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Diabetes Care:不同种族老年糖尿病的患病率分析

2015-04-13 崔倩译 MedSci原创

目的:争论围绕着中老年人糖尿病患者相应的风险因素指标。我们评估了老年糖尿病患者满足不同指标的比例,集中于种族可能引起差异,并评估人口统计学和临床特征是否可以解释这种差距。 研究设计和方法:我们对5,018名年龄67-90岁的参与者(1574名被确诊为糖尿病,3444名没有被确诊为糖尿病)进行了横断面研究,这些参与者出席参观动脉粥样硬化风险5社区(ARIC)研究(2011-2013年)。风险因素

目的:争论围绕着中老年人糖尿病患者相应的风险因素指标。我们评估了老年糖尿病患者满足不同指标的比例,集中于种族可能引起差异,并评估人口统计学和临床特征是否可以解释这种差距。

研究设计和方法:我们对5,018名年龄67-90岁的参与者(1574名被确诊为糖尿病,3444名没有被确诊为糖尿病)进行了横断面研究,这些参与者出席参观动脉粥样硬化风险5社区(ARIC)研究(2011-2013年)。风险因素指标均同时使用严格的(和不那么严格)的目标定义:糖化血红蛋白(HbA1c)水平<7%或<53毫摩尔/摩尔(<8%,<64毫摩尔/摩尔);低密度脂蛋白胆固醇(LDL-C)<100毫克/分升(<130毫克/分升);血压(BP)的<140/90毫米汞柱(<150/90毫米汞柱)。我们用泊松回归来获得流行率(PRS)。

结果:大多数老年人患有糖尿病满足严格的(和不那么严格的)目标:72%(90%)满足糖化血红蛋白,63%(86%)满足LDL-c和73%(87%)满足BP;但只有35%(68%)符合所有这三个指标。比例较高的白人满足目标。危险因素治疗的人群中,在满足严格的目标患病率的种族差异,即使调整后仍然存在:PRs(白人与黑人)为1.03(95%Cl 0.91,1.17),糖化血红蛋白为1.21(1.09,1.35),LDL-C为1.10(1.00,1.21),BP为1.28(0.99,1.66)。结果是相似的,但使用不那么严格的目标略有减弱。黑人女性不太可能比白人女性满足BP目标和所有三个风险因素;这种差异并没有在男性观察到。

结论:黑人与白人的差距在老年糖尿病患者的危险因素的控制中并没有通过人口统计或临床特征解释,女性比男性有更大的风险。这些差异的因素的深入研究是非常重要的。

原始出处

Christina M. Parrinello, Ina Rastegar, Job G. Godino, Michael D. Miedema,Kunihiro Matsushita, and Elizabeth Selvin.Prevalence of and Racial Disparities in Risk Factor Control in Older Adults With Diabetes: The Atherosclerosis Risk in Communities Study.Diabetes Care. 2015 Apr 7.

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    2015-06-11 ljjj1053

    好好学习一下

    0

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    2015-04-19 xiaoai5777

    好文章

    0

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