fri Apr 21 00:39:00 CST 2017, time=2017-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2016031, encodeId=1b4920160318c, content=<a href='/topic/show?id=bb11e25425' target=_blank style='color:#2F92EE;'>#FAST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7254, encryptionId=bb11e25425, topicName=FAST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=20b5274, createdName=JR19860219, createdTime=Mon Jun 05 23:39:00 CST 2017, time=2017-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706107, encodeId=9efb1e06107b6, content=<a href='/topic/show?id=7f6443986ec' target=_blank style='color:#2F92EE;'>#大血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43986, encryptionId=7f6443986ec, topicName=大血管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=caff31165455, createdName=kkunny, createdTime=Wed Dec 14 23:39:00 CST 2016, time=2016-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1815189, encodeId=ddaa1815189e7, content=<a href='/topic/show?id=5f519e1848c' target=_blank style='color:#2F92EE;'>#闭塞性卒中#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97184, encryptionId=5f519e1848c, topicName=闭塞性卒中)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf1d2500084, createdName=1249884fm87暂无昵称, createdTime=Mon Sep 11 07:39:00 CST 2017, time=2017-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2057923, encodeId=a72d205e92378, content=<a href='/topic/show?id=3836e24819' target=_blank style='color:#2F92EE;'>#FAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7248, encryptionId=3836e24819, topicName=FAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=872f168, createdName=gracezdd, createdTime=Thu Aug 24 02:39:00 CST 2017, time=2017-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1720136, encodeId=3bb41e201364b, content=<a href='/topic/show?id=915c3604e6b' target=_blank style='color:#2F92EE;'>#卒中患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36047, encryptionId=915c3604e6b, topicName=卒中患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=940232842333, createdName=wangyang7969, createdTime=Sun Jan 08 06:39:00 CST 2017, time=2017-01-08, status=1, ipAttribution=)]
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