Baidu
map

BMJ:与儿童哮喘相关的空气及家庭因素研究

2020-08-22 MedSci原创 MedSci原创

PM2.5是诱发儿童哮喘和持续性喘息的重要风险因素,其他相关的危险因素包括父母哮喘、父母社会经济地位和孕期吸烟

近日研究人员考察了与儿童哮喘和持续性喘息发作相关的空气污染和家庭相关危险因素。

 

研究为全国病例对照研究,在丹麦开展,参与者为出生于1997年至2014年的丹麦儿童,随访期为1-15岁或哮喘和持续性喘息发作。

研究发现,父母患有哮喘(校正后的危险比为2.29)和怀孕期间母亲吸烟(1.20)儿童的哮喘发病率较高,而教育程度高(0.72)和收入高的父母(0.85),其子女哮喘发病率较低。

暴露于颗粒物质≤2.5 μm (PM2.5)、≤10μm (PM10)和硝酸盐环境与哮喘和持续性喘息风险增加有关,PM2.5、PM10以及二氧化氮污染物浓度每增加5μg/m3的,相应的风险比为1.05、1.04和1.04。

在不同的模型和敏感性分析中,只有PM2.5浓度与哮喘和持续性喘息风险呈正相关。

研究发现,PM2.5是诱发儿童哮喘和持续性喘息的重要风险因素,其他相关的危险因素包括父母哮喘、父母社会经济地位和孕期吸烟。

原始出处:

Gitte J Holstet al. Air pollution and family related determinants of asthma onset and persistent wheezing in children: nationwide case-control study. BMJ,August 19, 2020.

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1849083, encodeId=88d91849083a9, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sat Feb 27 05:53:52 CST 2021, time=2021-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=908505, encodeId=c1a6908505f4, content=社会经济地位,使家庭暴露在环境恶劣、污染、营养不良的情况下的比例也更多些。, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201214/b3170121d995432ea306ae3a7809cc05/2cfb236f361b4d3c80ef8fdef4301832.jpg, createdBy=8ad35400531, createdName=潛心學習者, createdTime=Wed Dec 16 11:16:41 CST 2020, time=2020-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=812781, encodeId=cb70812e8195, content=哮喘发作与环境因素密切相关,已有多项研究证实。<a href='/topic/show?id=052d399242a' target=_blank style='color:#2F92EE;'>#哮喘#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=182, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39924, encryptionId=052d399242a, topicName=哮喘)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Mon Aug 24 18:12:16 CST 2020, time=2020-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1295971, encodeId=8eab12959e18a, content=<a href='/topic/show?id=5d41282361d' target=_blank style='color:#2F92EE;'>#儿童哮喘#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28236, encryptionId=5d41282361d, topicName=儿童哮喘)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a885259, createdName=yourmama, createdTime=Mon Aug 24 00:53:52 CST 2020, time=2020-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=812490, encodeId=f1c78124902a, content=不错 点赞收藏学习起来, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLNibQE85E0sLrn9iasdRSCTB5e7ow6EC5ETpKiamzthjhFVNLpj6qKIeianjHUhQl32fPQtkdsiatFfLQ/132, createdBy=4d852205064, createdName=红豆豆豆豆, createdTime=Sun Aug 23 19:52:16 CST 2020, time=2020-08-23, status=1, ipAttribution=)]
    2021-02-27 gaoxiaoe
  2. [GetPortalCommentsPageByObjectIdResponse(id=1849083, encodeId=88d91849083a9, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sat Feb 27 05:53:52 CST 2021, time=2021-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=908505, encodeId=c1a6908505f4, content=社会经济地位,使家庭暴露在环境恶劣、污染、营养不良的情况下的比例也更多些。, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201214/b3170121d995432ea306ae3a7809cc05/2cfb236f361b4d3c80ef8fdef4301832.jpg, createdBy=8ad35400531, createdName=潛心學習者, createdTime=Wed Dec 16 11:16:41 CST 2020, time=2020-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=812781, encodeId=cb70812e8195, content=哮喘发作与环境因素密切相关,已有多项研究证实。<a href='/topic/show?id=052d399242a' target=_blank style='color:#2F92EE;'>#哮喘#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=182, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39924, encryptionId=052d399242a, topicName=哮喘)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Mon Aug 24 18:12:16 CST 2020, time=2020-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1295971, encodeId=8eab12959e18a, content=<a href='/topic/show?id=5d41282361d' target=_blank style='color:#2F92EE;'>#儿童哮喘#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28236, encryptionId=5d41282361d, topicName=儿童哮喘)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a885259, createdName=yourmama, createdTime=Mon Aug 24 00:53:52 CST 2020, time=2020-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=812490, encodeId=f1c78124902a, content=不错 点赞收藏学习起来, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLNibQE85E0sLrn9iasdRSCTB5e7ow6EC5ETpKiamzthjhFVNLpj6qKIeianjHUhQl32fPQtkdsiatFfLQ/132, createdBy=4d852205064, createdName=红豆豆豆豆, createdTime=Sun Aug 23 19:52:16 CST 2020, time=2020-08-23, status=1, ipAttribution=)]
    2020-12-16 潛心學習者

