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密尔沃基疗法治狂犬病再获成功

2011-09-06 李宓 新华网

  美国加利福尼亚州北部的一名8岁狂犬病患者近日接受一种名为密尔沃基疗法的诱导昏迷治疗后成功康复,迄今全球已有5名未接种疫苗的狂犬病患者经这种疗法治疗后康复。   实施此次治疗的加利福尼亚大学戴维斯分校儿童医院报告说,这名8岁女童在被一只流浪猫抓伤数周后出现病毒性脑炎症状,后被诊断为因狂犬病病毒引发病毒性脑炎。于是,医生开始以密尔沃基疗法尝试挽救患儿。   这种疗法于2004年由美国研究人员推

  美国加利福尼亚州北部的一名8岁狂犬病患者近日接受一种名为密尔沃基疗法的诱导昏迷治疗后成功康复,迄今全球已有5名未接种疫苗的狂犬病患者经这种疗法治疗后康复。

  实施此次治疗的加利福尼亚大学戴维斯分校儿童医院报告说,这名8岁女童在被一只流浪猫抓伤数周后出现病毒性脑炎症状,后被诊断为因狂犬病病毒引发病毒性脑炎。于是,医生开始以密尔沃基疗法尝试挽救患儿。

  这种疗法于2004年由美国研究人员推出。根据其原理,医生用药物使这名患儿处于诱导昏迷状态,让其身体在维持基本功能的同时自行清除狂犬病病毒,并设法使她的脑部处于休眠状态以减少病毒对神经系统的伤害。

  该医院发布的新闻公报说,小女孩在诱导昏迷一星期后慢慢苏醒,目前已经恢复说话、写字能力,并能在辅助下行走。医院预计,再过一个星期该患儿就可出院。

  院方表示,实现这种理想效果的原因可能是这名患者自身的免疫系统对狂犬病病毒的抵抗力比其他患者强,也有可能是她感染的病毒毒性较弱。一些医学专家也指出,医学界还需通过进一步研究来确定密尔沃基疗法的疗效。

  由于严格执行动物疫苗接种,美国基本在狗和绝大部分猫中清除了狂犬病病毒。美国每年报告的人患狂犬病病例仅3到4例,且大多数因蝙蝠咬伤所致。全世界每年约有5万人死于狂犬病,病死率接近100%。

密尔沃基疗法详细说明(英文)Milwaukee Protocol - Medical College of Wisconsin

有关狂犬病一些小知识:

 绝大多数恐狂情绪的诱因是被网络上或实际生活中一些不负责任的或不正确的言论所误导造成的,比如,绝大多数人有着这样的错误或不准确的认识:被咬伤之后一定要在24小时以内去打疫苗,超过24小时就没用了。

    其实正确的说法是:被伤后应立即用20%的肥皂水(或者其他弱碱性清洁剂)和一定压力的流动清水交替彻底清洗、冲洗所有咬伤和抓伤处至少15分钟,然后用生理盐水(也可用清水代替)将伤口洗净,然后用无菌脱脂棉将伤口处残留液吸尽以避免在伤口处残留肥皂水或者清洁剂,然后立即用2%到3%的碘酒或75%的酒精涂擦伤口消毒,如果没有这些消毒剂,则应在按上述流程彻底清洗伤口后立即在尽量不缝合和不包扎伤口(如果没有伤到大血管的话)的情况下就近前往正规接种点看医生,在医生再对伤口作仍有必要的妥当处理后,在医生认为有必要且可行的情况下应尽快在伤口周围浸润注射免疫球蛋白或抗血清后接种狂犬病疫苗以及进行其它可能必要的处理措施,而不是说只要在24小时内打疫苗就一定保险!而且在医生认为有必要且可行的情况下应尽快在伤口周围浸润注射免疫球蛋白或抗血清,这样不仅可以在病毒侵入神经末梢前将其中和,而且能激活局部T细胞介导的免疫反应,对预防狂犬病至关重要!对于被伤后超过24小时甚至多年的人来说,如果自上次被伤以来还没有接种过疫苗而且又无法判定当初伤人的动物不会带毒(可用“十日观察法”判断被感染的可能性),只要还没有发病,都应立即妥善处理伤口(如果存在伤口还没完全愈合的情况的话),然后尽快就近前往正规接种点看医生,在医生的诊断和指导下进行相应的一系列必要的妥善处理和救治措施后接种疫苗。所有医生认为有必要的处理过程都必不可少而且都一定要尽早!只有这样才能在最大程度上保证在病毒致病之前能及时地使人体得到保护并清除体内可能存在的病毒从而最终防止狂犬病的发生!最后接种疫苗后要想确认是否有效,可在疫苗全程接种后半个月左右检查血清狂犬病抗体水平(但一般不建议或不鼓励恐友们在接种后都去检测抗体水平,详情可见本词条中的“狂犬疫苗”下的“接种疫苗后抗体水平的检测”一节),如为阴性,应加强免疫。有少数人疫苗全程注射后,抗体始终不阳转或滴度达不到抗感染的标准,最主要的可能原因是机体本身体液免疫反应能力弱或存在缺陷。这时最好测定细胞免疫指标,细胞免疫反应强也可抵抗病毒攻击。一般而言,接种后抗体阳转,以及全程接种了合格的狂犬病疫苗,尤其是合并使用狂犬病免疫球蛋白或抗狂犬病血清后半个月仍未发生狂犬病,则狂犬病疫苗免疫失败的几率较小,一般不会再发生狂犬病。另外,如果伤人的动物在伤人后十日或之后仍表现健康(没有发生狂犬病也即不是“疯动物”),则一般认为被伤者不会被感染狂犬病病毒,也即一般不会有发病的危险,这就是世界卫生组织提出的“十日观察法”。当然,一旦被任何健康状况不明的动物所伤,即要立即开始一系列暴露后处理流程!而不能有任何侥幸心理!

