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Ann Intern Med:胃食管反流病内镜筛查建议

2012-12-07 小哲 编译 Ann Intern Med

  上消化道内镜筛查常在诊断和管理胃食管反流病(gastroesophageal reflux disease,GERD)患者时使用。12月4日,美国《内科学年鉴(Annals of Internal Medicine)》刊载的一项指南指出,内科医生对低风险GERD患者过度进行上消化道内镜检查,没有促进患者转归反而导致更高的医疗花费。[Ann In

  上消化道内镜筛查常在诊断和管理胃食管反流病(gastroesophageal reflux disease,GERD)患者时使用。12月4日,美国《内科学年鉴(Annals of Internal Medicine)》刊载的一项指南指出,内科医生对低风险GERD患者过度进行上消化道内镜检查,没有促进患者转归反而导致更高的医疗花费。[Ann Intern Med. 2012;157:808-816.]

  内镜检查是消化道疾病诊断和管理的重大突破。然而,不恰当的检查不但没有益处反而可能增加医疗成本。回顾往期研究数据表明,上消化道内镜检查只在少数情况下用于胃食管反流病的诊断。

  第一,指南作者推荐所有胃灼热和GERD的男性、女性患者出现吞咽困难、出血、贫血、体重减轻和再发性呕吐时进行上消化道内镜检查。作者说,在这些情况下上消化道内镜检查是有价值的,因为可以识别临床必要的信息,比如胃癌或食管癌、前肠出血病灶,以及食管或幽门狭窄。

  第二,作者推荐下列患者应进行上消化道内镜检查:持续4~8周质子泵抑制剂(proton pump inhibitor,PPI)治疗的GERD男性、女性患者;经过2个月PPI治疗后评估康复并且排除巴雷特食管(Barrett's esophagus)的重度腐蚀性食管炎的男性、女性患者;有食管狭窄病史并且有周期性吞咽困难症状的男性、女性患者。

  第三,指南推荐下述人群进行上消化道内镜检查:50岁以上并有夜间反流症、吸烟和体质指数偏高等风险因子的慢性GERD男性患者需检查是否有食管癌和巴雷特食管;对于有巴雷特食管病史的男性、女性患者进行监测评估,已经确诊为巴雷特食管的患者建议每3~5年进行上消化道内镜复检,出现轻度至重度的异型增生时,由于癌变风险增加,建议定期进行内镜筛查。


Upper Endoscopy for Gastroesophageal Reflux Disease: Best Practice Advice From the Clinical Guidelines Committee of the American College of Physicians 



    

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  5. [GetPortalCommentsPageByObjectIdResponse(id=2046105, encodeId=f305204610552, content=<a href='/topic/show?id=010b3e767b2' target=_blank style='color:#2F92EE;'>#反流病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37767, encryptionId=010b3e767b2, topicName=反流病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8dba135, createdName=xuyong523, createdTime=Sat Oct 05 07:24:00 CST 2013, time=2013-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1948501, encodeId=7cca19485016a, content=<a href='/topic/show?id=87828339e7a' target=_blank style='color:#2F92EE;'>#胃食管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83397, encryptionId=87828339e7a, topicName=胃食管)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=循证小兵, createdTime=Thu Oct 17 11:24:00 CST 2013, time=2013-10-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1260658, encodeId=2000126065870, content=<a href='/topic/show?id=2f71834056f' target=_blank style='color:#2F92EE;'>#胃食管反流#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83405, encryptionId=2f71834056f, topicName=胃食管反流)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=44a360, createdName=jklm09, createdTime=Sun Dec 09 07:24:00 CST 2012, time=2012-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1261822, encodeId=355a126182200, content=<a href='/topic/show?id=0ceb30545e0' target=_blank style='color:#2F92EE;'>#内镜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30545, encryptionId=0ceb30545e0, topicName=内镜)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c30265, createdName=jiafufeng@yaho, createdTime=Sun Dec 09 07:24:00 CST 2012, time=2012-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1437014, encodeId=4a60143e014ae, content=<a href='/topic/show?id=0e311010591a' target=_blank style='color:#2F92EE;'>#食管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101059, encryptionId=0e311010591a, topicName=食管)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Sun Dec 09 07:24:00 CST 2012, time=2012-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1571537, encodeId=087915e15373f, content=<a href='/topic/show?id=41e33e76137' target=_blank style='color:#2F92EE;'>#反流#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37761, encryptionId=41e33e76137, topicName=反流)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=220d15750403, createdName=feifers, createdTime=Sun Dec 09 07:24:00 CST 2012, time=2012-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1605863, encodeId=267016058636c, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Sun Dec 09 07:24:00 CST 2012, time=2012-12-09, status=1, ipAttribution=)]
    2012-12-09 zhouqu_8
  6. [GetPortalCommentsPageByObjectIdResponse(id=2046105, encodeId=f305204610552, content=<a href='/topic/show?id=010b3e767b2' target=_blank style='color:#2F92EE;'>#反流病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37767, encryptionId=010b3e767b2, topicName=反流病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8dba135, createdName=xuyong523, createdTime=Sat Oct 05 07:24:00 CST 2013, time=2013-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1948501, encodeId=7cca19485016a, content=<a href='/topic/show?id=87828339e7a' target=_blank style='color:#2F92EE;'>#胃食管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83397, encryptionId=87828339e7a, topicName=胃食管)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=循证小兵, createdTime=Thu Oct 17 11:24:00 CST 2013, time=2013-10-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1260658, encodeId=2000126065870, content=<a href='/topic/show?id=2f71834056f' target=_blank style='color:#2F92EE;'>#胃食管反流#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83405, encryptionId=2f71834056f, topicName=胃食管反流)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=44a360, createdName=jklm09, createdTime=Sun Dec 09 07:24:00 CST 2012, time=2012-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1261822, encodeId=355a126182200, content=<a href='/topic/show?id=0ceb30545e0' target=_blank style='color:#2F92EE;'>#内镜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30545, encryptionId=0ceb30545e0, topicName=内镜)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c30265, createdName=jiafufeng@yaho, createdTime=Sun Dec 09 07:24:00 CST 2012, time=2012-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1437014, encodeId=4a60143e014ae, content=<a href='/topic/show?id=0e311010591a' target=_blank style='color:#2F92EE;'>#食管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101059, encryptionId=0e311010591a, topicName=食管)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Sun Dec 09 07:24:00 CST 2012, time=2012-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1571537, encodeId=087915e15373f, content=<a href='/topic/show?id=41e33e76137' target=_blank style='color:#2F92EE;'>#反流#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37761, encryptionId=41e33e76137, topicName=反流)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=220d15750403, createdName=feifers, createdTime=Sun Dec 09 07:24:00 CST 2012, time=2012-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1605863, encodeId=267016058636c, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Sun Dec 09 07:24:00 CST 2012, time=2012-12-09, status=1, ipAttribution=)]
    2012-12-09 feifers
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