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BMC Res Notes:日本中老年人群中,亚临床听力损失与恢复性睡眠相关性研究

2018-04-12 AlexYang MedSci原创

听力损失也许与某些睡眠异常相关。之前,有研究人员报道了亚临床听力损失(SHL)在睡眠长于8小时的日本人群中更加流行;然而,潜在的机制却并不明晰。因此,最近有研究人员调查了SHL与自我报道的恢复性睡眠(RS)之间的相关性,并通过调查问卷进行评估。研究包括了年龄在40-69岁且没有明显的或者诊断性听力损失的33888名参与者(男性20225名;女性13663名)。研究发现,在4000Hz时,RS个体比

听力损失也许与某些睡眠异常相关。之前,有研究人员报道了亚临床听力损失(SHL)在睡眠长于8小时的日本人群中更加流行;然而,潜在的机制却并不明晰。因此,最近有研究人员调查了SHL与自我报道的恢复性睡眠(RS)之间的相关性,并通过调查问卷进行评估。研究包括了年龄在40-69岁且没有明显的或者诊断性听力损失的33888名参与者(男性20225名;女性13663名)。

研究发现,在4000Hz时,RS个体比例在双边SHL中要比单边SHL显著更高,完整听力在1000Hz时没有上述群体差异,并且与年龄无关(P<0.0001,双向方差分析)。多变量逻辑回归分析表明双边SHL在4000Hz,而不是1000Hz时与RS显著相关,并且该相关性与潜在的相关混杂因素,包括年龄、性别和心血管代谢风险因素均无关。

最后,研究人员指出,他们的研究扩展了他们早期的研究工作,并且阐释了在中老年人群中,早期听力损伤与令人满意的睡眠之间未预料到的相关性。考虑到可能的潜在机制和临床相关性,上述相关性需要更进一步的确定。

原始出处:


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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=305272, encodeId=0ce13052e204, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmhead/Q3auHgzwzM6P57Bs8gOPaY1cQP9lIia0lmZOEXraGaoicqNToIslXDKw/0, createdBy=7a041951742, createdName=衣带渐宽, createdTime=Fri Apr 13 07:01:49 CST 2018, time=2018-04-13, status=1, ipAttribution=)]
    2018-04-20 祝您健康

    学习学习

    0

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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=305272, encodeId=0ce13052e204, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmhead/Q3auHgzwzM6P57Bs8gOPaY1cQP9lIia0lmZOEXraGaoicqNToIslXDKw/0, createdBy=7a041951742, createdName=衣带渐宽, createdTime=Fri Apr 13 07:01:49 CST 2018, time=2018-04-13, status=1, ipAttribution=)]
    2018-04-15 飘飘爱

    很好

    0

  7. 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  8. 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    2018-04-14 ysjykql
  9. 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    2018-04-13 衣带渐宽

    学习

    0

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因为新生儿听力筛选过程,单边听力损失(UHL)儿童在很小的年龄时就能够被诊断。从传统的观点看,这些儿童在听力和语言发展过程中会存在障碍风险。儿童早期-出生前几个月的临时群体可利用信息很少。最近,有研究人员在一个早期鉴定的患有UHL的儿童临时性群体中调查了听力和语言学习结果,并且与他们的同龄的学前年龄的轻度双边听力损失和正常听力损失儿童进行了比较。研究人员在4年时间内搜集了患有单边、双边听力损失和具

Maturitas:在老年人中,言语和高频率听力损失以及抑郁、焦虑和压力之间的相关性研究

年龄相关的听力损失(ARHL)和抑郁被认为是导致老年人残疾的主导原因。最近,有研究人员进行了一个代表性的研究,调查了老年人中言语严重度和高频听力损失与抑郁、焦虑和压力之间的关系。研究包括了151名参与者(73名男性和78名女性,平均年龄为64.44±10.77岁)。研究人员根据他们的更好的耳朵听力(0.5, 1, 2和4kHz)和高频率(6和8kHz)听力阈值,将他们分成了3个小组:正常听力组、轻

Sci Rep:IDH2功能丧失能够加速年龄相关的听力损失

异柠檬酸脱氢酶(IDH)2参与了TCA循环并且能够催化异柠檬酸到α-酮戊二酸以及NADP+到NADPH的转化。在线粒体中,IDH2通过提供NADPH到谷胱甘肽还原酶(GSR)和硫氧还蛋白还原酶(TXNRD2),同样在保护线粒体组分免受氧化胁迫上具有重要的作用。最近,有研究人员报道了Idh2功能的丧失能够加速年龄相关的听力损失,这也是雄性小鼠最为常见的听力损伤形式。并且在24个月大的Idh2-/-小

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