    社会经济地位,使家庭暴露在环境恶劣、污染、营养不良的情况下的比例也更多些。

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1849083, encodeId=88d91849083a9, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sat Feb 27 05:53:52 CST 2021, time=2021-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=908505, encodeId=c1a6908505f4, content=社会经济地位,使家庭暴露在环境恶劣、污染、营养不良的情况下的比例也更多些。, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201214/b3170121d995432ea306ae3a7809cc05/2cfb236f361b4d3c80ef8fdef4301832.jpg, createdBy=8ad35400531, createdName=潛心學習者, createdTime=Wed Dec 16 11:16:41 CST 2020, time=2020-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=812781, encodeId=cb70812e8195, content=哮喘发作与环境因素密切相关,已有多项研究证实。<a href='/topic/show?id=052d399242a' target=_blank style='color:#2F92EE;'>#哮喘#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=182, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39924, encryptionId=052d399242a, topicName=哮喘)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Mon Aug 24 18:12:16 CST 2020, time=2020-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1295971, encodeId=8eab12959e18a, content=<a href='/topic/show?id=5d41282361d' target=_blank style='color:#2F92EE;'>#儿童哮喘#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28236, encryptionId=5d41282361d, topicName=儿童哮喘)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a885259, createdName=yourmama, createdTime=Mon Aug 24 00:53:52 CST 2020, time=2020-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=812490, encodeId=f1c78124902a, content=不错 点赞收藏学习起来, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLNibQE85E0sLrn9iasdRSCTB5e7ow6EC5ETpKiamzthjhFVNLpj6qKIeianjHUhQl32fPQtkdsiatFfLQ/132, createdBy=4d852205064, createdName=红豆豆豆豆, createdTime=Sun Aug 23 19:52:16 CST 2020, time=2020-08-23, status=1, ipAttribution=)]
    2020-08-24 仁心济世

