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Chest:心房颤动和卒中的全球负担:亚洲心房颤动临床流行病学的系统评价!

2017-04-21 xing.T MedSci原创

近年来,尽管亚洲各国房颤发病率和患病率存在很大的变异,但均呈上升趋势。在医院和社区为基础的研究中,房颤患者缺血性卒中每年的风险变异在医院和社区为基础的研究中是很明显的。然而,在亚洲国家的医院研究中,华法林的使用率不到50%。

近日,胸部疾病领域权威杂志Chest杂志上发表了一篇荟萃分析文章,研究人员之前的系统评价显示在非西方队列中,特别是来自亚洲国家的队列,房颤(AF)的发病率和患病率有很大的变异性,近年来,AF的流行病学研究已有越来越多的报道。

因此,研究人员进行了一项更新的系统评价,提出了亚洲国家AF流行病学的目前知识基础。研究人员通过荟萃分析还探讨了AF发病率以及AF患者的卒中风险,采用I2检测了异质性。第三,研究了“真实世界”使用预防缺血性卒中的抗栓药物与AF之间的相关性。

研究人员最终将来自亚洲8个国家的58篇论文纳入了分析。当对医院和社区为基础的研究进行荟萃分析时,总结年度AF的发病率为5.38(95%可信区间:4.53-6.24,I2=99.5%,n=10)每1000人每年,并且AF患者缺血性卒中每年风险为3%(1.60%-4.95%,I2=99.8%,n=8)。医院和社区为基础的AF患病率分别从0.37%到3.56%和2.8%到15.8%。在AF患者缺血性卒中的患病率范围在社区和医院的研究中分别为1.9-6.0%和0.36-28.3%。在中国使用华法林相对较低(1.0-4.1 %),与日本社区为基础的研究队列相比(49.1-70.0 %)。在医院为基础的研究中华法林使用率均低于50%。

近年来,尽管亚洲各国房颤发病率和患病率存在很大的变异,但均呈上升趋势。在医院和社区为基础的研究中,房颤患者缺血性卒中每年的风险变异在医院和社区为基础的研究中是很明显的。然而,在亚洲国家的医院研究中,华法林的使用率不到50%。

原始出处:

Ying Bai,et al. The Global Burden of Atrial Fibrillation and Stroke: A Systematic Review of the Clinical Epidemiology of Atrial Fibrillation in Asia.Chest. 2017. http://journal.publications.chestnet.org/article.aspx?articleid=2622867

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    2017-07-16 Smile2680
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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Fri Apr 21 10:51:07 CST 2017, time=2017-04-21, status=1, ipAttribution=)]
  5. 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topicName=流行病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Sun Apr 23 00:30:00 CST 2017, time=2017-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1444206, encodeId=427d14442069a, content=<a href='/topic/show?id=3d9291459d1' target=_blank style='color:#2F92EE;'>#评价#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91459, encryptionId=3d9291459d1, topicName=评价)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1fee5134542, createdName=huagfeg, createdTime=Sun Apr 23 00:30:00 CST 2017, time=2017-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626835, encodeId=526f1626835d8, content=<a href='/topic/show?id=986a5101e46' target=_blank style='color:#2F92EE;'>#心房#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Fri Apr 21 10:51:07 CST 2017, time=2017-04-21, status=1, ipAttribution=)]
    2017-04-23 往日如昨

    学习了谢谢分享

    0

  6. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Fri Apr 21 10:51:07 CST 2017, time=2017-04-21, status=1, ipAttribution=)]
    2017-04-23 xugumin
  7. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Fri Apr 21 10:51:07 CST 2017, time=2017-04-21, status=1, ipAttribution=)]
    2017-04-23 huagfeg
  8. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Fri Apr 21 10:51:07 CST 2017, time=2017-04-21, status=1, ipAttribution=)]
    2017-04-23 sodoo
  9. [GetPortalCommentsPageByObjectIdResponse(id=1929314, encodeId=fe3819293146e, content=<a href='/topic/show?id=9e604625ab' target=_blank style='color:#2F92EE;'>#Chest#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4625, encryptionId=9e604625ab, topicName=Chest)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c48a270, createdName=Smile2680, createdTime=Sun Jul 16 16:30:00 CST 2017, time=2017-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1797424, encodeId=be2b1e9742454, content=<a href='/topic/show?id=e85422883b5' target=_blank style='color:#2F92EE;'>#临床流行病学#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22883, encryptionId=e85422883b5, topicName=临床流行病学)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e524260, 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Fri Apr 21 10:51:07 CST 2017, time=2017-04-21, status=1, ipAttribution=)]
    2017-04-22 flysky120

    学习有用的知识

    0

  10. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Fri Apr 21 10:51:07 CST 2017, time=2017-04-21, status=1, ipAttribution=)]
    2017-04-21 1ddf0692m34(暂无匿称)

    涨知识,学习

    0

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