  总之,被伤后,经所有上述的这一系列的妥当处理之后,在最后接种完全程疫苗后半个月左右还没有发病的,则一般不会再发病了。而且对恐狂者们来说,这时能做的都已经做了,所以是到了应将恐狂情结放下的时候了,日后也应尽量远离一切健康状况不明的野生动物同时也应尽量避免与任何健康状况不明的猫狗等宠物亲密接触。另外,生命在狂犬病这一概念上是没有极限的,即使被真正的带毒疯动物咬伤后,在不注射任何免疫球蛋白或抗血清或接种疫苗的自然情况下,也只有平均30%到70%的人发病,其中很重要的可能原因之一就是:对相当一部份人而言,其自身机体的各种生理或免疫机制有效地抵抗住了病毒的攻击并最终有效地清除了被感染的病毒。再比如自然界就有多种蝙蝠和一种野生土狼在被感染狂犬病病毒后,它们的机体在自然情况下即能有效地产生各种免疫机制抵抗住了病毒的攻击从而不会发病。

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    2016-04-24 忠诚向上

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    2016-04-24 忠诚向上

    继续努力

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=82289, encodeId=659582289e9, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=137, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82284, encodeId=3aa9822849f, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82285, encodeId=693b8228594, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82286, encodeId=f11882286b2, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82287, encodeId=4bbf8228ef5, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82288, encodeId=beea82288c5, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82291, encodeId=e1fb8229194, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=171, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82293, encodeId=a87382293eb, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82292, encodeId=3f9f8229226, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82283, encodeId=9f1d8228368, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=)]
    2016-04-24 忠诚向上

    继续努力

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=82289, encodeId=659582289e9, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=137, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82284, encodeId=3aa9822849f, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82285, encodeId=693b8228594, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82286, encodeId=f11882286b2, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82287, encodeId=4bbf8228ef5, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82288, encodeId=beea82288c5, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82291, encodeId=e1fb8229194, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=171, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82293, encodeId=a87382293eb, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82292, encodeId=3f9f8229226, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82283, encodeId=9f1d8228368, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=)]
    2016-04-24 忠诚向上

    继续努力

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=82289, encodeId=659582289e9, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=137, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82284, encodeId=3aa9822849f, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82285, encodeId=693b8228594, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82286, encodeId=f11882286b2, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82287, encodeId=4bbf8228ef5, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82288, encodeId=beea82288c5, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82291, encodeId=e1fb8229194, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=171, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82293, encodeId=a87382293eb, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82292, encodeId=3f9f8229226, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82283, encodeId=9f1d8228368, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=)]
    2016-04-24 忠诚向上

    继续努力

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=82289, encodeId=659582289e9, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=137, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82284, encodeId=3aa9822849f, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82285, encodeId=693b8228594, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82286, encodeId=f11882286b2, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82287, encodeId=4bbf8228ef5, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82288, encodeId=beea82288c5, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82291, encodeId=e1fb8229194, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=171, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82293, encodeId=a87382293eb, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82292, encodeId=3f9f8229226, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82283, encodeId=9f1d8228368, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=)]
    2016-04-24 忠诚向上

    继续努力

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=82289, encodeId=659582289e9, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=137, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82284, encodeId=3aa9822849f, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82285, encodeId=693b8228594, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82286, encodeId=f11882286b2, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82287, encodeId=4bbf8228ef5, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82288, encodeId=beea82288c5, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82291, encodeId=e1fb8229194, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=171, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82293, encodeId=a87382293eb, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82292, encodeId=3f9f8229226, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82283, encodeId=9f1d8228368, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=)]
    2016-04-24 忠诚向上

    继续努力

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=82289, encodeId=659582289e9, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=137, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82284, encodeId=3aa9822849f, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82285, encodeId=693b8228594, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82286, encodeId=f11882286b2, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82287, encodeId=4bbf8228ef5, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82288, encodeId=beea82288c5, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82291, encodeId=e1fb8229194, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=171, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82293, encodeId=a87382293eb, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82292, encodeId=3f9f8229226, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82283, encodeId=9f1d8228368, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=)]
    2016-04-24 忠诚向上

    继续努力

    0

  10. [GetPortalCommentsPageByObjectIdResponse(id=82289, encodeId=659582289e9, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=137, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82284, encodeId=3aa9822849f, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82285, encodeId=693b8228594, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82286, encodeId=f11882286b2, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82287, encodeId=4bbf8228ef5, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82288, encodeId=beea82288c5, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82291, encodeId=e1fb8229194, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=171, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82293, encodeId=a87382293eb, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82292, encodeId=3f9f8229226, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82283, encodeId=9f1d8228368, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 08:00:00 CST 2016, time=2016-04-24, status=1, ipAttribution=)]
    2016-04-24 忠诚向上

    继续努力

    0

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