    哮喘发作与环境因素密切相关,已有多项研究证实。#哮喘#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1849083, encodeId=88d91849083a9, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sat Feb 27 05:53:52 CST 2021, time=2021-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=908505, encodeId=c1a6908505f4, content=社会经济地位,使家庭暴露在环境恶劣、污染、营养不良的情况下的比例也更多些。, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201214/b3170121d995432ea306ae3a7809cc05/2cfb236f361b4d3c80ef8fdef4301832.jpg, createdBy=8ad35400531, createdName=潛心學習者, createdTime=Wed Dec 16 11:16:41 CST 2020, time=2020-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=812781, encodeId=cb70812e8195, content=哮喘发作与环境因素密切相关,已有多项研究证实。<a href='/topic/show?id=052d399242a' target=_blank style='color:#2F92EE;'>#哮喘#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=182, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39924, encryptionId=052d399242a, topicName=哮喘)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Mon Aug 24 18:12:16 CST 2020, time=2020-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1295971, encodeId=8eab12959e18a, content=<a href='/topic/show?id=5d41282361d' target=_blank style='color:#2F92EE;'>#儿童哮喘#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28236, encryptionId=5d41282361d, topicName=儿童哮喘)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a885259, createdName=yourmama, createdTime=Mon Aug 24 00:53:52 CST 2020, time=2020-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=812490, encodeId=f1c78124902a, content=不错 点赞收藏学习起来, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLNibQE85E0sLrn9iasdRSCTB5e7ow6EC5ETpKiamzthjhFVNLpj6qKIeianjHUhQl32fPQtkdsiatFfLQ/132, createdBy=4d852205064, createdName=红豆豆豆豆, createdTime=Sun Aug 23 19:52:16 CST 2020, time=2020-08-23, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1849083, encodeId=88d91849083a9, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sat Feb 27 05:53:52 CST 2021, time=2021-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=908505, encodeId=c1a6908505f4, content=社会经济地位,使家庭暴露在环境恶劣、污染、营养不良的情况下的比例也更多些。, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201214/b3170121d995432ea306ae3a7809cc05/2cfb236f361b4d3c80ef8fdef4301832.jpg, createdBy=8ad35400531, createdName=潛心學習者, createdTime=Wed Dec 16 11:16:41 CST 2020, time=2020-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=812781, encodeId=cb70812e8195, content=哮喘发作与环境因素密切相关,已有多项研究证实。<a href='/topic/show?id=052d399242a' target=_blank style='color:#2F92EE;'>#哮喘#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=182, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39924, encryptionId=052d399242a, topicName=哮喘)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Mon Aug 24 18:12:16 CST 2020, time=2020-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1295971, encodeId=8eab12959e18a, content=<a href='/topic/show?id=5d41282361d' target=_blank style='color:#2F92EE;'>#儿童哮喘#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28236, encryptionId=5d41282361d, topicName=儿童哮喘)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a885259, createdName=yourmama, createdTime=Mon Aug 24 00:53:52 CST 2020, time=2020-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=812490, encodeId=f1c78124902a, content=不错 点赞收藏学习起来, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLNibQE85E0sLrn9iasdRSCTB5e7ow6EC5ETpKiamzthjhFVNLpj6qKIeianjHUhQl32fPQtkdsiatFfLQ/132, createdBy=4d852205064, createdName=红豆豆豆豆, createdTime=Sun Aug 23 19:52:16 CST 2020, time=2020-08-23, status=1, ipAttribution=)]
    2020-08-23 红豆豆豆豆

    不错 点赞收藏学习起来

    0

相关资讯

World Allergy Organ J:哮喘成年人中鼻高反应性的患病率和激发因子研究

鼻高反应性(NHR)是各种鼻炎亚型的一种常见特征,是鼻炎的一种新的表型。据报道,三分之二的鼻炎患者忽略了特应性反应。目前,关于哮喘患者的NHR患病率数据以及激发因子数据仍旧缺乏。

Eur Respir J:哮喘患者骨质疏松和脆性骨折发病率

哮喘患者比普通人群更容易发生骨质疏松症或FF,尤其是年轻人和使用OCS和ICS的个体。

JAMA Intern Med :雷雨天前夕慢阻肺或哮喘发作增加!

近日,一项美国研究发现,雷雨天暴发前夕,哮喘和慢阻肺等呼吸道疾病急诊患者人数明显增加。研究者回顾医保数据,就1999~2012年间65岁以上有呼吸疾病者前往急诊就诊情况和当时天气情况进行了分析。

J Allergy Clin Immunol:哮喘和过敏性鼻炎患者中对TLR7/8激动剂的鼻粘膜干扰素和CCL13反应增加

急性呼吸道病毒感染是呼吸道发病和死亡的主要原因,尤其是对于已有肺部疾病如哮喘的患者。Toll样受体(TLRs)在早期病毒检测和激活呼吸道黏膜先天性免疫中起着关键作用,但目前还没有可靠、方便的方法来检测

Eur Respir J:芬兰青年男性哮喘、变应性鼻炎和特应性湿疹的长期趋势

在芬兰,年轻男性的哮喘和过敏性疾病从1960年代中期开始增加很明显。增长速度在2000年代有所放缓,并可能在2020年代趋于平稳。

BMJ:哮喘患者自我管理模式对医疗干预和生活质量的影响

哮喘患者使用定期医疗支持的自我管理可减少医疗资源使用,并改善哮喘的严重程度和生活质量

Baidu
map
Baidu
map
Baidu
map